Unattended, representative sampling for a wide range of chemical reactions. Some reactions are difficult to sample—without affecting reaction progression.

Reliable collection of representative samples of oxygen or moisture-sensitive reactions and reactions at sub-ambient temperatures or high pressure is close to impossible. Highly toxic reactions introduce more difficulties. The exclusive, patented EasySampler probe allows the recording and instant quenching of reactions to offer a sample representative of a reaction during sampling.

EasySampler - Automated Sampling System for Chemical Reactions


Sample and quench at reaction conditions—how does it work?

METTLER TOLEDO’s EasySampler is submerged into a reaction, where it stays during the entire period of the experiment. The sample pocket shifts out and is loaded with a sample. When the pocket withdraws, the sample is instantly quenched at reaction conditions. Then, the sample is diluted to a user-defined concentration and is readily available for offline analysis.

How EasySampler Takes Samples


Representative and reproducible samples—from heterogeneous and multiphase reactions

It is difficult to sample reactions with accuracy. Particularly, sampling is challenging for multiphase and heterogeneous reactions. EasySampler performs sampling from the same point in the reactor, into a pocket of fixed volume and incorporates solids. Solids dissolution starts instantly, with the quench and dilution steps, thereby offering dissolved samples to obtain precise, reproducible, and representative analytical information.


Automated and unattended 24/7—never miss a sample again

Sampling long or toxic reactions, or reactions for the Design of Experiments (DoE) studies, can be cumbersome and impossible, resulting in blind spots in data. This usually necessitates repetitive experiments. EasySampler performs sampling, in the same manner, each time and can be programmed for non-stop sampling operations 24/7 to offer data sets for comprehensive reaction insights and enhancing productivity.


Sample preparation—for HPLC-ready concentrations

Following quenching, the liquid handling system dilutes the sample to a user-defined concentration and shifts the sample to a vial, making it available for offline analysis. These steps can be employed for derivatization, thereby reducing sample preparation time and preventing human error.


Eliminate user safety concerns—related to toxic and hazardous chemistries

EasySampler completely automates the sampling process, thereby avoiding manual handling of liquids. This eliminates hazards and enhances operator safety, particularly with:

  • Highly toxic chemistry
  • Hazardous reactions at high temperatures
  • Other dangerous reaction conditions


Faster and improved chemical development—with integrated reactor systems and EasySampler

Plug-and-play integration of RX-10, OptiMax, and EasyMax Advanced with EasySampler enables quicker chemical development. Automatic reactors regulate reaction parameters while performing experiments 24 hours a day.

The addition of EasySampler offers representative samples across the entire course of the reaction and high-quality HPLC data for complete and precise reaction profiles. iControl software manages the EasySampler and reactor system, as well as delivers all experimental data in a single file. Such integrated tools enable researchers to rapidly understand, invent, and make informed decisions so that reactions can be improved in less duration.


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