Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Drug discovery pipeline to exploit transcription factors for cancer therapy

Drug discovery pipeline to exploit transcription factors for cancer therapy

Researchers receive $1.3 million grant to develop better treatments for Alzheimer's disease

Researchers receive $1.3 million grant to develop better treatments for Alzheimer's disease

Researchers identify underlying mechanism for metabolic memory and diabetic complications

Researchers identify underlying mechanism for metabolic memory and diabetic complications

Scientists discover promising drug target for dry age-related macular degeneration

Scientists discover promising drug target for dry age-related macular degeneration

American beautyberry leaf extract boosts antibiotic's activity against 'superbug'

American beautyberry leaf extract boosts antibiotic's activity against 'superbug'

Dopamine therapy improves cognitive function in patients with mild-to-moderate Alzheimer's

Dopamine therapy improves cognitive function in patients with mild-to-moderate Alzheimer's

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

NanoSurface Biomedical is now Curi Bio

NanoSurface Biomedical is now Curi Bio

Mobility and flexibility in SARS-CoV-2 proteins

Mobility and flexibility in SARS-CoV-2 proteins

Deep Longevity and Human Longevity announce collaboration to deploy AI-powered aging clocks

Deep Longevity and Human Longevity announce collaboration to deploy AI-powered aging clocks

Novel drug could enable the immune system to attack ovarian cancer

Novel drug could enable the immune system to attack ovarian cancer

High-resolution TB-PET/CT scanner reveals complete picture of systemic inflammatory arthritis

High-resolution TB-PET/CT scanner reveals complete picture of systemic inflammatory arthritis

Newly discovered chemical compound shows potential to become treatment for brain disorders

Newly discovered chemical compound shows potential to become treatment for brain disorders

Novel testicular luminal protein is vital for male fertility

Novel testicular luminal protein is vital for male fertility

Insilico Medicine, Arctoris announce technology partnership to discover new COVID-19 drugs

Insilico Medicine, Arctoris announce technology partnership to discover new COVID-19 drugs

X-ray scattering technique reveals mechanisms of protein folding

X-ray scattering technique reveals mechanisms of protein folding

Structure of the SARS-CoV-2 spike protein provides clues to its evolution

Structure of the SARS-CoV-2 spike protein provides clues to its evolution

Optibrium and NCSSM celebrate 5 years of education support collaboration

Optibrium and NCSSM celebrate 5 years of education support collaboration

PRMT5 inhibitors can help treat advanced melanoma

PRMT5 inhibitors can help treat advanced melanoma

Horizon Discovery introduces Cas9 and dCas9-VPR stable cell lines to simplify and accelerate CRISPR gene editing workflows

Horizon Discovery introduces Cas9 and dCas9-VPR stable cell lines to simplify and accelerate CRISPR gene editing workflows