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New machine learning approach boosts precision of cardiovascular risk assessments

Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability.

18 Sep 2024

Clinical trial finds pomalidomide effective for treating rare bleeding disorder

A clinical trial supported by the National Institutes of Health (NIH) was stopped early after researchers found sufficient evidence that a drug used to treat bone marrow cancer and Kaposi sarcoma is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that affects 1 in 5,000 people worldwide.

18 Sep 2024

Study may represent a possible surgery-free strategy for managing cataracts

Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye's lens that occurs commonly in people as they age.

18 Sep 2024

Antibiotic resistance threatens millions of lives worldwide

More than 39 million people around the world could die from antibiotic-resistant infections over the next 25 years, according to a study published in The Lancet.

18 Sep 2024

NIH-funded study compares eyelid surgeries for Trachomatous trichiasis

Trachomatous trichiasis, a potentially blinding condition where inward-turned eyelashes scratch the front of the eye, can successfully be treated by either of the two most common types of eyelid surgery, according to findings from a large comparison trial funded by the National Institutes of Health.

18 Sep 2024

New $3.26 million grant launches Undiagnosed Diseases Network site in New York

A new four-year, $3.26 million grant from the National Institute of Neurological Disorders and Stroke (NINDS), a part of the National Institutes of Health (NIH), establishes the first Undiagnosed Diseases Network (UDN) site in the New York metropolitan area.

17 Sep 2024

$4.1 million funding supports epilepsy treatment research using spider venom proteins

UQ researchers have received $4.1 million from the Medical Research Future Fund to advance their research into epilepsy treatments made from spider venom proteins.

17 Sep 2024

Postsurgical treatment with pembrolizumab doubles cancer-free time for bladder cancer patients

Results from a large clinical trial show that treatment with an immunotherapy drug may nearly double the length of time people with high-risk, muscle-invasive bladder cancer are cancer-free following surgical removal of the bladder.

17 Sep 2024

Early food insecurity linked to higher obesity risk in childhood

Children who faced food insecurity during early childhood-;or whose mothers experienced it during pregnancy-;had a higher body mass index (BMI) and more than 50% increased chance of developing obesity or severe obesity in childhood and adolescence, according to a new study funded by the NIH Environmental influences on Child Health Outcomes (ECHO) Program.

16 Sep 2024

Monoclonal antibodies could help provide an answer to antimicrobial resistance

Monoclonal antibodies – treatments developed by cloning a cell that makes an antibody – could help provide an answer to the growing problem of antimicrobial resistance, say scientists.

16 Sep 2024

Addressing anxiety in patients undergoing active surveillance for low-risk cancers

Patients with low-risk cancers undergoing active surveillance face a favorable long-term prognosis. David Haggstrom, M.D., MAS, makes the case that it's time for the medical field to help manage the anxiety caused by waiting.

16 Sep 2024

Understanding the social determinants of cardiovascular health in Asian Americans

Numerous social and structural factors, including immigration status, socioeconomic position and access to health care, contribute to differences in cardiovascular health and heart disease risk for Asian Americans, and these factors affect Asian ethnic subgroups in different ways, according to a new scientific statement published today in the American Heart Association's journal, Circulation.

16 Sep 2024

Australians with health conditions strongly advocate for ongoing COVID-19 safety measures

Study reveals that over half of Australians with underlying health conditions continue to support and follow COVID-19 mitigation measures, highlighting the ongoing public health concerns despite eased government mandates.

15 Sep 2024

NIH funds new research to combat emerging viruses

Albert Einstein College of Medicine has received a five-year, $14 million per year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to participate in a broad national effort to develop "plug-and-play" vaccines and antibody-based therapies against a wide range of emerging viruses. The grant is part of NIAID's new Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Network, which was announced earlier today.

14 Sep 2024

New research network focuses on high-priority viruses

The National Institutes of Health (NIH) has established a pandemic preparedness research network to conduct research on high-priority pathogens most likely to threaten human health with the goal of developing effective vaccines and monoclonal antibodies. Currently, many of the diseases caused by these pathogens have no available vaccines or therapeutics, and investing in this research is key to preparing for potential public health crises-;both in the United States and around the world. NIH's National Institute of Allergy and Infectious Diseases (NIAID) expects to commit approximately $100 million per year to fund the program, pending the availability of funds.

14 Sep 2024

Scientists develop selective therapy for tau tangles

Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.

14 Sep 2024

Understanding sex-specific patterns of melanoma development

Melanoma rates differ consistently between men and women in terms of the ages at which melanomas occur and the locations on the body where they occur.

13 Sep 2024

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with over 1,000,000 new cases and close to 770,000 deaths each year.

13 Sep 2024

Research highlights cardiovascular benefits of semaglutide for overweight adults with impaired kidney function

The anti-obesity medication semaglutide may help to prevent heart attacks, strokes, and other major adverse cardiovascular events (MACE) as well as death in adults with overweight or obesity who don't have diabetes, whether or not they also have impaired kidney function, according to new research to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept).

13 Sep 2024

New tool ehrapy revolutionizes health data analysis

Led by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for the analysis of complex medical health data.

12 Sep 2024

Medical Research News and Research

New machine learning approach boosts precision of cardiovascular risk assessments

Clinical trial finds pomalidomide effective for treating rare bleeding disorder

Study may represent a possible surgery-free strategy for managing cataracts

Antibiotic resistance threatens millions of lives worldwide

NIH-funded study compares eyelid surgeries for Trachomatous trichiasis

New $3.26 million grant launches Undiagnosed Diseases Network site in New York

$4.1 million funding supports epilepsy treatment research using spider venom proteins

Postsurgical treatment with pembrolizumab doubles cancer-free time for bladder cancer patients

Early food insecurity linked to higher obesity risk in childhood

Monoclonal antibodies could help provide an answer to antimicrobial resistance

Addressing anxiety in patients undergoing active surveillance for low-risk cancers

Understanding the social determinants of cardiovascular health in Asian Americans

Australians with health conditions strongly advocate for ongoing COVID-19 safety measures

NIH funds new research to combat emerging viruses

New research network focuses on high-priority viruses

Scientists develop selective therapy for tau tangles

Understanding sex-specific patterns of melanoma development

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Research highlights cardiovascular benefits of semaglutide for overweight adults with impaired kidney function

New tool ehrapy revolutionizes health data analysis

A new way of characterising biomolecules eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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