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Scientists identify new susceptibility genes in genome-wide association study of nasopharyngeal carcinoma

Scientists from Singapore, China and USA have identified three new susceptibility genes in a genome-wide association study of nasopharyngeal carcinoma (NPC). The study, led by the Genome Institute of Singapore (GIS), a biomedical research institute of the Agency for Science, Technology and Research (A*STAR), and the Sun Yat-Sen University Cancer Centre, identified genetic risk factors of NPC that advance the understanding of the important role played by host genetic variation in influencing the susceptibility to this cancer.

31 May 2010

BioSpace launches 2010 BioCapital Hotbed Campaign

The leading career Web site for the life sciences launched the 2010 BioCapital™ Hotbed Campaign this morning, marking the campaign's 10th edition and highlighting multiple companies within Washington D.C., Delaware, Maryland and Virginia. Each company participant's brand is added to an electronic and printed campaign map that is promoted online as well as at industry events and career fairs.

29 May 2010

Various aspects of consumer genetics to be discussed at 2nd Annual Consumer Genetics Conference

At the 2nd Annual Consumer Genetics Conference taking place in Boston from June 2-4 at the Hynes Convention Center, these issues will be addressed and preeminent leaders from varying areas of expertise will provide perspectives on these crucial topics that are shaping the way we approach clinical medicine and helping to improve patient outcomes.

29 May 2010

Hitachi Software, OriGene announce co-marketing agreement

Hitachi Software Engineering America, Ltd. and OriGene Technologies, Inc. today announced a co-marketing agreement to jointly promote OriGene's multiplex assays built on Luminex xMAP/Bio-Plex technology and Hitachi Software's MasterPlex software suite for analysis and reporting of multiplex assay data.

29 May 2010

Roche launches GS Junior System benchtop DNA sequencing platform for life science research

Roche, announced today the global launch of the GS Junior System, the company's new benchtop next-generation DNA sequencing platform for life science research. The GS Junior System, developed by 454 Life Sciences, a Roche company, provides an integrated sequencing and bioinformatics solution, all in a size that is no bigger than a typical desktop laser printer.

From Roche Sequencing and Life Science 28 May 2010

UT Southwestern researchers create 35 new rat "lines" with mutations in specific genes

For two decades, the laboratory mouse has been the workhorse of biomedical studies and the only mammal whose genes scientists could effectively and reliably manipulate to study human diseases and conditions.

28 May 2010

Bone marrow transplant cures excessive pathological grooming behavior in mice

Scientists earlier found that mice missing one of a group of core developmental genes known as the Hox genes developed an odd and rather unexpected pathology: the mutant animals groomed themselves compulsively to the point that they were removing their own hair and leaving self-inflicted open sores on their skin. Now, they've found a surprising connection between the Hoxb8 gene and the behavior that looks an awful lot like that of people with an obsessive compulsive spectrum disorder (OCD).

28 May 2010

Genentech uses Complete Genomics' sequencing service to compare primary lung tumor, adjacent normal tissue

Complete Genomics Inc., a third-generation human genome sequencing company, today announced that Genentech Inc., a wholly owned member of the Roche Group, used the company's sequencing, bioinformatics and analytics services to sequence and compare a patient's primary lung tumor and adjacent normal tissue.

27 May 2010

Mount Sinai School of Medicine deploys Isilon scale-out NAS for DNA sequencing and analysis workflow

Isilon® Systems today announced that Mount Sinai School of Medicine's Genomics Institute and Department of Genetics and Genomic Sciences has deployed Isilon scale-out NAS as the primary repository for its next-generation DNA sequencing and analysis workflow.

27 May 2010

Bacteria may play wider role in people predisposed to obesity: Researchers

Bacteria may play more of a role in people predisposed to obesity than previously thought, according to studies presented today by University of Maryland School of Medicine researchers at the 110th general meeting of the American Society for Microbiology in San Diego.

27 May 2010

Researchers report key cellular pathway in deadly brain cancer malignant glioma

Researchers at the University of Massachusetts Medical School report in the journal Nature Medicine on a cellular pathway in the deadly brain cancer malignant glioma, a pathway essential to the cancer's ability to grow - and a potential target for therapy that would stop the cancer's ability to thrive.

26 May 2010

Researchers use zebrafish as model to analyze function of every known mutation in BBS

A research team led by scientists from the Duke University Medical Center has developed a way to simultaneously look at the effects of 125 mutations occurring on 14 different genes. They used zebrafish as a model to analyze the function of every known mutation in an inherited syndrome called BBS, Bardet-Biedl Syndrome.

