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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Massive proteomics investigation of COVID-19 infection

Massive proteomics investigation of COVID-19 infection

Researchers from Germany and Switzerland revealed functional effects of individual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins on cellular level after infection. They placed the findings into the context of host signaling pathways in order to identify vulnerable parts of the virus amenable to treatment. The study is currently available on the bioRxiv preprint server.

21 Jun 2020

Killifish model helps unravel molecular events that lead to loss of protein homeostasis during brain aging

Killifish model helps unravel molecular events that lead to loss of protein homeostasis during brain aging

Aging is the main risk factor for dementia and Parkinson's disease. As age progresses, toxic protein aggregates pile up in the brain and impair neuronal function.

21 Jun 2020

Computational approach to design peptide-based vaccine against SARS-Cov-2

Computational approach to design peptide-based vaccine against SARS-Cov-2

There are currently no licensed vaccines available for COVID-19. While several antiviral drugs have been tested, none has proved to be completely effective against the disease.

11 Jun 2020

Evosep and Agilent Technologies will collaborate to further improve their robust, high-throughput workflows for proteomics

Evosep and Agilent Technologies will collaborate to further improve their robust, high-throughput workflows for proteomics

Today, at the ASMS 2020 Reboot, Evosep and Agilent Technologies announce their joint efforts to improve robust, high-throughput workflows for clinical research proteomics.

From Agilent Technologies 10 Jun 2020

New EUbOPEN consortium will enable access to research tools to unlock disease biology

New EUbOPEN consortium will enable access to research tools to unlock disease biology

Frankfurt and Ingelheim. Almost twenty years after deciphering the human genome, our understanding of human disease is still far from complete.

8 Jun 2020

High-throughput analysis of blood plasma could help identify biomarkers for ALS

High-throughput analysis of blood plasma could help identify biomarkers for ALS

High-throughput analysis of blood plasma could aid in identification of diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis (ALS), according to research from North Carolina State University.

29 May 2020

Thermo Fisher Scientific acknowledges the winners of 2020 TMT Research Grant Award

Thermo Fisher Scientific acknowledges the winners of 2020 TMT Research Grant Award

Thermo Fisher Scientific, the world leader in serving science, recognizes the winners of the 2020 Thermo Scientific Tandem Mass Tag Research Award.

From Thermo Fisher Scientific Inc. 28 May 2020

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Thermo Fisher Scientific, the world leader in serving science, and Biognosys, a leading developer of next-generation proteomics solutions, announce they are continuing their collaboration to advance data independent acquisition mass spectrometry-based workflows.

From Thermo Fisher Scientific Inc. 28 May 2020

Thermo Fisher Scientific announces license agreement to develop, commercialize deep learning tools for proteomics

Thermo Fisher Scientific announces license agreement to develop, commercialize deep learning tools for proteomics

Thermo Fisher Scientific, the world leader in serving science, and MSAID GmbH, a software company transforming proteomics with deep learning, announce an exclusive license agreement to develop and commercialize deep learning tools for proteomics, making MSAID’s Prosit-derived framework widely accessible to proteomics laboratories.

From Thermo Fisher Scientific Inc. 28 May 2020

New Thermo Scientific Proteome Discoverer 2.5 software strengthens laboratory workflows

New Thermo Scientific Proteome Discoverer 2.5 software strengthens laboratory workflows

Scientists in the life sciences can now benefit from upgrades to a suite of analytical software solutions with new features designed to enhance productivity, confidence and accuracy in numerous fields, including proteomics, food safety and biotherapeutic drug development.

From Thermo Fisher Scientific Inc. 28 May 2020

New high-resolution mass spectrometer expands the proven Thermo Scientific Orbitrap platform

New high-resolution mass spectrometer expands the proven Thermo Scientific Orbitrap platform

A new generation, high resolution mass spectrometer (MS) is designed to give proteomics, metabolomics, biopharmaceutical characterization and small-molecule scientists the analytical performance required for research and high-throughput analyses.

From Thermo Fisher Scientific Inc. 28 May 2020

Study could help identify more targeted treatments for ovarian cancer

Study could help identify more targeted treatments for ovarian cancer

The rogue cellular engine that drives a majority of ovarian cancers remains frustratingly difficult to disable. A new study comparing cancerous tissue with normal fallopian tube samples advances important insights about this machinery and confirms biological hallmarks of survival.

20 May 2020

Potential targets discovered for COVID-19 therapy

Potential targets discovered for COVID-19 therapy

A team of biochemists and virologists at Goethe University and the Frankfurt University Hospital were able to observe how human cells change upon infection with SARS-CoV-2, the virus causing COVID-19 in people.

14 May 2020

A 'multi-omics' approach to the development of drugs against COVID-19

A 'multi-omics' approach to the development of drugs against COVID-19

A new study published on the preprint server medRxiv* in May 2020 reports a multi-omics approach that could make it easier to develop drugs that are effective against COVID-19.

12 May 2020

Bone proteomics could estimate the time of death for corpses found in water

Bone proteomics could estimate the time of death for corpses found in water

When a dead body is found, one of the first things a forensic pathologist tries to do is estimate the time of death.

29 Apr 2020

Gustave Roussy and Biognosys Announce Partnership

Gustave Roussy and Biognosys Announce Partnership

The severe pneumonitis in patients infected by SARS-Cov-2 requires prolonged treatment in intensive care units with mechanical ventilation.

From Biognosys 28 Apr 2020

World's largest protein connection map reveals cell workings

World's largest protein connection map reveals cell workings

The human body is comprised of billions of cells. Yet it functions and grows as a single organism, because of trillions of interactions that help various cells recognize and respond to each other via different molecules on their surface or inside the cells. Now, a new study published in the journal Nature in April 2020 describes the first-ever interactome map, to help distinguish healthy interactions and disease-producing ones.

8 Apr 2020

Combining Improved Ion Usage Efficiency with Data Independent Acquisition to Quantify Proteomes

Combining Improved Ion Usage Efficiency with Data Independent Acquisition to Quantify Proteomes

In this interview, Dr. Ben Collins, Reader from the School of Biological Sciences, Queen’s University Belfast talks to News-Medical Life Sciences about his research and work into diaPASEF workflow.

From Bruker Life Sciences Mass Spectrometry 8 Apr 2020

Investigating Human Disease with Mass Spectrometry-based Proteomics

Investigating Human Disease with Mass Spectrometry-based Proteomics

Dr. Andrew Webb describes how his lab uses mass spectrometry-based techniques to understand the role of post-translational modifications in human disease.

From Bruker Life Sciences Mass Spectrometry 3 Apr 2020

Nanoneedle technology licensed for early detection of disease, biomarker discovery

Nanoneedle technology licensed for early detection of disease, biomarker discovery

A Boston-based startup company, NanoMosaic LLC, intends to commercialize a high-throughput, high-sensitivity platform for analyte detection developed at Harvard University.

2 Apr 2020

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