Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
The obstacles to developing high-throughput 3D wound healing models

The obstacles to developing high-throughput 3D wound healing models

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

Study unveils several natural marine products as potential agents against SARS-CoV-2

Study unveils several natural marine products as potential agents against SARS-CoV-2

Optical coherence tomography reveals the beating and development of human heart organoids

Optical coherence tomography reveals the beating and development of human heart organoids

Acacetin shows potency against SARS-CoV-2 spike protein

Acacetin shows potency against SARS-CoV-2 spike protein

Mason scientists receive DOD funding for breast cancer prevention and treatment research

Mason scientists receive DOD funding for breast cancer prevention and treatment research

New smartphone app can calculate users’ genetic risk for coronary artery disease

New smartphone app can calculate users’ genetic risk for coronary artery disease

Canadian scientist discusses about how society could better prepare for future pandemics

Canadian scientist discusses about how society could better prepare for future pandemics

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

COVID-19 and the life sciences; what have we learned and where are we going?

COVID-19 and the life sciences; what have we learned and where are we going?

Novel drug candidate protects lab mice against cognitive decline by reducing brain inflammation

Novel drug candidate protects lab mice against cognitive decline by reducing brain inflammation

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Optibrium Adds Augmented Intelligence for Compound Design to its StarDrop Small Molecule Drug Discovery Software

Optibrium Adds Augmented Intelligence for Compound Design to its StarDrop Small Molecule Drug Discovery Software

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Semarion raises £2.14 million GBP ($2.89 million USD) seed funding

Semarion raises £2.14 million GBP ($2.89 million USD) seed funding

Cell stress-related biochemical events may be partly driving Parkinson's disease

Cell stress-related biochemical events may be partly driving Parkinson's disease

Automata raises US $50 million in series B financing to accelerate automation in life science

Automata raises US $50 million in series B financing to accelerate automation in life science

Certain flavonoids inhibit an enzyme involved in the formation of key hormone in yellow fever mosquito

Certain flavonoids inhibit an enzyme involved in the formation of key hormone in yellow fever mosquito

Ensitrelvir, a novel SARS-CoV-2 antiviral

Ensitrelvir, a novel SARS-CoV-2 antiviral

Researchers overcome key challenge in creating sulfur-based medicines

Researchers overcome key challenge in creating sulfur-based medicines