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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

Technological advances in gene sequencing and computing have led to an explosion in the availability of bioinformatic data and processing power, respectively, creating a ripe nexus for artificial intelligence (AI) to design strategies for controlling cell behavior.

4 Mar 2024

Can the modulation of the gut microbiome using a prebiotic improve muscle function and cognition?

Researchers examined the efficacy of a prebiotic in improving muscular and cognitive performance vs. a placebo among elderly individuals.

4 Mar 2024

Researchers discover how "leaky" mitochondria can drive harmful inflammation

Researchers have discovered how "leaky" mitochondria – the powerhouses of our cells – can drive harmful inflammation responsible for diseases such as lupus and rheumatoid arthritis.

4 Mar 2024

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

Scientists have developed a new screening tool to uncover how genetic changes affect gene activity and can lead to diseases such as cancer, autoimmunity, neurodegeneration and cardiovascular disease. This new tool enables the investigation of thousands of DNA mutations identified by genetic studies in one experiment, guiding the development of advanced diagnostics and treatments.

4 Mar 2024

New ISS investigation expands genes in space toolkit for student spaceflight experiments

For nearly a decade, Genes in Space™ has challenged students to develop spaceflight experiments that use biotechnology to address spaceflight challenges.

4 Mar 2024

PharmaKure partners with Sheffield Hallam University to develop epigenetic markers for Alzheimer’s disease prediction

PharmaKure, a clinical stage pharmaceutical company developing precision medicines for Alzheimer’s Disease (AD) and other neurodegenerative diseases, today announces a new epigenetics collaboration with Sheffield Hallam University.

4 Mar 2024

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium in the human gut, Bacteroides fragilis, protect itself from tetracycline, a widely used antibiotic.

1 Mar 2024

Exploring the epigenetic impact of smoking across racial and ethnic groups

Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses.

1 Mar 2024

Educational attainment linked to slower aging and increased longevity

Participants in the Framingham Heart Study who achieved higher levels of education tended to age more slowly and went on to live longer lives as compared to those who did not achieve upward educational mobility, according to a new study at Columbia University Mailman School of Public Health and The Robert N. Butler Columbia Aging Center.

1 Mar 2024

Penn engineers develop targeted lung delivery system using lipid nanoparticles

Penn Engineers have developed a new means of targeting the lungs with lipid nanoparticles (LNPs), the miniscule capsules used by the Moderna and Pfizer-BioNTech COVID-19 vaccines to deliver mRNA, opening the door to novel treatments for pulmonary diseases like cystic fibrosis.

1 Mar 2024

Scientists discover a key mechanism used by human herpesvirus 8 to induce cancer

Cleveland Clinic researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer.

1 Mar 2024

The association between diet and colorectal cancer risk

The genetic variants that modify the association between diet and colorectal cancer (CRC) risk.

1 Mar 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

Breakthrough CRISPR technique unlocks insights about cancer immunology

Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer.

29 Feb 2024

PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

New collaboration will enhance ability to identify those more at risk of developing brain diseases to enable earlier interventions.

From PharmaKure 29 Feb 2024

UCLA researchers uncover dual role of GAN gene in neurological disorder, head and neck cancer

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center show for the first time that a gene usually linked to giant axonal neuropathy, a rare and severe neurological condition, also plays a role in inhibiting aggressive tumor cell growth in head and neck cancers.

29 Feb 2024

Consistent Evidence Links Ultra-Processed Food To Over 30 Damaging Health Outcomes

Consistent evidence shows that higher exposure to ultra-processed foods is associated with an increased risk of 32 damaging health outcomes including cancer, major heart and lung conditions, mental health disorders, and early death.

29 Feb 2024

New tool unravels the mystery of DNA-RNA interactions in single cells

Cancers begin with abnormal changes in individual cells, and the ability to track the accumulation of mutations at the single-cell level can shed new light on the early stages of the disease. Such knowledge could enable more effective early detection and treatment options for patients as well as more accurate predictions of disease progression.

29 Feb 2024

GTF2I gene's role in Williams syndrome and autism unraveled

Individuals with the neurodevelopmental disorder Williams syndrome have a gregarious "cocktail party" personality, while those with the opposite genetic alteration, in contrast, tend to have autistic traits and are prone to struggle socially.

28 Feb 2024

Study reveals high prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from the Salento peninsula

A new research paper was published in Oncotarget's Volume 15 on February 22, 2024, entitled, "Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health."

28 Feb 2024

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DNA News and Research

Further Reading

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

Can the modulation of the gut microbiome using a prebiotic improve muscle function and cognition?

Researchers discover how "leaky" mitochondria can drive harmful inflammation

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

New ISS investigation expands genes in space toolkit for student spaceflight experiments

PharmaKure partners with Sheffield Hallam University to develop epigenetic markers for Alzheimer’s disease prediction

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Exploring the epigenetic impact of smoking across racial and ethnic groups

Educational attainment linked to slower aging and increased longevity

Penn engineers develop targeted lung delivery system using lipid nanoparticles

Scientists discover a key mechanism used by human herpesvirus 8 to induce cancer

The association between diet and colorectal cancer risk

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Breakthrough CRISPR technique unlocks insights about cancer immunology

PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

UCLA researchers uncover dual role of GAN gene in neurological disorder, head and neck cancer

Consistent Evidence Links Ultra-Processed Food To Over 30 Damaging Health Outcomes

New tool unravels the mystery of DNA-RNA interactions in single cells

GTF2I gene's role in Williams syndrome and autism unraveled

Study reveals high prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from the Salento peninsula

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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