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MD Anderson announces collaborative alliance with Turning Point Therapeutics to advance new treatment options for cancer patients

The University of Texas MD Anderson Cancer Center and Turning Point Therapeutics, Inc., today announced a strategic research and development alliance to expand the evaluation of two of Turning Point's investigational small molecules focusing on precision medicine targets well known in oncology.

24 Jun 2022

New potato processing technique slows starch digestion to avoid blood sugar spikes

Researchers announced early tests of a new potato processing technique designed to make our bodies digest potato starch more slowly.

14 Jun 2022

New molecule kills a broad spectrum of hard-to-treat cancers

A new molecule synthesized by a University of Texas at Dallas researcher kills a broad spectrum of hard-to-treat cancers, including triple-negative breast cancer, by exploiting a weakness in cells not previously targeted by other drugs.

10 Jun 2022

De novo-designed mini-protein against SARS-CoV-2

Researchers characterized truncated forms of LCB1, a de novo-designed mini-protein, against SARS-CoV-2.

7 Jun 2022

New fluorogenic probe could quickly detect the presence of influenza A virus

The influenza A virus, which is responsible for seasonal flu outbreaks, is also the only influenza virus that has previously caused flu pandemics.

6 Jun 2022

UCLA researchers identify a method to make tumors susceptible to immune attack

One powerful way cancer cells defend against tumor-killing immune cells is to load up their cell surface with a protein known as PD-L1. Now a team of UCLA Jonsson Comprehensive Cancer Center researchers led by Roger S. Lo, MD, PhD, has identified a method to degrade tumor cell-surface PD-L1, thereby making tumors susceptible to immune attack.

31 May 2022

Scientists discover how immune proteins defend plants against invading microorganisms

Scientists from the Max Planck Institute for Plant Breeding Research and the University of Cologne, Germany, have discovered a novel biochemical mechanism explaining how immune proteins defend plants against invading microorganisms.

20 May 2022

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19.

20 May 2022

Researchers discover potential treatment approach for advanced uveal melanoma

An international team of researchers led by University College Dublin (UCD) have uncovered a potential treatment approach for advanced uveal melanoma (UM), a type of cancer that effects the eye.

19 May 2022

Prenatal choline supplementation makes essential nutrient available for fetal development

The nutrient choline – shown to have long-term benefits for children whose mothers consume it during pregnancy – also helps the body more efficiently use an omega 3 fatty acid that is essential for fetal brain, cognition and vision development, a new study finds.

18 May 2022

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded approximately $577 million to establish nine Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern.

18 May 2022

Emerging DNA-based sensors are promising tools for food safety

In a recent study published in the journal TrAC Trends in Analytical Chemistry, researchers discussed the current trends, challenges, and future of the deoxyribonucleic acid (DNA)-based sensors in real-time and rapid food contaminants analysis.

18 May 2022

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

In a recent study published in the journal Molecular Therapy, researchers identified Bifonazole, an imidazole-based antifungal agent, to have potent activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using high-throughput screening of small molecules.

12 May 2022

Biomarkers in the blood can indicate the seriousness of head trauma

A simple blood sample to diagnose patients with traumatic brain injury - an innovation enabled by researchers at örebro University.

10 May 2022

Doctoral students explore alternative methods for detecting skin cancer

An early diagnosis is crucial to be able to treat skin cancer before it spreads. But are there simpler methods that do not require taking a traditional tissue sample? Doctoral students from Malmö University have tested and explored various alternative methods with promising results.

6 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

Uncovering a new molecule that shows potential as antidote for carbon monoxide poisoning

Carbon monoxide is an odorless and colorless gas made when fossil fuels burn incompletely. It's also a silent killer.

29 Apr 2022

New insights could lead to better treatments for Dravet syndrome and related conditions

Children with Dravet syndrome, a severe form of epilepsy that begins in infancy, experience seizures, usually for their entire life.

27 Apr 2022

Texas A&M AgriLife scientists receive grant to fight pesticide-resistant cattle fever ticks

Two projects by Texas A&M AgriLife Research scientists aim to protect the U.S. cattle industry from the emerging threat of pesticide-resistant cattle fever ticks.

21 Apr 2022

New insight into SARS-CoV-2 main protease opens door to new viral inhibitors

A recent study has revealed a full cycle of substrate cleavage for the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – providing, in turn, a steadfast foundation for developing potent new viral inhibitors. The paper was published in the journal Proceedings of the National Academy of Sciences (PNAS).

20 Apr 2022

Small Molecules News and Research

MD Anderson announces collaborative alliance with Turning Point Therapeutics to advance new treatment options for cancer patients

New potato processing technique slows starch digestion to avoid blood sugar spikes

New molecule kills a broad spectrum of hard-to-treat cancers

De novo-designed mini-protein against SARS-CoV-2

New fluorogenic probe could quickly detect the presence of influenza A virus

UCLA researchers identify a method to make tumors susceptible to immune attack

Scientists discover how immune proteins defend plants against invading microorganisms

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

Researchers discover potential treatment approach for advanced uveal melanoma

Prenatal choline supplementation makes essential nutrient available for fetal development

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

Emerging DNA-based sensors are promising tools for food safety

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

Biomarkers in the blood can indicate the seriousness of head trauma

Doctoral students explore alternative methods for detecting skin cancer

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Uncovering a new molecule that shows potential as antidote for carbon monoxide poisoning

New insights could lead to better treatments for Dravet syndrome and related conditions

Texas A&M AgriLife scientists receive grant to fight pesticide-resistant cattle fever ticks

New insight into SARS-CoV-2 main protease opens door to new viral inhibitors

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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