Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models.

2 Feb 2022

Gene therapy can provide long-lasting therapeutic benefit in Huntington's disease

Gene therapy targeting the messenger RNA (mRNA) of the mutated huntingtin gene (HTT) can provide long-lasting therapeutic benefit in Huntington's disease after a single administration.

25 Jan 2022

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Protein misfolding is a likely culprit in many degenerative disorders. Cystic fibrosis, for instance, is caused by mutations in the CFTR gene that prevent the eponymous protein from assuming its proper configuration.

24 Jan 2022

JPND announces call for multinational research on understanding the mechanisms of non-pharmacological interventions

The EU Joint Programme - Neurodegenerative Disease Research (JPND) initiative has announced a joint transnational call for multinational research on understanding the mechanisms of non-pharmacological interventions.

10 Jan 2022

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Advanced technique reveals the ultrastructure of huntingtin inclusion bodies

Huntington's disease is a progressively debilitating brain disease that causes uncontrolled movements, psychological problems, and loss of cognition.

12 Nov 2021

New technology shows great promise for early diagnosis of Alzheimer’s disease

A technology developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) shows great promise for diagnosing Alzheimer's disease before symptoms arise, potentially changing the course of research and treatment for this condition, which affects millions of people worldwide and is estimated to be the sixth leading cause of death in the United States.

7 Oct 2021

Toxic fatty acids trigger cell death in damaged neurons

Cells that normally nourish healthy brain cells called neurons release toxic fatty acids after neurons are damaged, a new study in rodents shows.

6 Oct 2021

Buck Institute receives $14 million NIH grant to focus on one of the major drivers of aging

Buck Institute professors Judith Campisi, PhD and Lisa Ellerby PhD, have been awarded a $14.3 million grant from the NIH's National Institute of Aging to study cellular senescence, one of the major hallmarks of aging, as a driver of Alzheimer's disease and other age-related dementias.

29 Sep 2021

Study focuses on psychiatric, cognitive symptoms emerging at early stages of Huntington's disease

Psychiatric and cognitive symptoms emerge at an early stage in Huntington's disease. However, research so far has mainly focused on movement impairment, a symptom associated with the more advanced stages of the disease.

7 Sep 2021

Breakthrough study could lead to much needed therapies for Huntington's disease

A new mechanism that stops the progression of Huntington's disease in cells has been identified by scientists at UCL and the University of Cambridge, as part of their research groups at the UK Dementia Research Institute.

31 Aug 2021

Review highlights similarities between long COVID and chronic fatigue syndrome

A team of researchers, including two from Johns Hopkins Medicine, have published a review article highlighting similarities between certain lingering symptoms following COVID-19 illness — a condition called "long COVID" — and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating, complex disorder previously known as chronic fatigue syndrome.

26 Aug 2021

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Key protein linked to both physical fitness in youth and diseases of old age

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

4 Aug 2021

Novel microfluidic device used to manipulate major whey protein

After gaining world attention by 'unboiling' egg protein, Flinders University scientists have now used an Australian-made novel thin film microfluidic device to manipulate Beta-lactoglobulin (β-lactoglobulin), the major whey protein in cow's, sheep's and other mammals.

26 Jul 2021

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

Huntington's Disease (HD) is a progressive neurodegenerative condition characterized by motor, cognitive, and psychiatric symptoms, and motor symptoms are often preceded by cognitive changes.

15 Jul 2021

Dying patients with rare diseases struggle to get experimental therapies

At 15, Autumn Fuernisen is dying. She was diagnosed at age 11 with a rare degenerative brain disorder that has no known cure or way to slow it down: juvenile-onset Huntington's disease.

14 Jul 2021

Mass spectrometry: An important tool to unravel mechanisms underlying Huntington's disease

Mass spectrometry has emerged as an important analytical tool for gaining a better understanding of mechanisms underlying Huntington's disease (HD), alongside the increased availability of cell and animal models of the disease.

14 Jul 2021

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington's disease, a neurodegenerative disorder that attacks brain cells.

7 Jul 2021

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Researchers create a comprehensive atlas of cerebrovascular cell types

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Gene therapy can provide long-lasting therapeutic benefit in Huntington's disease

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

JPND announces call for multinational research on understanding the mechanisms of non-pharmacological interventions

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Advanced technique reveals the ultrastructure of huntingtin inclusion bodies

New technology shows great promise for early diagnosis of Alzheimer’s disease

Toxic fatty acids trigger cell death in damaged neurons

Buck Institute receives $14 million NIH grant to focus on one of the major drivers of aging

Study focuses on psychiatric, cognitive symptoms emerging at early stages of Huntington's disease

Breakthrough study could lead to much needed therapies for Huntington's disease

Review highlights similarities between long COVID and chronic fatigue syndrome

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Key protein linked to both physical fitness in youth and diseases of old age

Novel microfluidic device used to manipulate major whey protein

Autophagy disruption may be at the root of early cognitive changes in Huntington’s disease

Dying patients with rare diseases struggle to get experimental therapies

Mass spectrometry: An important tool to unravel mechanisms underlying Huntington's disease

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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