Short Chain Fatty Acids News and Research

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Butyrate and propionate are two important short-chain fatty acids (SCFAs) produced in the human gut. They have been shown to have significant immune system effects in the intestinal mucosa, by inducing the differentiation of T-regulatory cells via inhibition of histone deacetylase (HDAC). This enzyme keeps chromatin from unwinding and, therefore, inhibits gene transcription.

Blood cell damage in COVID-19 may compromise oxygen transport

Researchers in the U.S. have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may alter key protein structures on red blood cells and compromise the transport and delivery of oxygen in patients with coronavirus disease 2019 (COVID-19).

1 Jul 2020

Common food additive alters gut microbiota in mice

A common food additive, recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to research led by a University of Massachusetts Amherst food scientist.

25 Jun 2020

Study finds overabundance of opportunistic pathogens in the guts of persons with Parkinson's

Parkinson's disease is a common, progressive and debilitating neurodegenerative disease. It currently cannot be prevented or cured.

18 Jun 2020

High-salt diet may modulate the gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

9 Jun 2020

Study: Early introduction of solid foods may predispose infants to obesity

Infants who were started on solid foods at or before three months of age showed changes in the levels of gut bacteria and bacterial byproducts, called short-chain fatty acids, measured in their stool samples, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

1 Apr 2020

Using 'organs-on-a-chip' to study chronic inflammatory diseases

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.

18 Mar 2020

Diet influences multiple sclerosis disease course

The short-chain fatty acid propionic acid influences the intestine-mediated immune regulation in people with multiple sclerosis (MS).

11 Mar 2020

Research opens up new prospects for prevention and treatment of bacterial pneumonia

Researchers from the Lille Centre for Infection and Immunity, INRAE and from Brazilian (Belo Horizonte), Scottish (Glasgow) and Danish (Copenhagen) laboratories have shown for the first time in mice that perturbation of the gut microbiota caused by the influenza virus favors secondary bacterial superinfection.

3 Mar 2020

Mediterranean diet promotes healthy aging with healthier gut microbiome

A new study published online in the journal Gut in February 2020 reports the striking health-promoting effects of switching to a Mediterranean diet for just one year. The results were due to an increase in the health and number of gut bacteria that favor a healthy diet.

17 Feb 2020

Genomic sequencing technique helps understand gut microbiota one cell at a time

A population of microorganisms living in our intestine, known as the gut microbiota, plays a crucial role in controlling our metabolism and reducing the risk of conditions such as obesity and diabetes.

9 Feb 2020

Short-term increases in sugar consumption could raise risk of inflammatory bowel disease

Short-term increases in sugar consumption could increase the risk of inflammatory bowel disease and have a significant impact on our health, a new study out of the University of Alberta suggests.

14 Nov 2019

Bacteriophages could treat E. coli without damaging the gut, new study says

Researchers in the US have developed a new therapy that uses a unique bacteriophage to treat E. coli infections.

13 Nov 2019

Healthiest gut bacteria with plant-based or Mediterranean diet

A new study shows that specific foods that are supplied by either a plant-based or a Mediterranean-type diet can protect the gut against inflammatory disorders, by selectively promoting the growth of anti-inflammatory bacteria.

21 Oct 2019

Prehistoric baby bottles: evidence animal milk fed to prehistoric babies

A new study shows that infants in Bronze and Iron Age communities were fed milk using feeding vessels of clay. This report, appearing on September 25, 2019, in the journal Nature, shows the important place that animal milk has played in human food for thousands of years.

26 Sep 2019

A vegan diet could boost gut microbes that aid weight loss

Switching to a vegan diet could help people lose nearly one pound in weight every week and significantly reduce their risk for diabetes, say researchers.

18 Sep 2019

Gut bacteria linked to stronger muscles in older people

The gut bacteria are related to muscle mass and physical function, in a relationship called the gut-muscle axis, which has been studied in mouse models and in young adults. A new study looks at the GMA in older adults for the first time.

18 Sep 2019

Plant-based diet could heal your rheumatoid arthritis

According to the latest review, adopting a plant-based diet could well relieve the swollen joints and pain of rheumatoid arthritis (RA).

13 Sep 2019

Remodeling unhealthful gut microbiomes with the help of synthetic peptides

You are what you eat -; right down to the microbiome living in your gut. Diet can affect which microbes are in the intestinal tract, and research has shown that harmful gut microbiome changes can lead to illnesses such as heart disease, obesity and cancer.

27 Aug 2019

Chemicals produced by gut microbiome could help identify children at risk of organ failure

Chemicals produced by healthy bacteria could be used to assess the health of the gut microbiome and help identify critically-ill children at greatest risk of organ failure, a study published in Critical Care Medicine has found.

14 Jun 2019

Coffee helps develop healthy gut microbes and aids bowel movements

There has been anecdotal evidence that coffee drinkers swear by their morning cup for normal morning bowel movements. A new study from researchers in Texas has shown that coffee indeed helps in bowel movements and also improves the gut microbe population.

20 May 2019