Limited-time offer! Up to 25% discount*
High-quality images alone are no longer enough in today’s research environment. Researchers need confidence in their results, reproducibility they can trust, and workflows that can scale as scientific questions evolve. From exploratory research to sophisticated 2D and 3D models, meaningful discovery is dependent on imaging and analysis that work in tandem to accelerate insight without increasing complexity.
Meet the ImageXpress™ HCS.ai High-Content Screening System and IN Carta® Image Analysis software.
This unified imaging and analysis platform helps reduce complexity, minimise variability, and provide reliable, decision-ready insights across a wide range of research workflows.
Why the HCS.ai High-Content Screening System and IN Carta Image Analysis software are the right fit for the lab
The ImageXpress HCS.ai System and IN Carta software, developed by a trusted partner with decades of expertise supporting scientific discovery, empowers users to create high-quality, reproducible insights across a wide range of research workflows.
Image excellence
Deliver high-resolution, reproducible images for all users, assays, and sample types. Advanced optical design, intelligent acquisition, and standardised procedures reduce unpredictability and manual intervention, helping every image deliver reliable, decision-ready insight.
Future-proofing
The system is flexible and upgradeable, safeguarding the investment as biology advances. Modular hardware and scalable software configurations support both regular and advanced applications, enabling a seamless transition from exploratory research to advanced 2D and 3D assays without requiring platform replacement.
Ease of use
IN Carta Image Analysis Software and MetaXpress™ Acquire software work together to optimise imaging and analysis procedures. Intuitive, AI-powered tools assist both new and experienced users in performing sophisticated analysis - reducing training time and removing the need for coding or specialised expertise.
Discover the imaging and analysis workflows supported by the HCS.ai System and IN Carta software

Image Credit: Molecular Devices UK Ltd
- Multiplexed fluorescence assays
- AI-based cell classification and morphology analysis
- Neurite outgrowth and neurotoxicity assays
- 2D phenotypic screening
- 3D spheroids and organoids
- Label-free brightfield imaging
- Reporter-based assays
- Live-cell imaging workflows
- Custom phenotypic models
- Cell cycle and proliferation studies
- Immune cell profiling
- High-content toxicity screening
Zoom in, explore, and experience the platform
See how high-content imaging and AI-powered analysis work together in a unified workflow to transform complex cellular images into meaningful, decision-ready insights.
The system features modular configurations designed to support evolving research needs.

Image Credit: Molecular Devices UK Ltd
Source: Molecular Devices UK Ltd
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ImageXpress HCS.ai WIDEFIELD |
ImageXpress HCS.ai CONFOCAL |
ImageXpress HCS.ai ADVANCED |
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Widefield capability |
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2X–60X high NA and 20X–60X ELWD objective options plus a magnification changer option (1X and 1.5X) |
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Water immersion option (20X–60X) |
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Environmental control option (temperature, humidity, CO2, O2) |
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LED illumination, five-colour LED (up to 220 mW per channel) |
Laser illumination, seven-colour laser (up to 800 mW per channel) |
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DAPI, FITC, TRITC, TxRed, Cy5 (+ CFP, YFP as optional) |
DAPI, CFP, FITC, YFP, TRITC, TxRed, Cy5, Cy7 |
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Standard spinning disk confocal: 60 µm pinhole (single), 60 µm pinhole + 50 µm slit (dual) |
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Deep tissue spinning disk: 50 µm pinhole high-resolution and high-sensitivity disk (dual) |
Limited-time offer!
Request a personalised demo and receive up to 25% discount* off the list price of a NEW ImageXpress HCS.ai High-Content Screening System.
*Promotion terms and conditions
The purchase order must reference the promotion code EU-HCS.ai-Promo20-0726. The offer is to purchase the ImageXpressTM HCS.ai High-Content Screening System for up to 25% off the list price. Valid until 27 November, 2026. The offer does not include shipping and handling, installation or training. The offer does not include any other options or accessories. This promotion cannot be combined with any other promotions or discounts. No substitutions or swaps. The discount is not convertible to cash. Promotion is not valid for standing orders. All prices exclude delivery charges and local taxes, which are the customer's responsibility. Purchase orders must be received by 27 November, 2026, and delivery completed by December 18, 2026. This offer is valid only to customers in Europe when buying directly from Molecular Devices. Commercial organisations are excluded from this offer. Delivery terms are FCA (Free Carrier) and the seller’s shipping facility (Incoterms 2010). Offer void where prohibited. All Molecular Devices products are for research use only. Other restrictions may apply. For our full standard terms and conditions of sale, please visit https://www.moleculardevices.com/terms-and-conditions.