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Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Researchers discuss the genomic and virological characterization of SARS-CoV-2 variants among unvaccinated and vaccinated U.S military personnel.

16 Feb 2022

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Researchers present a simple and efficient plasmonic-magnetic nanorobot for the detection of SARS-CoV-2 RNA.

16 Feb 2022

Single dose of BNT162b2 vaccine after COVID provides 82% reduction in reinfection risk

Researchers compare the incidence rate of reinfection in convalescent and unvaccinated people to that in recovered and single-dose vaccinated people.

16 Feb 2022

Study confirms that pets can harbor SARS-CoV-2 infection

A new study looks at how dogs and cats within households are susceptible to COVID-19 infection from humans, and whether they act as reservoir species.

16 Feb 2022

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

A new study evaluated the pregnancy outcomes of pregnant women in the third trimester who were infected by SARS-CoV-2 for the detection of the virus in the placenta and different samples of the newborn as well as detection of antibodies in the cord blood.

16 Feb 2022

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

The multiplex detection approach outlined in this study has the potential to address the need to rapidly characterize the phenotype and clinical response to continually emerging SARS-CoV-2 variants as the COVID-19 pandemic continues.

16 Feb 2022

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

In a recent study posted to the medRxiv* preprint server, researchers evaluated if folic acid or methotrexate use impacts the risk of coronavirus disease 2019 (COVID-19) diagnosis or associated mortality in the United Kingdom (UK).

15 Feb 2022

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers select and study an RDV-resistant virus by serial passaging of wild type SARS-CoV-2 in the presence of increasing concentrations of RDV.

15 Feb 2022

Canadian study estimates incidence rate of reinfection in healthcare workers

Researchers from various Canadian institutions document all cases of reinfection discovered during the first year of the project.

15 Feb 2022

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

A new study published demonstrated the in vitro potencies of RDV and GS-441524 through PRA, and nucleoprotein ELISA against SARS-CoV-2 and other VOC/VOIs isolates with specific substitutions in Nsp12.

15 Feb 2022

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

In a new study, a team of researchers demonstrated multiple site-directed mutagenesis as an efficient, easy, and more economically viable alternative to commercial gene synthesis to highlight how specific residues can contribute to the molecular structure and functioning of proteins.

15 Feb 2022

South African population reveal durable protection by prior infection against pre-Omicron variants

A recent study explored the buildup of immunity developed post-SARS-CoV-2 infection in African people and the impact of SARS-CoV-2 Omicron VOC on the COVID-19 pandemic.

15 Feb 2022

Study explores SARS-CoV-2 antibodies in children

Researchers set out to explore how COVID-19 antibody responses persist over time after natural infection in children.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

In a recent study posted to the bioRxiv* preprint server, a team of researchers from Washington, United States, investigated the transmission of viral genetic diversity during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading outbreak among the crew members on a fishing boat.

14 Feb 2022

Polymerase News and Research

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Single dose of BNT162b2 vaccine after COVID provides 82% reduction in reinfection risk

Study confirms that pets can harbor SARS-CoV-2 infection

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Canadian study estimates incidence rate of reinfection in healthcare workers

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

South African population reveal durable protection by prior infection against pre-Omicron variants

Study explores SARS-CoV-2 antibodies in children

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

First survey on Omicron BA.2 in France

RNA capping mechanism of SARS-CoV-2 unveiled

Antihistamines may offer hope for long COVID patients

SpaceX employee study estimates odds ratio for SARS-CoV-2 reinfection

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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