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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study identifies mechanisms that underlie olfactory symptoms of COVID-19

A new study of human olfactory cells has revealed that viral invasion of supportive cells in the nasal cavity might be driving the loss of smell seen in some patients with COVID-19.

25 Jul 2020

Sputum testing detects COVID-19 virus at higher rates than other methods

Early and accurate detection is critical for preventing the spread of COVID-19 and providing appropriate care for patients.

24 Jul 2020

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

An experimental messenger RNA (mRNA)-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits protective immune responses in mice and non-human primates, researchers report on July 23rd in the journal Cell.

24 Jul 2020

Bacteriophages may play a key role in treating prosthetic joint infections

Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research.

24 Jul 2020

Study shows how protective T cells become pathogenic in atherosclerosis

High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are still at risk.

24 Jul 2020

Scientists discover how coronavirus enters cells without encountering immune system resistance

With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in.

24 Jul 2020

Pets show antibodies to SARS-CoV-2 in Italian study

A study shows that reverse transmission of SARS-CoV-2 is probable, with 3-4% of pets showing antibodies to the infection, though no virus was recovered.

24 Jul 2020

New model may explain why certain cancer cells are resistant to therapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures.

24 Jul 2020

New genome-editing technologies can help understand disease-associated genetic mutations

New genome-editing technologies developed by researchers in J. Keith Joung's laboratory at the Massachusetts General Hospital (MGH) have the potential to help understand disease-associated genetic mutations that are based on C-to-G (cytosine to guanine) single base changes.

24 Jul 2020

Study estimates the past and present burden of viral hepatitis through blood transfusions

What is the incidence of viral hepatitis caused by blood transfusions before and after Sweden introduced screening of blood in the early 1990s? In an article published in Eurosurveillance ahead of World Hepatitis Day on 28 July, the authors also try to estimate how many people of those who were infected with hepatitis B and C through blood transfusion still live with undiagnosed hepatitis.

23 Jul 2020

Epigenomic modifications play key role in the development of lung tumors

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

23 Jul 2020

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

In a new bioRxiv study, authors identified a isoform of ACE2 (designated as deltaACE2 or dACE2) receptor, shown to be induced in various human cell types.

23 Jul 2020

New article sheds light on challenges faced by vaccine developers

With the global pandemic still in full swing, scientists are working to develop a vaccine in record time. While everyone wants an effective vaccine, they don't all agree on how to get there and what "effective" really means.

23 Jul 2020

New regulatory mechanism reveals complex intricacies of plant immune responses

To ensure survival, living organisms are equipped with defensive systems that detect threats and respond with effective counter measures.

23 Jul 2020

siRNA-based treatment can reduce psoriasis symptoms

Psoriasis, a chronic skin condition that causes itchy, red, scaly patches, afflicts more than 8 million Americans and 125 million people worldwide.

23 Jul 2020

Research could lead to more efficient cellular immunotherapies for advanced cancers

Adoptive cell transfer immunotherapy is one of the most promising new treatments for people with hard-to-treat cancers.

23 Jul 2020

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

NIH leaders create a framework to scale up testing technologies for COVID-19

In a paper in the New England Journal of Medicine, scientific leaders from the National Institutes of Health set forth a framework to increase significantly the number, quality and type of daily tests for detecting SARS-CoV-2, the virus that causes COVID-19, and help reduce inequities for underserved populations that have been disproportionally affected by the disease.

23 Jul 2020

Ashion Analytics and Elevation Oncology form innovative cancer treatment partnership

Ashion Analytics LLC today announced a partnership with Elevation Oncology, a clinical stage biopharmaceutical company, focused on the matching of patients with tumors harboring an NRG1 gene fusion identified using Ashion's proprietary GEM ExTra test with CRESTONE, a registration-directed Phase 2 study sponsored by Elevation Oncology.

23 Jul 2020

Vesigen Therapeutics to develop and commercialize novel drug-delivery technologies

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

RNA News and Research

Further Reading

Study identifies mechanisms that underlie olfactory symptoms of COVID-19

Sputum testing detects COVID-19 virus at higher rates than other methods

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

Bacteriophages may play a key role in treating prosthetic joint infections

Study shows how protective T cells become pathogenic in atherosclerosis

Scientists discover how coronavirus enters cells without encountering immune system resistance

Pets show antibodies to SARS-CoV-2 in Italian study

New model may explain why certain cancer cells are resistant to therapy

New genome-editing technologies can help understand disease-associated genetic mutations

Study estimates the past and present burden of viral hepatitis through blood transfusions

Epigenomic modifications play key role in the development of lung tumors

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

New article sheds light on challenges faced by vaccine developers

New regulatory mechanism reveals complex intricacies of plant immune responses

siRNA-based treatment can reduce psoriasis symptoms

Research could lead to more efficient cellular immunotherapies for advanced cancers

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

NIH leaders create a framework to scale up testing technologies for COVID-19

Ashion Analytics and Elevation Oncology form innovative cancer treatment partnership

Vesigen Therapeutics to develop and commercialize novel drug-delivery technologies

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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