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Twenty-five million Americans suffer from ulcers. An ulcer is a sore or hole in the lining of the stomach or duodenum (the first part of the small intestine). People of any age can get an ulcer and women are affected just as often as men.

Helicobacter pylori (H. pylori) is a bacterium that lives on the lining of the stomach. Although we used to think that spicy food, acid, and stress were the major causes of ulcers, we now know that nine out of ten ulcers are caused by H. pylori. Medicines that reduce stomach acid may make you feel better, but your ulcer may come back. Here's the good news: Since most ulcers are caused by this bacterial infection, they can be cured with the right antibiotics.

Researchers investigate how CBD could play a therapeutic role in oral ulcer

Xingying Qi, West China Hospital of Stomatology, Sichuan University, Chengdu, China, presented the oral session "Cannabidiol Promotes Oral Ulcer Healing by Inactivating CMPK2-Mediated NLRP3 Inflammasome" at the virtual 99th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 50th Annual Meeting of the American Association for Dental Research and the 45th Annual Meeting of the Canadian Association for Dental Research, on July 21-24, 2021.

22 Jul 2021

A low-cost biopolymer dressing to help heal chronic wounds

Tens of millions of patients around the world suffer from persistent and potentially life-threatening wounds. These chronic wounds, which are also a leading cause of amputation, have treatments, but the cost of existing wound dressings can prevent them from reaching people in need.

19 Jul 2021

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

In a recent study published in the journal Pathogens, researchers carried out a molecular docking study for 17 structural analogs prepared from natural maslinic and oleanolic acids and screened them against SARS-CoV-2 main protease. They also experimentally validated the data by determining the half-maximal cytotoxic and inhibitory concentrations of each of the 17 compounds. The researchers investigated whether the compound with antiviral activity affected viral adsorption, replication, or viricidal effect using a plaque infectivity reduction assay.

9 Jun 2021

Low-profile thoracic aortic endograft minimizes complications, increases patient pool

Preliminary results of a clinical trial, presented today at the AATS 101st Annual Meeting, showed that a new, low-profile thoracic aortic endograft is safe and effective in the treatment of descending thoracic aortic aneurysm or penetrating atherosclerotic ulcer (PAU) diseases.

3 May 2021

New stem cell therapy shows promise to prevent diabetes-related amputations

According to the results of a phase 1 clinical trial just published in STEM CELLS Translational Medicine, a new stem cell therapy shows promise of making diabetes-related amputations a thing of the past.

7 Apr 2021

New 'care bundle' can reduce PPE-related facial injuries in frontline COVID-19 healthcare workers

A study has found that a new 'care bundle' can reduce the incidence of facial pressure injuries in frontline COVID-19 healthcare workers caused by the prolonged wearing of Personal Protective Equipment (PPE).

23 Mar 2021

Study reveals new approach for treating diabetic foot ulcers

A discovery involving multiple teams from across Scripps Research has revealed a powerful new approach for treating diabetic foot ulcers, which affect millions of people in the US and often lead to serious complications.

23 Mar 2021

Dandelion extract inhibits SARS-CoV-2 in vitro

An exciting new study describes a specific inhibitor of the SARS-CoV-2 found in an extract of the common dandelion that could provide a new and fruitful avenue of drug research.

23 Mar 2021

World's largest study of genetic factors reveals link between depression and stomach ulcers

University of Queensland researchers have confirmed a link between depression and stomach ulcers, in the world's largest study of genetic factors in peptic ulcer disease.

25 Feb 2021

Cissampelos pareira L. extracts demonstrate anti-SARS-CoV-2 activity in vitro

A team of scientists from India has recently investigated the antiviral potency of a traditional medicinal plant Cissampelos pareira L. in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The findings reveal that both whole-plant extracts and bioactive compounds can inhibit SARS-CoV-2 replication by modulating estrogen receptor 1 (ESR1) activity.

21 Feb 2021

Regular walnut intake may help protect against negative outcomes associated with H. pylori infection

A new animal study, published in the Journal of Clinical Biochemistry and Nutrition, suggests regular walnut consumption may be a promising intervention for reducing negative outcomes associated with Helicobacter pylori (H. pylori) infection, a widespread bacterial infection that affects more than half of the world's population.

