Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Integrated approach addresses some of the biggest challenges in natural products drug discovery

Integrated approach addresses some of the biggest challenges in natural products drug discovery

New, nanotech-based strategy could enable safe, long-term treatment for autoimmune diseases

New, nanotech-based strategy could enable safe, long-term treatment for autoimmune diseases

Phase 2 clinical trial of DS-1211 begins for individuals with Pseudoxanthoma Elasticum

Phase 2 clinical trial of DS-1211 begins for individuals with Pseudoxanthoma Elasticum

Metrion Biosciences invests in new High Throughput Screening capability and expanded facilities

Metrion Biosciences invests in new High Throughput Screening capability and expanded facilities

Fingerprint-embedding framework can help find novel drug candidates

Fingerprint-embedding framework can help find novel drug candidates

Cannabidiol and the shifting perspective of epilepsy drug discovery

Cannabidiol and the shifting perspective of epilepsy drug discovery

New computer-based platform could make drug discovery process more efficient and less expensive

New computer-based platform could make drug discovery process more efficient and less expensive

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

Optibrium appoints Ian Smith as Chief Technology Officer

Optibrium appoints Ian Smith as Chief Technology Officer

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

NIAID awards more than $12 million for the development of antiviral therapies

NIAID awards more than $12 million for the development of antiviral therapies

Scientists identify a class of drugs that may prevent alcohol use disorder in people with PTSD

Scientists identify a class of drugs that may prevent alcohol use disorder in people with PTSD

Researchers to develop brain imaging radiotracers for better understanding of Alzheimer's, autism

Researchers to develop brain imaging radiotracers for better understanding of Alzheimer's, autism

Molecular motion of many 'undruggable' proteins reveals previously unseen binding sites

Molecular motion of many 'undruggable' proteins reveals previously unseen binding sites

New Community of Experts launched to harness social media data for patient-centric drug development

New Community of Experts launched to harness social media data for patient-centric drug development

Augmented drug preferentially eliminates cancer cells but does not harm healthy cells

Augmented drug preferentially eliminates cancer cells but does not harm healthy cells

Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2

Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2

Sanford Burnham Prebys researchers receive ACS grants to advance work on difficult-to-treat cancers

Sanford Burnham Prebys researchers receive ACS grants to advance work on difficult-to-treat cancers