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Wayne State University initiates groundbreaking multiple sclerosis study

A groundbreaking study in multiple sclerosis focusing on "remyelination in the brain" has been initiated by Omar Khan, M.D., professor and chair of neurology at the Wayne State University School of Medicine.

19 Sep 2013

EpimiRNA Consortium concentrates on developing novel mRNA-based therapeutics to prevent epilepsy

Over 50 million people across the world suffer from epilepsy, making it the most common serious neurological disorder for which there is no cure. The causes for epilepsy are insufficiently understood with currently available treatments being sub-optimal and with a significant proportion of patients not responding

19 Sep 2013

Researchers identify new gene that may have ability to prevent HIV

A team of researchers led by King's College London has for the first time identified a new gene which may have the ability to prevent HIV, the virus that causes AIDS, from spreading after it enters the body.

19 Sep 2013

Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum, which is able to sense cellular stress and trigger either rescue responses or the death of the cell.

18 Sep 2013

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

A preclinical study led by researchers at Children's National Medical Center has found that a new oral drug shows early promise for the treatment of Duchenne muscular dystrophy.

18 Sep 2013

arGEN-X announces CTA filing of Phase Ib cancer study with ARGX-111

arGEN-X, a clinical stage human monoclonal antibody therapeutics company, announces today the CTA filing of a first-in-man Phase Ib cancer study with ARGX-111, its second proprietary SIMPLE Antibody product to enter the clinic this year.

17 Sep 2013

TSRI scientists find new way to boost effectiveness of anticancer drugs

Scientists at The Scripps Research Institute (TSRI) have found a way to make dramatic improvements to the cancer cell-killing power of vinblastine, one of the most successful chemotherapy drugs of the past few decades.

17 Sep 2013

Flecainide, encainide drugs increase risk of sudden cardiac death

Scientists have discovered that a drug which increases the risk of sudden cardiac death interacts with mistranslated protein-coding genes present in heart muscle.

17 Sep 2013

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

New research shows that microRNA-486 is a potent tumor-suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung-cancer cells, and the induction of programmed cell death, or apoptosis, in those cells.

17 Sep 2013

Researchers identify new link between meal times and daily changes in immune system

A new link between meal times and daily changes in the immune system has been identified by UC San Francisco researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.

17 Sep 2013

Researchers identify biomarker that can predict diabetes risk

Researchers at the Vanderbilt Heart and Vascular Institute and Massachusetts General Hospital have identified a biomarker that can predict diabetes risk up to 10 years before onset of the disease.

17 Sep 2013

Kinder chemistry promises cleaner and safer pharmaceuticals with fewer side-effects

A new and kinder chemistry promises cleaner and subsequently safer pharmaceuticals with fewer side-effects. The ground-breaking method, developed by a chemistry research group at the University of Copenhagen, is now published in the internationally renowned journal, Chemical Communications, as "Site-selective three component reaction for dual functionalization of peptides".

16 Sep 2013

Scientists develop antibiotic whose activity can be controlled using light

Scientists at the University of Groningen have developed an antibiotic whose activity can be controlled using light. It is possible to 'switch on' the substance immediately before use, after which it will slowly lose its activity.

16 Sep 2013

Researchers report first experimental evidence that supports theory of buckyball

Researchers at the Virginia Tech Carilion Research Institute have reported the first experimental evidence that supports the theory that a soccer ball-shaped nanoparticle commonly called a buckyball is the result of a breakdown of larger structures rather than being built atom-by-atom from the ground up.

16 Sep 2013

Drug used in patients for cancer treatment has beneficial effects on diabetes

A pair of studies by researchers at the Stanford University School of Medicine has identified a molecular pathway - a series of interaction among proteins - involved in the development of diabetes. Furthermore, they have found that a drug already approved for use in humans can regulate the pathway.

16 Sep 2013

Research findings bring scientists one step closer to preventing HIV infections

In a long-awaited finding, a team of Chinese and US scientists has determined the high-resolution atomic structure of a cell-surface receptor that most strains of HIV use to get into human immune cells. The researchers also showed where maraviroc, an HIV drug, attaches to cells and blocks HIV’s entry.

13 Sep 2013

Researchers develop new ways of preventing septic shock

The body's immune system is set up much like a home security system; it has sensors on the outside of cells that act like motion detectors — floodlights — that click on when there's an intruder rustling in the bushes, bacteria that seem suspect.

13 Sep 2013

New catalyst class uses halogen bridges for environmentally friendlier production

Ninety percent of all chemical products require catalysts in the course of their manufacture. They accelerate reactions and reduce the energy needed. Catalysts participate in reactions, but are not consumed. As a result one catalyst molecule can convert millions of substrate molecules, which explains the great economic value of catalysts.

13 Sep 2013

Four new pre-clinical drug development projects at NIH develop treatment for rare disease

Four new pre-clinical drug development projects at the National Institutes of Health will target a form of blindness and diseases characterized by cardiac problems. The projects were selected for their potential to treat specific rare diseases and to help scientists uncover new information that can be shared with other researchers.

13 Sep 2013

Wistar Institute receives $1.5M grant to prepare potential new prostate cancer drug for clinical use

To prepare a potential new prostate cancer drug, called Gamitrinib, for trial in humans, The Wistar Institute has received a $1.5 million grant from the US Department of Defense's Congressionally Directed Medical Research Program.

13 Sep 2013

Molecule News and Research

Wayne State University initiates groundbreaking multiple sclerosis study

EpimiRNA Consortium concentrates on developing novel mRNA-based therapeutics to prevent epilepsy

Researchers identify new gene that may have ability to prevent HIV

Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

arGEN-X announces CTA filing of Phase Ib cancer study with ARGX-111

TSRI scientists find new way to boost effectiveness of anticancer drugs

Flecainide, encainide drugs increase risk of sudden cardiac death

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

Researchers identify new link between meal times and daily changes in immune system

Researchers identify biomarker that can predict diabetes risk

Kinder chemistry promises cleaner and safer pharmaceuticals with fewer side-effects

Scientists develop antibiotic whose activity can be controlled using light

Researchers report first experimental evidence that supports theory of buckyball

Drug used in patients for cancer treatment has beneficial effects on diabetes

Research findings bring scientists one step closer to preventing HIV infections

Researchers develop new ways of preventing septic shock

New catalyst class uses halogen bridges for environmentally friendlier production

Four new pre-clinical drug development projects at NIH develop treatment for rare disease

Wistar Institute receives $1.5M grant to prepare potential new prostate cancer drug for clinical use

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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