Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Breakthrough in mirror molecule synthesis opens doors for drug discovery

Breakthrough in mirror molecule synthesis opens doors for drug discovery

Skin pigmentation may affect drug efficacy and safety

Skin pigmentation may affect drug efficacy and safety

Novel compounds show promise in fighting COVID-19

Novel compounds show promise in fighting COVID-19

Clonal competition assays reveal tumor cell resistance mechanisms

Clonal competition assays reveal tumor cell resistance mechanisms

Replicating Lewy body formation in living neurons to understand Parkinson's disease

Replicating Lewy body formation in living neurons to understand Parkinson's disease

Revolutionizing drug discovery with SmartCADD

Revolutionizing drug discovery with SmartCADD

Mosaic Therapeutics appoints Dr Barry Davies as CSO

Mosaic Therapeutics appoints Dr Barry Davies as CSO

New deep-learning framework identifies non-addictive pain relief options

New deep-learning framework identifies non-addictive pain relief options

KiNet web portal enhances study of kinase functions in cellular signaling pathways

KiNet web portal enhances study of kinase functions in cellular signaling pathways

Novel semi-synthetic compound shows promise against drug-resistant tuberculosis

Novel semi-synthetic compound shows promise against drug-resistant tuberculosis

Researchers make breakthrough in Alzheimer's disease drug development

Researchers make breakthrough in Alzheimer's disease drug development

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Study reveals rising pharmaceutical industry sponsored clinical trials in the U.S.

Study reveals rising pharmaceutical industry sponsored clinical trials in the U.S.

Global leaders unite to tackle drug-resistant bacteria

Global leaders unite to tackle drug-resistant bacteria

FUJIFILM Irvine Scientific adds key products to its Life Sciences portfolio from FUJIFILM Wako Chemicals U.S.A.

FUJIFILM Irvine Scientific adds key products to its Life Sciences portfolio from FUJIFILM Wako Chemicals U.S.A.

TxGNN improves drug repurposing by predicting treatments for rare diseases with no approved therapies

TxGNN improves drug repurposing by predicting treatments for rare diseases with no approved therapies

Study links semaglutide to reduced opioid overdose risk in patients with OUD and diabetes

Study links semaglutide to reduced opioid overdose risk in patients with OUD and diabetes

New AI tool revolutionizes drug discovery for rare diseases

New AI tool revolutionizes drug discovery for rare diseases

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

ACBI3 molecule offers new hope for targeting KRAS mutations in cancer

ACBI3 molecule offers new hope for targeting KRAS mutations in cancer

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