9 Feb 2021

Pharmacogenetic tests can benefit four million UK patients annually

Four million UK patients could benefit annually from genetic testing before being prescribed common medicines, according to new research from the University of East Anglia (UEA) in collaboration with Boots UK and Leiden University (Netherlands).

29 Jan 2021

World Health Organization, Sanofi sign new agreement to eliminate neglected tropical diseases

The World Health Organization (WHO) and Sanofi – one of the world's leading pharmaceutical companies – have signed a new agreement for donations of medicines to sustain specific efforts to eliminate neglected tropical diseases (NTDs).

15 Dec 2020

Nearly 70% of diabetic patients in Indonesia experience disease management difficulties, study finds

Researchers from the Fatmawati General Hospital, Indonesia, recently determined the difficulties in diabetes management and how it impacts diabetes morbidity in Indonesia during the COVID-19 pandemic.

7 Dec 2020

New global guidelines issued for pressure ulcer prevention in hospitalized patients

The treatment of COVID-19 patients in intensive care places great demands on healthcare professionals and on the care given.

30 Nov 2020

Study reveals new therapeutic approach for superbug infections

A research team led by Professor Hongzhe SUN, Chair Professor from the Department of Chemistry, Faculty of Science, in collaboration with Dr Pak-Leung HO, Director of the HKU Carol Yu Centre for Infection from the Department of Microbiology, Li Ka Shing Faculty of Medicine.

5 Nov 2020

Illustrations by Nigerian artist kickstart debate on neglected tropical disease

Illustrations by a local artist in Nigeria are helping health workers and policy makers understand what it's really like to live with a neglected tropical disease (NTD).

5 Nov 2020

Research finds increase in risky sexual behavior and STIs despite COVID-19 pandemic

New research launched at the 29th EADV Congress, EADV Virtual, has found that despite the COVID-19 (SARS-CoV-2) lockdown restrictions, diagnosis of sexually transmitted infections (STIs), including gonorrhoea, secondary syphilis and mycoplasma genitalium (MG), have increased.

2 Nov 2020

Aspirin use associated with reduced mortality risk in hospitalized COVID-19 patients

Hospitalized COVID-19 patients who were taking a daily low-dose aspirin to protect against cardiovascular disease had a significantly lower risk of complications and death compared to those who were not taking aspirin, according to a new study led by researchers at the University of Maryland School of Medicine.

22 Oct 2020

Scientists discover a novel antiviral strategy for treating COVID-19

A research team led by Professor Hongzhe SUN, Norman & Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, Faculty of Science, and Professor Kwok Yung YUEN, Henry Fok Professor in Infectious Diseases, Department of Microbiology, Li Ka Shing Faculty of Medicine of the University of Hong Kong (HKU), has discovered a novel antiviral strategy for treatment of COVID-19.

16 Oct 2020

Ulcer News and Research

Researchers investigate how CBD could play a therapeutic role in oral ulcer

A low-cost biopolymer dressing to help heal chronic wounds

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

Low-profile thoracic aortic endograft minimizes complications, increases patient pool

New stem cell therapy shows promise to prevent diabetes-related amputations

New 'care bundle' can reduce PPE-related facial injuries in frontline COVID-19 healthcare workers

Study reveals new approach for treating diabetic foot ulcers

Dandelion extract inhibits SARS-CoV-2 in vitro

World's largest study of genetic factors reveals link between depression and stomach ulcers

Cissampelos pareira L. extracts demonstrate anti-SARS-CoV-2 activity in vitro

Regular walnut intake may help protect against negative outcomes associated with H. pylori infection

Pharmacogenetic tests can benefit four million UK patients annually

World Health Organization, Sanofi sign new agreement to eliminate neglected tropical diseases

Nearly 70% of diabetic patients in Indonesia experience disease management difficulties, study finds

New global guidelines issued for pressure ulcer prevention in hospitalized patients

Study reveals new therapeutic approach for superbug infections

Illustrations by Nigerian artist kickstart debate on neglected tropical disease

Research finds increase in risky sexual behavior and STIs despite COVID-19 pandemic

Aspirin use associated with reduced mortality risk in hospitalized COVID-19 patients

Scientists discover a novel antiviral strategy for treating COVID-19

World Brain Day 2021: An interview with Professor Alan Thompson

Preventing lethal blood clots

Curbing COVID-19 through border controls and restricted entry

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