Huntington's Disease News and Research

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Huntington's disease (HD) results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance. HD is a familial disease, passed from parent to child through a mutation in the normal gene. Each child of an HD parent has a 50-50 chance of inheriting the HD gene. If a child does not inherit the HD gene, he or she will not develop the disease and cannot pass it to subsequent generations. A person who inherits the HD gene will sooner or later develop the disease. Whether one child inherits the gene has no bearing on whether others will or will not inherit the gene. Some early symptoms of HD are mood swings, depression, irritability or trouble driving, learning new things, remembering a fact, or making a decision. As the disease progresses, concentration on intellectual tasks becomes increasingly difficult and the patient may have difficulty feeding himself or herself and swallowing. The rate of disease progression and the age of onset vary from person to person. A genetic test, coupled with a complete medical history and neurological and laboratory tests, helps physicians diagnose HD. Presymptomic testing is available for individuals who are at risk for carrying the HD gene. In 1 to 3 percent of individuals with HD, no family history of HD can be found.
Family experience guides Alzheimer’s research

Family experience guides Alzheimer’s research

Autophagy may even provide a clue to the mythical fountain of youth

Autophagy may even provide a clue to the mythical fountain of youth

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Robotic microscope shows how mutant Huntington's disease protein affects neurons

Robotic microscope shows how mutant Huntington's disease protein affects neurons

Pregnant women are at higher risk for restless legs syndrome

Pregnant women are at higher risk for restless legs syndrome

Study on RNAi technology targeting neurodegenerative diseases

Study on RNAi technology targeting neurodegenerative diseases

Effects of Huntington's disease mutation more complex than originally thought

Effects of Huntington's disease mutation more complex than originally thought

Researchers shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease

Researchers shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease

£18m to upgrade genetic laboratories in England

£18m to upgrade genetic laboratories in England

Gene therapy may provide a treatment for a group of incurable, progressive neurological diseases called polyglutamine-repeat diseases

Gene therapy may provide a treatment for a group of incurable, progressive neurological diseases called polyglutamine-repeat diseases

New insights into a mysterious type of amnesia

New insights into a mysterious type of amnesia

Cellular garbage plays a key role in the process of cytokinesis, or cell division

Cellular garbage plays a key role in the process of cytokinesis, or cell division

Specialists work to overcome Huntington's disease

Specialists work to overcome Huntington's disease

Cell research to eventually develop new treatments for cancer and disorders such as Parkinson’s and Huntington’s disease

Cell research to eventually develop new treatments for cancer and disorders such as Parkinson’s and Huntington’s disease

A common antibiotic used to treat arthritis and acne shows promise for limiting the severity of spinal cord and brain injuries

A common antibiotic used to treat arthritis and acne shows promise for limiting the severity of spinal cord and brain injuries