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Antibody drugs are not recommended for patients with covid-19, say WHO experts

Antibody drugs are not recommended for patients with covid-19, say WHO experts

The antibody drugs sotrovimab and casirivimab-imdevimab are not recommended for patients with covid-19, says a WHO Guideline Development Group of international experts in The BMJ today.

16 Sep 2022

Efficacy and safety of monoclonal antibodies against SARS-CoV-2 during pregnancy

Efficacy and safety of monoclonal antibodies against SARS-CoV-2 during pregnancy

In an article published in the journal Expert Opinion on Drug Safety, scientists have described the safety and efficacy profiles of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monoclonal antibodies in pregnant women with coronavirus disease 2019 (COVID-19).

13 Sep 2022

Saline nasal irrigation after COVID-19 diagnosis reduces hospitalization

Saline nasal irrigation after COVID-19 diagnosis reduces hospitalization

Starting twice daily flushing of the mucus-lined nasal cavity with a mild saline solution soon after testing positive for COVID-19 can significantly reduce hospitalization and death, investigators report.

13 Sep 2022

COVID-19 drugs persist through wastewater treatment, may negatively affect aquatic organisms

COVID-19 drugs persist through wastewater treatment, may negatively affect aquatic organisms

Certain drugs used to treat COVID-19 patients -; including remdesivir, dexamethasone and antibiotics for associated bacterial infections -; persist through wastewater treatment and may occur in waterways at levels high enough to negatively affect aquatic organisms, according to a new study led by researchers at Penn State.

12 Sep 2022

Researchers produce high-resolution crystal structure of enzyme critical to SARS-CoV-2 survival

Researchers produce high-resolution crystal structure of enzyme critical to SARS-CoV-2 survival

A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19.

9 Sep 2022

What is currently known about the mechanism and treatments of long COVID?

What is currently known about the mechanism and treatments of long COVID?

The current understanding of the mechanisms underlying long COVID or post-acute sequelae of COVID and potential treatment methods that show promise in long COVID management.

6 Sep 2022

Auranofin inhibits SARS-CoV-2 replication

Auranofin inhibits SARS-CoV-2 replication

In a new ISCIENCE journal study, scientists identified an FDA-approved NF-κB inhibitor, Auranofin, which can also control inflammation.

6 Sep 2022

SARS-CoV-2 nucleocapsid antigen levels and patient outcomes

SARS-CoV-2 nucleocapsid antigen levels and patient outcomes

In a new study, researchers assessed the correlation between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) antigen levels and hospitalized patient outcomes.

31 Aug 2022

SARS-CoV-2 antigen levels associated with COVID-19 severity and other clinical outcomes

SARS-CoV-2 antigen levels associated with COVID-19 severity and other clinical outcomes

The amount of SARS-CoV-2 antigen measured in the blood of patients hospitalized with COVID-19 is associated with illness severity and other clinical outcomes, according to a new study published in the Annals of Internal Medicine.

29 Aug 2022

What is the association between T lymphocyte-mediated immune responses and COVID-19 severity?

What is the association between T lymphocyte-mediated immune responses and COVID-19 severity?

Researchers examined the relationship between cell-mediated or T lymphocyte-mediated immunity and SARS-CoV-2 infection severity.

25 Aug 2022

What is the prevalence of COVID-associated neurologic complications in hospitalized US children?

What is the prevalence of COVID-associated neurologic complications in hospitalized US children?

Researchers assessed the prevalence of neurologic complications in children hospitalized with COVID-19.

16 Aug 2022

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

In newly released research, scientists assessed the cardiac effects of remdesivir.

12 Aug 2022

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Researchers demonstrated multiple routes SARS-CoV-2 might take to develop high-level resistance to nirmatrelvir, an oral antiviral targeting the 3C-like protease (3CLpro) of SARS-CoV-2.

11 Aug 2022

The features of the newly emerging SARS-CoV-2 Omicron BA.2.75 subvariant

The features of the newly emerging SARS-CoV-2 Omicron BA.2.75 subvariant

Researchers evaluated all the features, especially the antigenic properties and transmission potential of SARS-CoV-2 Omicron sub-variant BA.2.75.

10 Aug 2022

The impact of cold agglutinin syndrome on clinical presentations in COVID-19

The impact of cold agglutinin syndrome on clinical presentations in COVID-19

Researchers presented two cases to highlight the impact of cold agglutinin syndrome on clinical presentations in COVID-19.

8 Aug 2022

Researchers identify new therapies that could provide better protection against future COVID-19 variants

Researchers identify new therapies that could provide better protection against future COVID-19 variants

Researchers from the University of Kent in Canterbury, UK and the Goethe-University in Frankfurt am Main have identified new therapies for COVID-19 that could provide better protection against future variants and outbreaks.

8 Aug 2022

Hemopurifier containing Galanthus nivalis resin removes SARS-CoV-2 variants

Hemopurifier containing Galanthus nivalis resin removes SARS-CoV-2 variants

Scientists hypothesize that the GNA affinity resin would remain effective against SARS-CoV-2 variants.

2 Aug 2022

Is cannabidiol effective against COVID-19?

Is cannabidiol effective against COVID-19?

A new study discusses the utility of CBD in treating the inflammatory symptoms of COVID-19

31 Jul 2022

The effects of CBD in the treatment of COVID-19–related inflammatory symptoms

The effects of CBD in the treatment of COVID-19–related inflammatory symptoms

Researchers reviewed the effectiveness of cannabidiol in treating COVID-19 inflammatory-related symptoms.

28 Jul 2022

Study confirms efficacy of molnupiravir against COVID in a real-life cohort

Study confirms efficacy of molnupiravir against COVID in a real-life cohort

Researchers report the efficacy and safety of molnupiravir in treating COVID-19.

26 Jul 2022

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