Hemolytic Uremic Syndrome News and Research

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Acute renal failure in young children is most commonly linked to hemolytic uremic syndrome (HUS). In this situation, it often comes as a shock, occurring as it does in a child who was previously healthy but is now in mortal danger. This illness is caused by the toxin produced by certain bacterial strains, most commonly found in beef.

Genetic analysis reveals hidden causes of chronic kidney disease in adults

Chronic kidney disease (CKD) is extremely prevalent among adults, affecting over 800 million individuals worldwide.

3 Apr 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs -; with the addition of an also already FDA-approved complement inhibitor -; are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Meridian Bioscience announces FDA clearance for innovative Curian® Shiga Toxin Assay

Meridian Bioscience, Inc., a leading global provider of diagnostic testing solutions and life science raw materials.

From Meridian Bioscience, Inc. 18 Sep 2023

Stalled progress: Enteric infection reduction efforts slowed in 2022 despite pandemic easing

The research paper focuses on the lack of progress in reducing enteric infection incidence in 2022 despite the subsiding influence of the COVID-19 pandemic. It emphasizes the need for collaborative efforts among food stakeholders and regulators to mitigate pathogen contamination during poultry slaughter and prevent contamination of leafy greens.

3 Jul 2023

Scientists develop a model human gut microbiome

A team of US-based scientists has developed a novel bacterial community comprising 119 microbial species naturally found in the human body. The study is published in the journal Cell.

7 Sep 2022

CDC provides latest updates on the number of individuals infected with E. coli O157 outbreak strain

A CDC investigation notice update regarding a multistate outbreak of E. coli O157 infections is now live: https://www.cdc.gov/ecoli/2022/o157h7-08-22/index.html

2 Sep 2022

New update on CDC's investigation of multistate outbreak of E. coli O157 infection

A CDC investigation notice update regarding a multistate outbreak of E. coli O157 infections is now live: https://www.cdc.gov/ecoli/2022/o157h7-08-22/index.html

26 Aug 2022

Researchers identify a promising method to stop COVID-19 infection

While the world waits eagerly for a safe and effective vaccine to prevent infections from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus behind the COVID-19 pandemic, researchers also are focusing on better understanding how SARS-CoV-2 attacks the body in the search for other means of stopping its devastating impact.

8 Oct 2020

Genomic analysis of specific E. coli strain can help develop potential vaccines

Foodborne pathogens are very common and usually benign, but certain virulent strains of pathogens can result in severe disease and even death.

3 Sep 2020

Study: E. coli Nissle may also protect human cells against other pathogenic strains

Typically, there aren't a lot of positive thoughts when E. coli, generally found in animal and human intestines, is mentioned. It's been blamed for closing beaches and swimming pools and shuttering restaurants because of contamination in salad bars, meats or other food items.

8 Jul 2020

E.coli infections linked to chopped salad kits, CDC warns

You might want to ditch your salad this holiday season, as the Centers for Disease Control and Prevention (CDC) and the U.S. Food and Drug Administration (FDA) warn against an outbreak of Escherichia coli (E.coli) linked to chopped salad kits.

18 Dec 2019

Bacteriophages could treat E. coli without damaging the gut, new study says

Researchers in the US have developed a new therapy that uses a unique bacteriophage to treat E. coli infections.

13 Nov 2019

New technique to detect common cause for diseases related to thrombotic microangiopathies

There is a group of diseases whose symptoms have a common origin: a lesion in the endothelial tissue that covers the inside of the blood vessels.

8 Nov 2019

Researchers find synergistic connection between two deadly blood-clotting diseases

Two rare but potentially deadly blood-clotting diseases, namely thrombotic thrombocytopenic purpura, or TTP, and hemolytic uremic syndrome, or HUS, show similar pathologies -- a multitude of painful blockages in small blood vessels that cause varying degrees of organ injury throughout the body. However, the two disorders have distinct biological mechanisms.

8 Sep 2019

FDA approves first drug for treatment of neuromyelitis optica spectrum disorder

The U.S. Food and Drug Administration today approved Soliris (eculizumab) injection for intravenous use for the treatment of neuromyelitis optica spectrum disorder in adult patients who are anti-aquaporin-4 antibody positive.

27 Jun 2019

Multistate E. coli outbreak says CDC

The Centers for Disease Control and Prevention (CDC) is looking at a Shiga toxin-producing Escherichia coli outbreak that has spilled across state borders to affect people living in at least five states.

7 Apr 2019

Human microbiome metabolites enhance colon injury by enterohemorrhagic E. coli, study shows

It remains mysterious why humans get infected by some bacterial or viral pathogens relatively easily while animals that have very similar tissues and immune functions do not.

20 Mar 2019

Viral replication not necessary to cause lethal disease by food-borne pathogen

The replication of a bacterial virus is not necessary to cause lethal disease in a mouse model of a food-borne pathogen called Enterohemorrhagic Escherichia coli, according to a study published January 10 in the open-access journal PLOS Pathogens by Sowmya Balasubramanian, John Leong and Marcia Osburne of Tufts University School of Medicine, and colleagues.

10 Jan 2019

University of Cincinnati professor awarded $1.6 million NIAID grant to study Hamburger E. coli

Alison Weiss, PhD, professor in the Department of Molecular Genetics, Biochemistry and Microbiology in UC College of Medicine, has been awarded a four-year grant of $1.6 million from the National Institute of Allergy and Infectious Diseases to study Shiga toxin producing Escherichia coli 0157:H7, also sometimes referred to as Hamburger E. coli.

9 Jan 2019

Researchers shed new light on how to combat Shiga and ricin toxins

Min Dong, PhD, and his lab are world experts in toxins and how to combat them. They've figured out how Clostridium difficile's most potent toxin gets into cells and zeroed in on the first new botulinum toxin identified since 1969.

11 Dec 2018