Huntington's Disease News and Research

Latest Huntington's Disease News and Research

New cases of dementia decline while prevalence continues to increase due to population aging

New cases of dementia in the United States declined from 2015 to 2021, but the number of people living with the condition continued to rise due to population aging, with nearly 2.9 million traditional Medicare beneficiaries (around 12%) living with a dementia diagnosis in 2021, finds a study published by The BMJ today.

21 May 2025

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

12 May 2025

Study reveals opposing roles of two proteins in Huntington's disease

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease?

5 May 2025

Researchers uncover genetic link between autism spectrum disorder and myotonic dystrophy type 1

Scientists from The Hospital for Sick Children (SickKids) and University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition called myotonic dystrophy type 1 (DM1).

21 Apr 2025

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Experimental drug NU-9 - a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) - improves neuron health in animal models of Alzheimer's disease, according to a new Northwestern University study.

8 Apr 2025

Human dental stem cells can be transformed into excitable neuronal cells, study shows

The cells with electrophysiological activity obtained at the University of the Basque Country (UPV/EHU) are opening up new avenues for the study of neurodegenerative diseases and the development of future autologous transplants.

7 Apr 2025

New neurons rebuild damaged circuits in Huntington’s disease

New research shows that the adult brain can generate new neurons that integrate into key motor circuits. The findings demonstrate that stimulating natural brain processes may help repair damaged neural networks in Huntington's and other diseases.

7 Apr 2025

Advanced imaging technique reveals how nuclear pores regulate molecular movement

Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into and out of the nucleus.

22 Mar 2025

Exploring the role of subventricular zone in neural regeneration, neurodegenerative diseases

This recently published exploration into the subventricular zone (SVZ) highlights its critical role in neural regeneration, neurodegenerative diseases, and glioblastoma multiforme (GBM).

5 Mar 2025

UCLA study reveals key role of mismatch repair genes in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

11 Feb 2025

Neurostimulation improves movement in adults with spinal muscle atrophy

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease.

5 Feb 2025

Decades of DNA expansion linked to Huntington’s disease neurodegeneration

Researchers uncover how slow CAG repeat expansions in neurons drive Huntington’s disease over decades.

24 Jan 2025

APOBEC proteins linked to DNA repeat expansion in Huntington's disease

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time.

22 Jan 2025

Early brain changes in Huntington’s disease detected two decades before symptoms

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease, finds a new study led by UCL researchers.

17 Jan 2025

Scientists discover new mechanism behind Huntington’s disease brain cell death

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

16 Jan 2025

Could autophagy enhancement slow aging and combat Alzheimer's?

How cellular cleanup systems could hold the key to slowing aging and halting neurodegeneration.

9 Jan 2025

Researchers uncover molecular mechanisms driving RNA processing defects in Huntington's disease

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as amyotrophic lateral sclerosis, frontotemporal lobar dementia and Alzheimer's disease.

8 Jan 2025

SPLICER shows promise in Alzheimer's and other diseases

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

23 Dec 2024

Heart medication may slow the progression of Huntington's disease

Research indicates β-blockers may reduce the risk of motor diagnosis and slow symptom progression in Huntington's disease, suggesting new management approaches.

4 Dec 2024

Beta-blocker drugs may slow Huntington's disease progression

A common heart drug may slow the progression of Huntington's disease (HD), according to a new study by University of Iowa Health Care researchers.

2 Dec 2024

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

New cases of dementia decline while prevalence continues to increase due to population aging

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Study reveals opposing roles of two proteins in Huntington's disease

Researchers uncover genetic link between autism spectrum disorder and myotonic dystrophy type 1

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Human dental stem cells can be transformed into excitable neuronal cells, study shows

New neurons rebuild damaged circuits in Huntington’s disease

Advanced imaging technique reveals how nuclear pores regulate molecular movement

Exploring the role of subventricular zone in neural regeneration, neurodegenerative diseases

UCLA study reveals key role of mismatch repair genes in Huntington’s disease

Neurostimulation improves movement in adults with spinal muscle atrophy

Decades of DNA expansion linked to Huntington’s disease neurodegeneration

APOBEC proteins linked to DNA repeat expansion in Huntington's disease

Early brain changes in Huntington’s disease detected two decades before symptoms

Scientists discover new mechanism behind Huntington’s disease brain cell death

Could autophagy enhancement slow aging and combat Alzheimer's?

Researchers uncover molecular mechanisms driving RNA processing defects in Huntington's disease

SPLICER shows promise in Alzheimer's and other diseases

Heart medication may slow the progression of Huntington's disease

Beta-blocker drugs may slow Huntington's disease progression

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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