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Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

New drug candidate designed at the atomic level could help halt emerging SARS-CoV-2 variants

Although COVID-19 has faded from the headlines, SARS-CoV-2 – the coronavirus behind the pandemic – is still rampantly infecting people around the world.

14 Mar 2024

LAG-3 protein structure may be the key to unlocking new cancer treatments

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could enable the development of new cancer treatments.

11 Mar 2024

Study reveals surge of a neural-specific protein as the earliest-yet biomarker for Alzheimer's disease

A surge of a neural-specific protein in the brain is the earliest-yet biomarker for Alzheimer's disease, report University of Illinois Urbana-Champaign researchers studying a mouse model of the disease.

6 Mar 2024

Noninvasive gamma therapy may hold promise for treating chemo brain

Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating -; a condition commonly known as "chemo brain."

6 Mar 2024

Patient mindset training boosts confidence and effectiveness of care teams

A new study from Stanford University, published Jan. 19 in Patient Education and Counseling, evaluates the effectiveness of patient mindset training on provider learning and behavior.

23 Feb 2024

Hand-held biosensor detects breast cancer biomarkers from saliva

Breast cancer is on the rise, but new tools for early detection could save lives.

13 Feb 2024

Why S. aureus vaccines fail: Immune system hijacked by sneaky bacteria

Staphylococcus aureus (SA) is an extremely common bacterial infection; about 30% of people have colonies of SA living in their nose.

16 Jan 2024

Acute hospital at home model shows promise for boosting patient satisfaction and outcomes

Since the Centers for Medicare and Medicaid Services launched the Acute Hospital Care at Home (AHCaH) Waiver in 2020, thousands of patients from across 300 hospitals in 37 states have been treated in their homes.

9 Jan 2024

Isolation fuels firearm purchases for struggling veterans

Low-income U.S. veterans who are experiencing feelings of loneliness are more likely to purchase firearms, according to new research from UTHealth Houston.

26 Dec 2023

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility that light flickering at the frequency of a particular gamma-band brain rhythm could produce meaningful therapeutic effects for people with Alzheimer's disease.

20 Dec 2023

Cumulative loneliness in mid- to later-life may be a risk factor for mortality

Working from well-established research on the detrimental health effects of loneliness, University of Michigan researchers set out to study whether feeling lonely at multiple times through the years leads to more serious illness and higher mortality risk in mid to later life.

13 Dec 2023

MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

Vegan diet improves cardiovascular health in 8 weeks, twin study finds

In a study with 22 pairs of identical twins, Stanford Medicine researchers and their colleagues have found that a vegan diet improves cardiovascular health in as little as eight weeks.

30 Nov 2023

Single injection of novel hydrogel could replace weekly diabetes injections

Materials engineers at Stanford University have developed a novel hydrogel drug delivery system that transforms daily or weekly injections of diabetes and weight control drugs like Ozempic, Mounjaro, Trulicity, Victoza, and others to just once every four months.

22 Nov 2023

AI-based approach uncovers social patterns that impact child health outcomes

A team led by researchers at Weill Cornell Medicine has used an AI-based approach to uncover underlying patterns among the conditions in which people are born, grow, live, work, and age, termed social determinants of health (SDoH), and then linked each pattern to children's health outcomes.

20 Nov 2023

Benzodiazepine prescribing practices for homeless veterans with mental illness

Despite elevated risk for substance use disorder and overdose death in the homeless population, benzodiazepine prescribing for this population has not been examined.

17 Nov 2023

New physical mechanism uncovered for breast cancer invasion

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable.

13 Nov 2023

Stanford chemists uncover new pathway for protein degradation, opening door to new therapeutics

When targeting problem proteins involved in causing or spreading disease, a drug will often clog up a protein's active site so it can't function and wreak havoc.

25 Oct 2023

Diabetes complications linked to increased risk of colorectal cancer recurrence and death

Complications of diabetes can have numerous negative health effects, from impaired vision and nerve damage to kidney dysfunction and heart disease. In an analysis of information on adults with colorectal cancer, patients who also had diabetes-;particularly those with diabetic complications-;faced a higher risk of dying early.

24 Oct 2023