Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Moffitt researchers develop novel reagent for efficient synthesis of sulfur-containing drug candidates

Moffitt researchers develop novel reagent for efficient synthesis of sulfur-containing drug candidates

WFIRM leads $40M regenerative medicine initiative for the wounded and beyond

WFIRM leads $40M regenerative medicine initiative for the wounded and beyond

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

AI scores breakthrough in anemia treatment with novel PHD inhibitor

AI scores breakthrough in anemia treatment with novel PHD inhibitor

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

Conscience's open science competition yields hits for new Parkinson's drugs

Conscience's open science competition yields hits for new Parkinson's drugs

Pioneering Genomic Progress: An Interview with Rami Mehio, Illumina's Software and Informatics Expert

Pioneering Genomic Progress: An Interview with Rami Mehio, Illumina's Software and Informatics Expert

New analysis of cancer cells identifies 370 targets for smarter, personalized treatments

New analysis of cancer cells identifies 370 targets for smarter, personalized treatments

3D nanomatrix vascular sheet model for high-throughput atherosclerosis drug testing

3D nanomatrix vascular sheet model for high-throughput atherosclerosis drug testing

When mass spectrometry redefines the pharma industry

When mass spectrometry redefines the pharma industry

New molecule targets key protein in autoimmune diseases

New molecule targets key protein in autoimmune diseases

New developments at Evosep to make clinical proteomics 100x more robust and 10x faster

New developments at Evosep to make clinical proteomics 100x more robust and 10x faster

SickKids scientists untangle cellular waste buildup in Zellweger Spectrum Disorder

SickKids scientists untangle cellular waste buildup in Zellweger Spectrum Disorder

Scripps scientists debunk long-held theory about alcohol and the brain

Scripps scientists debunk long-held theory about alcohol and the brain

New test detects Parkinson's disease before symptoms appear

New test detects Parkinson's disease before symptoms appear

Scripps Research commemorates 100 years of innovation in science and medicine

Scripps Research commemorates 100 years of innovation in science and medicine

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'