Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Study finds 50% increase in hospitalizations for alcoholic hepatitis in early months of the pandemic

In new research published in Liver International, researchers at Henry Ford Health System have found that people hospitalized for alcoholic hepatitis – a life threatening liver disease fueled by alcohol use – increased a staggering 50 percent in the early months of the COVID-19 pandemic.

9 Feb 2022

Maternal metabolic syndrome can switch on imprinted gene associated with NAFLD in offspring

New research from North Carolina State University has found that an imprinted gene associated with development of non-alcoholic fatty liver disease (NAFLD) is switched on in mice who nurse from mothers with metabolic syndrome, even when those mice are not biologically related.

7 Feb 2022

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

Researchers from the University of California, Irvine have discovered that the absence of Adiponectin receptor 1 protein (AdipoR1), one of the principal enzymes regulating ceramide homeostasis in the retina, leads to an accumulation of ceramides in the retina, resulting in progressive photoreceptor cell death and ultimately vision loss.

28 Jan 2022

UofL professor wins $6.7 million grant to investigate how metals cause lung cancer

For nearly three decades, John Pierce Wise Sr. has investigated the connection between exposure to metals and cancer, working both in the lab and in the field, reporting significant discoveries about the effects of metals on chromosomes in lung cancer and how those effects differ in humans and in whales.

27 Jan 2022

Study highlights the risk of kidney disease and obesity in people with type 1 diabetes

People with type 1 diabetes should be screened regularly for obesity and chronic kidney disease, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

27 Jan 2022

Study finds poorer outcomes after ICU discharge in patients with alcohol-associated cirrhosis

Patients with alcohol-associated cirrhosis have poorer outcomes after ICU discharge, compared to patients with cirrhosis linked to other causes, according to new Mayo Clinic research.

25 Jan 2022

Eligible adults urged to take part in world-first COVID-19 study of antivirals

Adults over the age of 50 or with an underlying health condition who test positive for COVID-19 are being urged to sign up for a world-first COVID-19 study which is providing life-saving antivirals to thousands of people.

24 Jan 2022

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

A commercial-stage company focused on generating data-driven insights to diagnose, understand and treat rare diseases, and Insilico Medicine, an end-to-end Artificial Intelligence (AI) - driven drug discovery company, today announced a research and development collaboration to accelerate the discovery of novel therapeutic targets for Niemann-Pick disease type C

21 Jan 2022

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, according to a new study in mice from Washington University School of Medicine in St. Louis.

19 Jan 2022

Scientific review highlights the impact of coffee on digestive organs

A new scientific review, published in Nutrients, highlights coffee's effects on digestion and the gut, and its impact on organs involved in digestion.

19 Jan 2022

Study explores COVID-19 diagnosis and outcomes in HIV patients

In a new study, researchers determined the effect of the human immunodeficiency virus (HIV) on coronavirus disease 2019 (COVID-19) diagnosis and disease outcomes and compared to those without HIV.

19 Jan 2022

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

Researchers investigate the efficacy of hydroxychloroquine and chloroquine in the treatment of patients hospitalized with COVID-19.

17 Jan 2022

ASTRO provides new guidance on the use of external beam radiation therapy for primary liver cancers

A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides guidance on the use of radiation therapy to treat adult patients with primary liver cancers using external beam radiation therapy (EBRT).

12 Jan 2022

Association of obstructive sleep apnea with hospitalization due to COVID-19

Researchers report that OSA is an independent risk factor for severe COVID-19.

7 Jan 2022

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

An experimental immunotherapy can temporarily reprogram patients' immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2022

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

The LIVE-AIR phase 3 clinical trial is associated with early treatment of hyperinflammatory response with the humanized monoclonal antibody lenzilumab in COVID-19 patients with decreased oxygen saturation. The study results are posted to the medRxiv* preprint server.

6 Jan 2022

Both symptomatic and asymptomatic COVID-19 associated with increased risk of cardiovascular events

Researcers determine the risk of symptomatic and asymptomatic SARS-CoV-2 infection on post-acute cardiovascular events and all-cause mortality.

4 Jan 2022

New Better Health marketing campaign highlights six benefits of losing excess weight

A new Better Health marketing campaign has been launched today to help people prevent risks of developing serious illness and help reduce the risk of being hospitalised with COVID-19.

3 Jan 2022

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Drug-induced liver injury (DILI) is an adverse reaction to ingesting a drug, which can appear both in developmental stages, in their clinical use and even after being approved as a drug.

30 Dec 2021

Holiday Heart Syndrome not associated with ventricular arrhythmias, study finds

The relationship between alcohol and atrial fibrillation has long been referred to as the Holiday Heart Syndrome. An extensive study of the relationship between total alcohol consumption and cardiovascular disease determined that this phenomenon is not associated with ventricular arrhythmias (VAs).

21 Dec 2021

Liver Disease News and Research

Further Reading

Study finds 50% increase in hospitalizations for alcoholic hepatitis in early months of the pandemic

Maternal metabolic syndrome can switch on imprinted gene associated with NAFLD in offspring

Desipramine and L-cycloserine together reduce ceramide levels in the retina and enhance vision

UofL professor wins $6.7 million grant to investigate how metals cause lung cancer

Study highlights the risk of kidney disease and obesity in people with type 1 diabetes

Study finds poorer outcomes after ICU discharge in patients with alcohol-associated cirrhosis

Eligible adults urged to take part in world-first COVID-19 study of antivirals

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

Scientific review highlights the impact of coffee on digestive organs

Study explores COVID-19 diagnosis and outcomes in HIV patients

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

ASTRO provides new guidance on the use of external beam radiation therapy for primary liver cancers

Association of obstructive sleep apnea with hospitalization due to COVID-19

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

Both symptomatic and asymptomatic COVID-19 associated with increased risk of cardiovascular events

New Better Health marketing campaign highlights six benefits of losing excess weight

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Holiday Heart Syndrome not associated with ventricular arrhythmias, study finds

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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