Estradiol News and Research

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Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

Study may explain why hormone therapy slows progression of heart disease

As one of the most common treatments for effectively managing menopause symptoms, hormone therapy (HT) is also known to provide multiple health benefits, including slowing the progression of atherosclerosis.

28 Sep 2020

NAMS publishes the 2020 Genitourinary Syndrome Of Menopause Position Statement

The North American Menopause Society announces publication of its 2020 Genitourinary Syndrome of Menopause Position Statement.

1 Sep 2020

Study suggests role for estrogen replacement to protect women against Alzheimer's

Biological sex influences the effect of amyloid beta on alterations to tau protein characteristic to Alzheimer's disease, suggesting a role for estradiol in preventing the disease in women, report scientists in the Journal of Alzheimer's Disease

1 Sep 2020

Estradiol appears to help in female SARS-CoV-2 infection

A new study published on the preprint server medRxiv in August 2020 shows that the risk of infection is high for pre-menopausal women but the risk of death is much higher for men in the same age group and throws light on the protective nature of estradiol therapy in post-menopausal women.

26 Aug 2020

A wearable sensor printed on natural polymer for monitoring body fluids present in sweat

A wearable sensor printed on microbial nanocellulose, a natural polymer, has been created in Brazil by researchers at the University of São Paulo in São Carlos in collaboration with colleagues at São Paulo State University in Araraquara, the University of Araraquara, the University of Campinas, and the Brazilian National Nanotechnology Laboratory.

17 Aug 2020

TGen review: Postmenopausal women at higher risk for developing NALFD

A review article authored by a researcher at the Translational Genomics Research Institute, an affiliate of City of Hope, suggests that following menopause, women are at higher risk for developing nonalcoholic fatty liver disease, a chronic condition caused by the build-up of excess fat in the liver not caused by alcohol.

14 Aug 2020

$New studies identify contributors to higher risk of stress fractures in female runners$

New studies identify contributors to higher risk of stress fractures in female runners

Running is one of the most popular forms of exercise, enjoyed by a broad range of age groups and skill levels. More women are running recreationally compared to men; specifically 54% of runners are female as indicated by a 2018 National Runner Survey.

11 Aug 2020

Estrogen modestly protective against COVID-19?

Almost from the beginning, scientists have been struck by the disproportionately higher numbers of men and older adults who have developed severe COVID-19 disease compared to younger individuals and women. Prior research has shown that in 37 of the 38 countries from which sex-stratified data was available, males were at a higher risk of death. Also, post-menopausal women are at increased risk of severe COVID-19. However, the biological underpinnings of this have been less visible.

4 Aug 2020

War of sugars - estrogen provides protection in COVID-19

Now a new study published on the preprint server bioRxiv in July 2020 reports that sex hormones could affect the function of the fusion protein that is dependent upon the human ACE2 receptor, thus preventing the entry of the virus into the host cell.

31 Jul 2020

Sex lives of leeches can shed light on endocrine disrupting chemicals

Today, we pull the veil back on the secret sex lives of leeches and how researchers at McMaster University and Fisheries and Oceans Canada are using that information to learn about endocrine disrupting chemicals.

21 Jul 2020

Small molecule drugs binding Mac1 domain of SARS-CoV-2

Now, an intriguing new study out of the University of Wisconsin-Milwaukee reveals that numerous small molecule drugs like the proton pump inhibitors omeprazole and rabeprazole bind the important Mac1 domain on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus.

8 Jul 2020

Age-related structural brain changes are linked to hormone-level changes

Sex hormones influence the structure and function of the brain, but little is known about the effect of hormone therapies (HT) on changes in the brain during menopause.

10 Jun 2020

Study: Genes may play a far more complex role in oocyte maturation than previously assumed

Over the last six years a group of Estonian geneticists led by Associate Professor Agne Velthut-Meikas and a PhD student Ilmatar Rooda from TalTech Department of Chemistry and Biotechnology have studied genes previously associated primarily with female hormone synthesis and ovarian follicle development.

7 May 2020

Study provides new insight into neurofibromin-deficient ER+ breast cancer

An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene.

5 Mar 2020

Menopause age not associated with heart disease finds study

There has been conflicting evidence regarding early menopause and an increased risk for heart disease among women. This connection has been attributed to the lowering of female hormone estrogen levels in the blood.

26 Feb 2020

Living in greener neighborhoods may delay onset of menopause

Living near green spaces is associated with a wide variety of benefits, including a lower risk of obesity, improved attention capacity in children and slower physical decline in old age.

13 Feb 2020

Nutrition researcher shows how foods affect our hormones and health

Nutrition researcher and New York Times bestselling author Neal Barnard, MD, demonstrates how foods affect our hormones--and our health--in his new book, Your Body in Balance.

13 Feb 2020

Scientists develop computationally inspired method for preclinical study of anxiety

Nearly 40 million people in the U.S. have an anxiety disorder. While treatment options exist, treatment success varies, and many people do not respond to treatment until weeks or months after they begin anti-depressants

18 Dec 2019

Lower levels of 'free' testosterone found in women with asthma

Women with asthma appear more likely to have lower levels of "free" (not attached to proteins) testosterone than women who do not have asthma, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

30 Sep 2019

Higher dosage of statins can increase risk of osteoporosis, shows study

At low doses, statins could protect against bone resorption. But the higher the dosage of cholesterol-lowering drugs, the greater the probability of osteoporosis, an analysis of millions of patient data by the Complexity Science Hub Vienna shows.