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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Causes of hepatitis and potential therapies that may improve care presented in study

Hepatitis, a potentially serious disease caused by a virus that attacks the liver, is a major problem worldwide. Hepatitis A is generally food-borne, while hepatitis B and C spread primarily through parenteral or sexual routes. Hepatitis B and C can be life-long, potentially deadly chronic infections.

19 May 2004

New study of tumor genetics may help to treat patients with head and neck cancer

Head and neck tumors account for more than 40,000 new cancers annually in the United States. The most common of these is squamous cell carcinoma. Prognosis is based largely on location and size of the tumor, and if the cancer has spread, or metastasized, to lymph nodes and distant sites in the body.

19 May 2004

Benitec acquires Avocel to focus on rapid development of hepatitis C therapeutics

Benitec Ltd. today announced the acquisition of Avocel, Inc. of Sunnyvale, CA, a leading RNAi therapeutics company, and the establishment of its wholly-owned US subsidiary, Benitec, Inc. Through the acquisition, Benitec gains its first in-house advanced therapeutic development program using DNA-directed RNAi (ddRNAi) to target the Hepatitis C virus.

18 May 2004

3 people with drug-resistant HIV become first to undergo a new form of gene therapy

The idea is to use a modified form of HIV to deliver an "antisense" gene to the immune cells that HIV infects. This is integrated into the cells' genome, and stays there until a cell is infected. Then it is switched on, and produces RNA complementary to the "sense" RNA encoding a viral protein. In theory, the RNAs should bind together, blocking viral replication.

14 May 2004

Father's sperm packs more than just a fertilizer

The major function of a man's sperm was fertilization, scientists once thought. True, sperm contains the father's chromosomes; but new studies from Wayne State University show that RNAs critically important to early growth of an embryo are also delivered.

13 May 2004

Research uncovers critical pieces of human genome

Researchers have found precisely the same sequences in the genomes of humans, rats, and mice; sequences that are 95 to 99 percent identical to these can be found in the chicken and dog genomes, as well.

6 May 2004

System Biosciences launches siRNA expression libraries to target 8,500 human genes

The siRNA libraries contain 7,500 and 43,800 siRNA template sequences that target 1,500 and 8,500 well-characterized human genes, respectively.

6 May 2004

New insight into the function of RNA helicases

If DNA can be compared to an architect who gets all the glory for designing the building, RNA can be compared to the engineer who often goes unrecognized, but is needed to turn the blueprints into a real three-dimensional, functional and safe structure.

5 May 2004

New hope for advances in treatment methods for AIDS, Alzheimer's and age-related blindness

Pharmaceutical science leaders from the FDA, research institutions and top pharmaceutical companies will gather at the 2004 AAPS National Biotechnology Conference, AAPS' spring annual meeting.

4 May 2004

QIAGEN launches human siRNA library sets

Prime Standard QIA a leading supplier of products and technologies for nucleic acid separation, purification and handling today announced that it has launched a series of off-the-shelf human library siRNA sets, covering a broad gene family selection including kinases, GPCRs, apoptosis related genes, and oncogenes, to name a few.

From QIAGEN Manchester Limited 3 May 2004

A new prognostic marker has shown potential to predict recurrence in certain colon cancer patients

In the study, a team of researchers led by Veridex, LLC, a Johnson & Johnson company, used gene expression profiling to identify the new marker – a 23-gene signature – which may predict disease recurrence in patients initially diagnosed with Dukes' B colon cancer.

29 Apr 2004

Scientists have unraveled the behavior of one key component of bacteria

The researchers studied a mechanism of action they call the "magic spot" – an important regulator of gene expression. They describe their results in the current issue of the journal Cell.

29 Apr 2004

Mystery surrounding ageing, death and cancer is dispelled by new study

Scientists from Cancer Research UK and Breast Cancer Campaign have uncovered the first evidence of an entirely new system for holding the ravages of time at bay.

29 Apr 2004

Lou Gehrig’s disease gene discovered

A gene for a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) has been isolated in families in the United States, Belgium and Austria, the Muscular Dystrophy Association (MDA) announced today.

29 Apr 2004

The world's smallest computer made entirely of biological molecules

The world's smallest computer (around a trillion can fit in a drop of water) might one day go on record again as the tiniest medical kit.

28 Apr 2004

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

Researchers at Duke University have developed a new analytical approach that combines genetic and clinical data to give cancer patients an individualized prognosis of their cancer recurrence. The information could prove critical in deciding how aggressively to treat the disease following surgery.

26 Apr 2004

Overview of West Nile virus before season starts

West Nile virus is a newly emergent virus of the family Flaviviridae, found in both tropical and temperate regions. It mainly infects birds, but is also the cause of a number of conditions in humans, horses, and some other mammals. It is transmitted by bites of infected mosquitoes.

24 Apr 2004

Severe Acute Respiratory Syndrome (SARS) overview

Severe Acute Respiratory Syndrome (SARS) is an atypical form of pneumonia that first appeared in November 2002 in Guangdong Province, China.

24 Apr 2004

Respiratory syncytial virus, a common cold virus, can act as a 'hit and hide' virus

An international team of researchers has discovered that respiratory syncytial virus (RSV), a common cold virus causing bronchiolitis in children, can act as a 'hit and hide' virus. It was thought that the virus could only survive in the body for a few days, but these new results show that the virus can survive for many months or years, perhaps causing long-term effects on health, such as damage to the lungs.

23 Apr 2004

Researchers make millions upon millions of drug-like peptides quickly and efficiently

Two Johns Hopkins scientists have figured out a simple way to make millions upon millions of drug-like peptides quickly and efficiently, overcoming a major hurdle to creating and screening huge "libraries" of these super-short proteins for use in drug development.

23 Apr 2004

RNA News and Research

Further Reading

Causes of hepatitis and potential therapies that may improve care presented in study

New study of tumor genetics may help to treat patients with head and neck cancer

Benitec acquires Avocel to focus on rapid development of hepatitis C therapeutics

3 people with drug-resistant HIV become first to undergo a new form of gene therapy

Father's sperm packs more than just a fertilizer

Research uncovers critical pieces of human genome

System Biosciences launches siRNA expression libraries to target 8,500 human genes

New insight into the function of RNA helicases

New hope for advances in treatment methods for AIDS, Alzheimer's and age-related blindness

QIAGEN launches human siRNA library sets

A new prognostic marker has shown potential to predict recurrence in certain colon cancer patients

Scientists have unraveled the behavior of one key component of bacteria

Mystery surrounding ageing, death and cancer is dispelled by new study

Lou Gehrig’s disease gene discovered

The world's smallest computer made entirely of biological molecules

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

Overview of West Nile virus before season starts

Severe Acute Respiratory Syndrome (SARS) overview

Respiratory syncytial virus, a common cold virus, can act as a 'hit and hide' virus

Researchers make millions upon millions of drug-like peptides quickly and efficiently

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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