Dopaminergic News and Research

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Differential gene expression linked to alcohol use disorder, offering new treatment possibilities

Researchers identified key gene expression differences in addiction-relevant brain regions that provide new insights into alcohol use disorder and potential therapeutic targets.

14 Oct 2024

New magnetogenetics technology holds promise as a powerful tool for studying the brain

A new technology enables the control of specific brain circuits non-invasively with magnetic fields, according to a preclinical study from researchers at Weill Cornell Medicine, The Rockefeller University and the Icahn School of Medicine at Mount Sinai.

10 Oct 2024

Replicating Lewy body formation in living neurons to understand Parkinson's disease

Lewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.

8 Oct 2024

New study challenges dopamine's role in placebo effects and pain relief

New findings argue against a direct causal role for dopamine during the experience of a treatment effect in the establishment of positive treatment expectations and placebo analgesia in healthy volunteers, according to a study published September 24th in the open-access journal PLOS Biology by Ulrike Bingel from University Hospital Essen, Germany, and colleagues.

24 Sep 2024

Wearable sensors developed to detect brain disorders through eye movement

A University of Houston engineering team has developed wearable sensors to examine eye movement to assess brain disorders or damage to the brain.

16 Sep 2024

New microscopy technique detects early Parkinson's disease indicators

Researchers at Tel Aviv University cooperated with three major Israeli medical centers to develop a new method for detecting protein aggregation in cells – a hallmark of Parkinson's disease.

16 Sep 2024

High-dose amphetamine use linked to increased risk of psychosis or mania

Prescribing rates for stimulants that treat attention-deficit/hyperactivity disorder (ADHD) have increased significantly over the past decade, with some of the largest increases reported during the COVID-19 pandemic.

12 Sep 2024

Study shows delayed feedback enhances learning in traumatic brain injury

Kessler Foundation researchers have published a novel study exploring the effects of delayed feedback on learning in individuals with moderate-to-severe traumatic brain injury (TBI).

11 Sep 2024

How diet shapes gut microbiota and affects brain function

Researchers discuss the diet-microbiota-gut-brain axis, which describes the role of both diet and gut microbiota composition on cognitive and emotional health.

26 Aug 2024

AI-driven adaptive deep brain stimulation improves Parkinson’s symptoms

Researchers compare the safety and feasibility of an adaptive deep brain stimulation (aDBS) system to a conventional DBS system for Parkinson's disease.

22 Aug 2024

Study uncovers rare genetic variants associated with Parkinson's disease

Scientists at deCODE genetics, a subsidiary of AMGEN, have discovered rare sequence variants, predicted to cause a loss of function of ITSN1, that are associated with a high risk of Parkinson's Disease.

16 Aug 2024

Dopaminergic drug levodopa linked to better sleep in Parkinson’s patients

A study involving 22 Parkinson's disease (PD) patients has shown that use of the dopaminergic drug levodopa improves sleep quality.

13 Aug 2024

New insights into lipid-induced senescence in dopaminergic neurons

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, "Lipid accumulation drives cellular senescence in dopaminergic neurons."

13 Aug 2024

Seaweed extract shows promise in protecting neurons in Parkinson’s disease

Ecklonia cava polyphenols (ECPs) show promise in reducing neuronal damage caused by rotenone in Parkinson’s disease (PD) by activating the Nrf2-ARE pathway, highlighting their potential as a neuroprotective treatment.

7 Aug 2024

Seaweed antioxidants show promise in preventing Parkinson's disease

Parkinson's disease is a neurodegenerative disease caused by the loss of neurons that produce dopamine, a neurotransmitter involved in motor control and cognitive function.

5 Aug 2024

Weight loss reduces risky decisions and boosts mood in highly obese individuals, study finds

Researchers examine how significant weight loss in highly obese individuals influences their metabolism, psychological state, and decision-making processes.

21 Jul 2024

Psilocybin reconfigures brain networks, showing potential for lasting therapeutic effects

Researchers found that high-dose psilocybin significantly disrupts brain functional connectivity, particularly in the default mode network, with lasting effects linked to therapeutic benefits.

18 Jul 2024

Novel insights into how exercise functions as an antidepressant

Researchers from University College London propose a novel framework linking reduced inflammation and boosted dopamine transmission through exercise to alleviate depressive symptoms.

18 Jul 2024

Single-cell profiling of lateral septum neurons reveals LSEsr1's role in METH addiction

Recently, a research team led by Dr. ZHU Yingjie from the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences has published a study in Neuron, the study presents a comprehensive transcriptional profile of the lateral septum (LS) at the single-cell level, elucidating the spatial distribution of its major neuronal types.

3 Jul 2024