Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Nemours Children’s Health scientists receive two NIH grants to advance pediatric cancer research

Nemours Children’s Health scientists receive two NIH grants to advance pediatric cancer research

Venomtech announces new drug development collaboration with Charles River

Venomtech announces new drug development collaboration with Charles River

Nanocell COVID-19 vaccine elicits potent neutralizing response

Nanocell COVID-19 vaccine elicits potent neutralizing response

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

High-throughput screening assay could identify new prostate cancer drugs

High-throughput screening assay could identify new prostate cancer drugs

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

Arrayjet introduces Mercury range of next-generation microarray printers

Arrayjet introduces Mercury range of next-generation microarray printers

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Clinical health outcomes of omicron ‘less severe’ than delta for pediatric patients

Clinical health outcomes of omicron ‘less severe’ than delta for pediatric patients

Drawing on experience to achieve IVDR certification

Drawing on experience to achieve IVDR certification

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

New tissue-clearing method could speed the study of many disease-related biological processes

New tissue-clearing method could speed the study of many disease-related biological processes

Utilizing AI to Accelerate the Field of High Content Analysis

Utilizing AI to Accelerate the Field of High Content Analysis

CDK6: a potential drug target for severe COVID-19

CDK6: a potential drug target for severe COVID-19

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Powerful tool to monitor membrane proteins trafficking for drug discovery

Powerful tool to monitor membrane proteins trafficking for drug discovery

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern