MicroRNA News and Research

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In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression.
Aggressive type of cancer provides clues to how metastases form

Aggressive type of cancer provides clues to how metastases form

Understanding the molecular mechanisms behind lung cancer relapse

Understanding the molecular mechanisms behind lung cancer relapse

Study provides a reliable early prognostic biomarker for COVID-19 severity

Study provides a reliable early prognostic biomarker for COVID-19 severity

Researchers seek to find a cure for the deadliest solid tumor in children

Researchers seek to find a cure for the deadliest solid tumor in children

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Overexpression of PGC1 in vascular smooth muscle cells ameliorates atherosclerosis

Overexpression of PGC1 in vascular smooth muscle cells ameliorates atherosclerosis

New platform can detect microRNA-205 with high sensitivity, excellent selectivity

New platform can detect microRNA-205 with high sensitivity, excellent selectivity

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Synthetic microRNA can serve as a novel therapeutic agent for treating human cancer

Synthetic microRNA can serve as a novel therapeutic agent for treating human cancer

Researchers develop proof-of-concept treatment for blood disorders

Researchers develop proof-of-concept treatment for blood disorders

Newly identified small molecule can be used to rejuvenate the brain, counteract memory loss

Newly identified small molecule can be used to rejuvenate the brain, counteract memory loss

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

New study launched to more accurately diagnose early hepatocellular carcinoma

New study launched to more accurately diagnose early hepatocellular carcinoma

Study reveals a hidden role of circulating microRNA as a driver of SARS-CoV-2 infection

Study reveals a hidden role of circulating microRNA as a driver of SARS-CoV-2 infection

New approach to scale up genome editing in tiny worms

New approach to scale up genome editing in tiny worms

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Microrna-29 molecule controls brain maturation in mammals

Microrna-29 molecule controls brain maturation in mammals

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

New biomarker of glucocorticoid action could help clinicians to tailor treatments

New biomarker of glucocorticoid action could help clinicians to tailor treatments