Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

First hair-baring human skin organoid may one day help prevent hair loss

A new, hair-sprouting dollop of human skin created in the lab might one day help prevent hair loss.

3 Jun 2020

Study shows Sofosbuvir alleviates COVID-19-related neurological symptoms

A group of researchers has studied the effects of an antiviral drug Sofosbuvir on human brain organoids infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Jun 2020

ISSCR 2020 Virtual Meeting to deliver comprehensive scientific education program

The International Society for Stem Cell Research has transformed its annual scientific meeting into a virtual experience, bringing the global stem cell community together to share knowledge, collaborate, and network.

2 Jun 2020

A remote optical control for neural cells

A team led by researchers at Carnegie Mellon University has created a new technology that enhances scientists' ability to communicate with neural cells using light.

1 Jun 2020

Researchers grow lung organoids from stem cells for Sars-Cov-2 research

A Bochum-based team intends to use organoids from stem cells to study the progression of Sars-CoV-2 infection and to identify antiviral substances.

28 May 2020

Findings provide new insights into future cancer treatment

An early age of pregnancy (25 years and younger) is known to reduce the overall risk of breast cancer by over 30%. CSHL Assistant Professor Camila dos Santos spent several years teasing out the molecular details behind the protective effects of pregnancy.

27 May 2020

Researchers investigate the early development of ovarian cancer

Researchers from the group of Hans Clevers at the Hubrecht Institute have modeled the development and progression of high-grade serous ovarian cancer in mini-versions of the female reproductive organs of the mouse.

27 May 2020

Excessive blood clotting and stroke in COVID-19 patients

The coronavirus disease COVID-19 is causing excessive blood clotting and stroke in young and healthy people, a new study has found.

21 May 2020

COVID-19 may damage the central nervous system

Researchers at University Hospital Düsseldorf, Germany, have provided important insights into the potential impact that coronavirus disease 2019 (COVID-19) could have on the central nervous system.

21 May 2020

USC-Olympus partnership in multiscale bioimaging furthers precision medicine

As a global leader in endoscopy and life science solutions, Olympus has long been committed to promoting awareness of cancer screening, prevention and testing. In this spirit, the company recently forged a partnership with the Lawrence J. Ellison Institute for Transformative Medicine at the University of Southern California (USC).

From Evident Corporation - Life Sciences 20 May 2020

CELLINK announces partnership with AstraZeneca to provide advanced 3D-bioprinted liver organoids

CELLINK, focused on the development and commercialization of innovative bioprinting technologies and bioinks, announced today that the company will collaborate with AstraZeneca to provide advanced 3D-bioprinted liver organoids for drug discovery purposes in cardiovascular, renal and metabolic diseases.

From CELLINK 15 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

The researcher Manel Esteller performs the first massive epigenetic characterization in organoids or 3D cancer cultures and makes the data available to the research community to facilitate new findings on tumor development and progression.

15 May 2020

A deep look into hormone-producing cells of the gut

Researchers from the Hubrecht Institute and Utrecht University generated an in-depth description of the human hormone-producing cells of the gut, in a large collaborative effort with other research teams. The results are presented in the scientific journal Cell on the 13th of May.

13 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

Frequently, promising cancer therapies fail when applied to patients in the real clinical setting. This occurs despite many of these new treatments demonstrating promising results at the preclinical stage in the lab.

13 May 2020

Researchers identify new therapeutic target to switch-off cancer stem cells

Tumors are not a uniform mass of cells. Colon cancers bear differentiated-like cells, similar to the functional cells of the intestinal wall, and pluripotent cells--the so-called tumour stem cells.

13 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020

Breakthrough study could revolutionize cancer treatment

Scientists have used 3D models to break down the DNA behavior of cancer cells, in a breakthrough new study which could revolutionize treatment for the disease.

10 May 2020

SARS-CoV-2 readily infects human intestinal cells in a laboratory model

A new Dutch study available on bioRxiv uses differentiated human small intestinal organoids in vitro to demonstrate that intestinal epithelium supports the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and elicits a strong generic immune response.

27 Apr 2020

UCLA scientists receive awards to pursue treatments and vaccines for COVID-19

Three researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards to pursue treatments and vaccines for COVID-19 from the California Institute for Regenerative Medicine, the state's stem cell agency.

25 Apr 2020

New therapeutic approach for preserving inflammation-free phases of Crohn's disease

Intestinal stem cell metabolism is facilitated by mitochondria - the in-cell power plants. Chronic inflammation processes inhibit the cells' metabolism and lead to functional loss of these stem cells.

15 Apr 2020