25 May 2010

New research finding may change direction of vaccine research for M. tuberculosis

Scientists at NYU Langone Medical Center have discovered that the strategy of "immune evasion" common to many viruses, bacteria and parasites, is uncommon to M. tuberculosis where the antigens remain strikingly unchanged and homogenous. The study published in Nature Genetics on May 23, 2010, suggests that M. tuberculosis antigens do not mutate because they hope to be recognized by the body's immune system- perhaps because the host immune mechanism that leads to the typical lung destruction and cough can contribute to the spread of the disease.

25 May 2010

Researchers identify mechanisms involved in gene mutation

Genetic variation due to DNA mutation is a driving force of adaptation and evolution, as well as a contributing factor to disease. However, the mechanisms governing DNA mutation rate are not well understood.

25 May 2010

A unique multi-modal atlas of human brain

The Allen Institute for Brain Science announced today that it has launched the Allen Human Brain Atlas, a publicly available online atlas charting genes at work throughout the human brain.

25 May 2010

FDA clears Simplexa Influenza A H1N1 (2009) test

The U.S. Food and Drug Administration today announced it has cleared the Simplexa Influenza A H1N1 (2009), a test for the 2009 H1N1 Influenza Virus in patients with signs and symptoms of respiratory infection.

24 May 2010

Expression Analysis agrees to purchase PacBio RS DNA sequencing system from Pacific Biosciences

Expression Analysis, a leading provider of genomic services for clinical trials and research, announced today that it has agreed to purchase a PacBio RS DNA sequencing system from northern-California based Pacific Biosciences, whose third-generation DNA sequencing technology is expected to revolutionize the field of genetic analysis through the use of single molecule real time detection of biological events.

24 May 2010

Sangamo's ZFP Therapeutics technology highlighted at ASGCT Annual Meeting

Sangamo BioSciences, Inc. announced today that data from research and preclinical programs focused on the development of zinc finger DNA-binding protein Therapeutics were described in fifteen presentations given by Sangamo scientists and collaborators at the 13th Annual Meeting of the American Society of Gene and Cell Therapy.

24 May 2010

Scientists identify new gene candidates that regulate aggregate formations in Huntington's disease

They might not be known for their big brains, but fruit flies are helping to make scientists and doctors smarter about what causes Huntington's disease and how to treat it. New research, published in the journal GENETICS (http://www.genetics.org) describes a laboratory test that allows scientists to evaluate large numbers of fruit fly genes for a possible role in the formation of plaque-like protein aggregates within cells.

24 May 2010

European researchers define research priorities in biogerontology

The quality of the medical care for geriatric patients is a major investment for society and must imperatively be a research priority in Europe. This is why 50 European researchers, met on May 17 - 19 in Brussels, to define the research priorities in the field of biogerontology for the next 10 to 15 years.

21 May 2010

Genome News and Research

Scientists identify new susceptibility genes in genome-wide association study of nasopharyngeal carcinoma

BioSpace launches 2010 BioCapital Hotbed Campaign

Various aspects of consumer genetics to be discussed at 2nd Annual Consumer Genetics Conference

Hitachi Software, OriGene announce co-marketing agreement

Roche launches GS Junior System benchtop DNA sequencing platform for life science research

UT Southwestern researchers create 35 new rat "lines" with mutations in specific genes

Bone marrow transplant cures excessive pathological grooming behavior in mice

Genentech uses Complete Genomics' sequencing service to compare primary lung tumor, adjacent normal tissue

Mount Sinai School of Medicine deploys Isilon scale-out NAS for DNA sequencing and analysis workflow

Bacteria may play wider role in people predisposed to obesity: Researchers

Researchers report key cellular pathway in deadly brain cancer malignant glioma

Researchers use zebrafish as model to analyze function of every known mutation in BBS

New research finding may change direction of vaccine research for M. tuberculosis

Researchers identify mechanisms involved in gene mutation

A unique multi-modal atlas of human brain

FDA clears Simplexa Influenza A H1N1 (2009) test

Expression Analysis agrees to purchase PacBio RS DNA sequencing system from Pacific Biosciences

Sangamo's ZFP Therapeutics technology highlighted at ASGCT Annual Meeting

Scientists identify new gene candidates that regulate aggregate formations in Huntington's disease

European researchers define research priorities in biogerontology

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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