Estradiol News and Research

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Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

Estrogen modestly protective against COVID-19?

Almost from the beginning, scientists have been struck by the disproportionately higher numbers of men and older adults who have developed severe COVID-19 disease compared to younger individuals and women. Prior research has shown that in 37 of the 38 countries from which sex-stratified data was available, males were at a higher risk of death. Also, post-menopausal women are at increased risk of severe COVID-19. However, the biological underpinnings of this have been less visible.

4 Aug 2020

War of sugars - estrogen provides protection in COVID-19

Now a new study published on the preprint server bioRxiv in July 2020 reports that sex hormones could affect the function of the fusion protein that is dependent upon the human ACE2 receptor, thus preventing the entry of the virus into the host cell.

31 Jul 2020

Sex lives of leeches can shed light on endocrine disrupting chemicals

Today, we pull the veil back on the secret sex lives of leeches and how researchers at McMaster University and Fisheries and Oceans Canada are using that information to learn about endocrine disrupting chemicals.

21 Jul 2020

Small molecule drugs binding Mac1 domain of SARS-CoV-2

Now, an intriguing new study out of the University of Wisconsin-Milwaukee reveals that numerous small molecule drugs like the proton pump inhibitors omeprazole and rabeprazole bind the important Mac1 domain on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus.

8 Jul 2020

Age-related structural brain changes are linked to hormone-level changes

Sex hormones influence the structure and function of the brain, but little is known about the effect of hormone therapies (HT) on changes in the brain during menopause.

10 Jun 2020

Study: Genes may play a far more complex role in oocyte maturation than previously assumed

Over the last six years a group of Estonian geneticists led by Associate Professor Agne Velthut-Meikas and a PhD student Ilmatar Rooda from TalTech Department of Chemistry and Biotechnology have studied genes previously associated primarily with female hormone synthesis and ovarian follicle development.

7 May 2020

Study provides new insight into neurofibromin-deficient ER+ breast cancer

An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene.

5 Mar 2020

Menopause age not associated with heart disease finds study

There has been conflicting evidence regarding early menopause and an increased risk for heart disease among women. This connection has been attributed to the lowering of female hormone estrogen levels in the blood.

26 Feb 2020

Living in greener neighborhoods may delay onset of menopause

Living near green spaces is associated with a wide variety of benefits, including a lower risk of obesity, improved attention capacity in children and slower physical decline in old age.

13 Feb 2020

Nutrition researcher shows how foods affect our hormones and health

Nutrition researcher and New York Times bestselling author Neal Barnard, MD, demonstrates how foods affect our hormones--and our health--in his new book, Your Body in Balance.

13 Feb 2020

Scientists develop computationally inspired method for preclinical study of anxiety

Nearly 40 million people in the U.S. have an anxiety disorder. While treatment options exist, treatment success varies, and many people do not respond to treatment until weeks or months after they begin anti-depressants

18 Dec 2019

Lower levels of 'free' testosterone found in women with asthma

Women with asthma appear more likely to have lower levels of "free" (not attached to proteins) testosterone than women who do not have asthma, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

30 Sep 2019

Higher dosage of statins can increase risk of osteoporosis, shows study

At low doses, statins could protect against bone resorption. But the higher the dosage of cholesterol-lowering drugs, the greater the probability of osteoporosis, an analysis of millions of patient data by the Complexity Science Hub Vienna shows.

30 Sep 2019

Study identifies determinants of estradiol levels among women using hormone therapy

The benefits of hormone therapy on atherosclerosis relates to achieved estradiol levels among those women who initiate HT early in postmenopause. Despite the use of hormones, however, women's estradiol levels are often inconsistent.

24 Sep 2019

Most breast cancer cases could be prevented by simple lifestyle modifications

Expert reports estimate that one in three breast cancer cases could be prevented by lifestyle modifications. Those modifications include such basics as weight management, physical activity, nutrition, and alcohol consumption, among others.

24 Sep 2019

Researchers seek to identify biomarkers that may predict suicide risk among women

A four-year, $3.1 million grant from the National Institute of Mental Health will help researchers determine how the stabilization of ovarian hormones estradiol and progesterone may help lower symptoms associated with suicidality among females with longstanding thoughts of suicide.

5 Aug 2019

Estrogen exposure during fetal life increases autism risk

In a new study, scientists confirmed that babies who are exposed to higher levels of estrogen while they are in the womb are more likely to be autistic. The study titled, 'Foetal oestrogens and autism', is published in the journal, Molecular Psychiatry.

30 Jul 2019

New book explains about the molecular mechanisms implicated in skeletal muscle aging

Sarcopenia, the progressive loss of muscle mass and associated muscle weakness during aging, affects the functional capacity and general health in adult people radically and renders frail elders susceptible to serious injury from sudden falls and fractures.

21 Jul 2019

Women's greater immune response to flu vaccine declines with age

Women tend to have a greater immune response to a flu vaccination compared to men, but their advantage largely disappears as they age and their estrogen levels decline, suggests a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

17 Jul 2019

Study uncovers potential new way to prevent common pregnancy-related complications

About 1 in 10 pregnant women experience placenta abnormalities that lead to life-threatening preeclampsia (hypertension), preterm labor and fetal growth problems, but finding effective treatments to effectively prevent or reverse these conditions has so far been elusive.

19 Jun 2019