Pathophysiology News and Research

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Researchers find link between disrupted energy production and late-onset Alzheimer's disease

A team of investigators from McLean Hospital and Harvard Medical School, led by Kai C. Sonntag, MD, PhD, and Bruce M. Cohen, MD, PhD, has found a connection between disrupted energy production and the development of late-onset Alzheimer's disease (LOAD). The findings appear in the current issue of Scientific Reports.

27 Oct 2017

Study reveals how NET intervention can alleviate stress from traumatic cancer-related memories

Patients diagnosed and treated for a long-term potentially fatal diseases such as cancer, can accumulate distressing and traumatic experiences along the way.

27 Oct 2017

New molecule could become first treatment against chemotherapy-induced neuropathy

IDIBELL Researchers of the Neuro-Oncology Unit of Bellvitge University Hospital - Catalan Institute of Oncology, led by Dr. Jordi Bruna, have successfully tested a new molecule capable of preventing the development of peripheral neuropathy induced by chemotherapy in cancer patients, especially in colon cancer cases, the third most common neoplasm in the world.

24 Oct 2017

Crown Bioscience announces availability of new translational models for obesity and diabetes in Europe

Crown Bioscience, a wholly-owned subsidiary of Crown Bioscience International and a global drug discovery and development services company providing translational platforms to advance oncology, inflammation, cardiovascular and metabolic disease research, announces the availability of their proprietary FATZO model in a European based laboratory.

12 Oct 2017

Cellular messaging mechanism could lead to new way of treating disease

A newly discovered cellular messaging mechanism could lead to a new way to deliver therapeutics to tissues affected by disease, according to a new study from Harvard T.H. Chan School of Public Health.

27 Sep 2017

Study may contribute to genetic understanding of high-altitude adaptation

Many research groups have recently explored human adaptation and successfully identified candidate genes to high altitude living among three major far-flung global populations: Tibetans, Ethiopians and Peruvians.

22 Sep 2017

Researchers identify exosomes as missing link to insulin resistance in type 2 diabetes

Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now.

21 Sep 2017

Could smart vital sign monitoring provide an early warning system for hospitals?

Vital signs have been around for a long period of time. Taking the pulse is probably one of the oldest examinations that doctors have made to assess patients.

21 Sep 2017

Crohn's & Colitis Foundation and Oxford University Press partner to publish Inflammatory Bowels Diseases journal

The Crohn's & Colitis Foundation and Oxford University Press announced today that they have entered into a new partnership to publish the Foundation's journal Inflammatory Bowels Diseases beginning in 2018.

20 Sep 2017

Link between breast cancer and obesity may be more complex than previously thought

Obese women with large bellies may be at risk of developing a different subtype of breast cancer than those with widespread fat accumulation, according to a new study published in The Oncologist. This suggests that the link between breast cancer and obesity may be more complex than previously thought.

18 Sep 2017

MIT study offers new approach to evaluate risk of preterm birth

Up to 18 percent of babies born worldwide arrive before they are full-term, defined as 37 weeks of gestation. About 1 million of those babies do not survive, and those who do can face developmental problems such as impaired vision or hearing, defects in the heart or lungs, or cognitive impairments.

5 Sep 2017

Breastfeeding linked to lower risk of endometriosis

Endometriosis is a chronic and incurable gynecologic disorder that affects approximately 10 percent of women in the United States. Its symptoms can be debilitating and include chronic pelvic pain, painful periods and pain during intercourse.

30 Aug 2017

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

Imaging study identifies brain structural changes linked to physical, mental health in FND patients

An imaging study by Massachusetts General Hospital investigators has identified differences in key brain structures of individuals whose physical or mental health has been most seriously impaired by a common but poorly understood condition called functional neurological disorder (FND).

28 Aug 2017

Researchers uncover evidence linking mental health disorders and disturbances to gut microbiome

Better understanding the gastrointestinal microbiome may help psychiatrists treat mental health disorders such as depression, highlights a review in Frontiers in Psychiatry.

23 Aug 2017

Leading experts come together to discuss clinical, translational applications of mitochondria

The American Physiological Society will host the "Physiological Bioenergetics: Mitochondria from Bench to Bedside" conference August 27–30 in San Diego. The meeting will bring together cross-disciplinary experts who study the mitochondria, which provide the energy to individual cells.

23 Aug 2017

Pathophysiology News and Research

Researchers find link between disrupted energy production and late-onset Alzheimer's disease

Study reveals how NET intervention can alleviate stress from traumatic cancer-related memories

New molecule could become first treatment against chemotherapy-induced neuropathy

Crown Bioscience announces availability of new translational models for obesity and diabetes in Europe

Cellular messaging mechanism could lead to new way of treating disease

Study may contribute to genetic understanding of high-altitude adaptation

Researchers identify exosomes as missing link to insulin resistance in type 2 diabetes

Could smart vital sign monitoring provide an early warning system for hospitals?

Crohn's & Colitis Foundation and Oxford University Press partner to publish Inflammatory Bowels Diseases journal

Link between breast cancer and obesity may be more complex than previously thought

MIT study offers new approach to evaluate risk of preterm birth

Breastfeeding linked to lower risk of endometriosis

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

Imaging study identifies brain structural changes linked to physical, mental health in FND patients

Researchers uncover evidence linking mental health disorders and disturbances to gut microbiome

Leading experts come together to discuss clinical, translational applications of mitochondria

FDA approves Besponsa – Pfizer’s new drug for rare form of acute lymphoblastic leukemia

CHLA researchers succeed in better defining rare pediatric malignant liver disease

Discovery of new biological pathway involved in pain processing offers hope for new treatments

Researchers identify decreased brain pH levels in mouse models of mental disorders

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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