Neuroimmunology News and Research

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Study shows intestinal involvement in the development and progression of MS

It is incompletely understood which factors in patients with multiple sclerosis (MS) act as a trigger for the immune system to attack the brain and spinal cord.

4 Dec 2019

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Scientists have determined that La Crosse virus, which can cause inflammation of the brain, or encephalitis, in children, affects brain cells differently depending on their developmental stage.

26 Nov 2019

ALS patients with commonly inherited genetic variation may experience more severe symptoms

A discovery made several years ago in a lab researching asthma at Wake Forest School of Medicine may now have implications for the treatment of amyotrophic lateral sclerosis (ALS), a disease with no known cure and only two FDA-approved drugs to treat its progression and severity.

16 Oct 2019

Multiple sclerosis genomic map implicates immune cells in disease susceptibility

The International Multiple Sclerosis Genetic Consortium reports the results of its latest study, "Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility", in the journal Science today: the highly productive collaborative group presents a new milestone in its efforts to understand the genetic basis of multiple sclerosis.

26 Sep 2019

Scientists move one step closer to discovering the causes of immune diseases

Scientists are one step closer to discovering the causes of immune diseases such as asthma, multiple sclerosis and arthritis

23 Sep 2019

Scientists discover rare autoimmune disease triggered by testicular cancer

A new autoimmune disease has been discovered that is triggered by testicular cancer. The condition is rare, but cases are growing.

8 Jul 2019

Researchers identify autoimmune disease linked with testicular cancer

Using advanced technology, scientists at Chan Zuckerberg Biohub, Mayo Clinic and University of California, San Francisco, have discovered an autoimmune disease that appears to affect men with testicular cancer.

3 Jul 2019

Novel imaging molecule reveals brain changes linked to progressive MS

Secondary progressive multiple sclerosis is a relentless disease. Over time, patients experience worsening physical, mental and mood-related symptoms.

2 Jul 2019

UAB study reveals detrimental role of neutrophils in multiple sclerosis

Multiple sclerosis is an autoimmune disease that damages the insulating sheaths of nerve cells of the central nervous system. People with the disease can lose vision, suffer weak limbs, show degenerative symptoms and exhibit impaired cognition.

26 May 2019

Drug reduces risk of relapse with neuromyelitis optica spectrum disorder, study shows

The drug eculizumab, a synthetic antibody that inhibits the inflammatory response, significantly reduced the risk of relapse with neuromyelitis optica spectrum disorder.

3 May 2019

Study of MS patients shows 18% were given wrong diagnoses

A recent study found that nearly 18 percent of patients diagnosed with multiple sclerosis before being referred to two major Los Angeles medical centers for treatment actually had been misdiagnosed with the autoimmune disease.

8 Apr 2019

Inauguration of NIDD, the Neuroimmunology Drug Development Summit

NIDD is the industry’s first meeting dedicated to targeting neuroimmunological mechanisms in order to develop clinically efficacious therapeutics.

From Neuroimmunology Drug Development 5 Apr 2019

Tactile and proprioceptive stimulation improves effects of perinatal brain injuries in mice

A research conducted by the INc-UAB shows that the same perinatal brain injury caused by hypoxia and ischemia have differentiated effects on each gender, but can be improved through tactile and proprioceptive stimuli.

5 Mar 2019

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers.

28 Feb 2019

Researchers explain why T cells lose their protective ability in inflamed tissues

Regulatory T cells make sure that immune responses are not too strong and that inflammation is inhibited. This makes them highly interesting for therapies against inflammatory autoimmune diseases such as multiple sclerosis.

20 Feb 2019

Researcher identifies putative mechanism that leads to degeneration of axons in multiple sclerosis

The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is initiated by ruptures in the cell membrane and the resulting influx of calcium ions.

25 Jan 2019

New editorial proposes changes to improve minority representation in clinical trials

In an editorial published in CNS Spectrums, Jay Avasarala, MD, PhD, takes the research community to task for its lack of minority representation in Phase III clinical trials for drugs to treat Multiple Sclerosis (MS).

2 Jan 2019

Answering the Biggest Neurological Research Questions of Today

An interview with Dr. Peggy Taylor, discussing the biggest neurological research questions of today and how BioLegend is helping to develop new biomarkers for neurological disease.

From BioLegend 14 Dec 2018

Researchers create new approach to classify patients with Alzheimer's disease

Researchers studying Alzheimer's disease have created an approach to classify patients with Alzheimer's disease, a finding that may open the door for personalized treatments.

5 Dec 2018

B cell accumulation triggers nervous system damage in MS

B cells are important in helping the immune system fight pathogens. However, in the case of the neurological autoimmune disease Multiple Sclerosis (MS) they can damage nerve tissue.

8 Nov 2018