Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Engineered proteins track gene expression in living primate brains

Gene therapy has been successfully used to treat a number of diseases, including immune deficiencies, hereditary blindness, hemophilia and, recently, Huntington's disease, a fatal neurological disorder.

27 Feb 2026

Study elucidates key steps in the ubiquitin tagging of mutated huntingtin protein

Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future therapies.

5 Feb 2026

Unfolding the role of Hsp70 chaperones in neurodegeneration

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom management.

22 Jan 2026

Using AI to understand the age of disease onset in Huntington's patients

A team from the Faculty of Medicine and Health Sciences and the Institute of Neurosciences at the University of Barcelona (UBneuro) has applied advanced artificial intelligence techniques to better understand why Huntington's disease can begin at very different ages in patients.

20 Jan 2026

Axol Bioscience raises $2.8 M to advance US expansion and product development

Axol Bioscience Ltd. (Axol), a leading provider of induced pluripotent stem cell (iPSC) technologies for drug discovery and disease research, today announced that it has secured $2.8 million (£2.1 million) in funding.

13 Jan 2026

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Scientists at Johns Hopkins Medicine say results of a new National Institutes of Health-funded study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

30 Dec 2025

UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington's disease

Leslie M. Thompson, Donald Bren Professor of psychiatry and human behavior as well as neurobiology and behavior at the University of California, Irvine, has received an $11,999,933 grant from the California Institute for Regenerative Medicine for an unprecedented clinical trial of a novel neural stem cell therapy for Huntington's disease.

12 Dec 2025

Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease

Synaptic plasticity — the brain's ability to modify the connections between neurons to support learning — is one of the neural functions profoundly altered in Huntington's disease, with a direct impact on brain function.

10 Dec 2025

Subtle changes in the composition of short tandem repeats may shape disease risk

Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that could help explain why people experience disease differently, and why some treatments work better for certain populations.

14 Nov 2025

Novel vitamin K analogs show promise for reversing neurodegenerative diseases

Neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's disease are characterized by the progressive loss of neurons.

13 Sep 2025

AI breakthrough designs peptide drugs to target previously untreatable proteins

A study published in Nature Biotechnology reveals a powerful new use for artificial intelligence: designing small, drug-like molecules that can stick to and break down harmful proteins in the body - even when scientists don't know what those proteins look like.

13 Aug 2025

Johns Hopkins uncovers protein's unexpected role in brain signaling

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with genetically engineered mice.

4 Aug 2025

Healthy glial cell transplants slow Huntington’s disease progression

Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not only slowed motor and cognitive decline but also extended lifespan.

17 Jun 2025

Smartphone tests could enhance the detection of Huntington's disease progression

A series of digital tests, carried out via a smartphone app, could enhance the detection of disease progression in Huntington's disease and improve the efficiency of clinical trials, finds research led by scientists at University College London (UCL) and Roche.

9 Jun 2025

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy.

21 May 2025

New cases of dementia decline while prevalence continues to increase due to population aging

New cases of dementia in the United States declined from 2015 to 2021, but the number of people living with the condition continued to rise due to population aging, with nearly 2.9 million traditional Medicare beneficiaries (around 12%) living with a dementia diagnosis in 2021, finds a study published by The BMJ today.

21 May 2025

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

12 May 2025

Study reveals opposing roles of two proteins in Huntington's disease

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease?

5 May 2025

Researchers uncover genetic link between autism spectrum disorder and myotonic dystrophy type 1

Scientists from The Hospital for Sick Children (SickKids) and University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition called myotonic dystrophy type 1 (DM1).

21 Apr 2025

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Experimental drug NU-9 - a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) - improves neuron health in animal models of Alzheimer's disease, according to a new Northwestern University study.

8 Apr 2025

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Engineered proteins track gene expression in living primate brains

Study elucidates key steps in the ubiquitin tagging of mutated huntingtin protein

Unfolding the role of Hsp70 chaperones in neurodegeneration

Using AI to understand the age of disease onset in Huntington's patients

Axol Bioscience raises $2.8 M to advance US expansion and product development

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington's disease

Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease

Subtle changes in the composition of short tandem repeats may shape disease risk

Novel vitamin K analogs show promise for reversing neurodegenerative diseases

AI breakthrough designs peptide drugs to target previously untreatable proteins

Johns Hopkins uncovers protein's unexpected role in brain signaling

Healthy glial cell transplants slow Huntington’s disease progression

Smartphone tests could enhance the detection of Huntington's disease progression

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

New cases of dementia decline while prevalence continues to increase due to population aging

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Study reveals opposing roles of two proteins in Huntington's disease

Researchers uncover genetic link between autism spectrum disorder and myotonic dystrophy type 1

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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