Peptide libraries for target screening

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In prominent research fields such as immunotherapy, vaccine development, drug discovery, and proteomics, target screening is frequently carried out using peptide libraries, which are systematic combinations of various peptides.

To assure the success of any study, GenScript provides complete AccuPep QC services, such as TFA Removal, Solubility Testing, Endotoxin Control & Analysis, and others, using their PepHTS™ platform.

Peptide library specifications

Comprehensive solutions for immunology, proteomics, and drug discovery research.

Table 1. Source: GenScript

	Crude Peptide Library (SC1177) Upgraded!		Purified Peptide Library (SC1487)
Length	5-15 AA	16-25 AA	5-25 AA
Purity	Crude	Crude	≥70% to ≥98%
Quantity	1 – 20 mg	1 – 20 mg	1 – 9 mg***
Turnaround time (Business Days)*	9-17 days	15-20 days	15-20 days
Minimum order size	24 peptides		24 peptides
Deliverable format**	Lyophilized peptides in 96-well plate or individual well-labeled vials
Quality documents	MS only or COA, HPLC and MS for each peptide		COA, HPLC and MS for each peptide
Modifications	Comprehensive: biotin, fluorescent dyes, phosphorylation, methylation, acylation, acetylation, unnatural amino acids, and many more

* Turnaround time may be longer for orders over 60 peptides.
** Automated peptide pooling available upon request.
*** For a quantity over 4 mg, please contact our technical manager to get a quotation.

Select preferred peptide libraries by applications

The following study fields are ideal for GenScript’s customized peptide libraries:

Vaccine development
Proteomics
T-cell immunotherapy
Antibody and T-cell epitope mapping
Biological assays
Cancer research

Peptide libraries for target screening

Image Credit: GenScript

For comprehensive guidance on how to choose the best peptide libraries for any particular research project, refer to the Peptide Library Design Guide:

Table 2. Source: GenScript

Applications	Service	Design	Purity
T-cell Immunotherapy	Micro-scale Peptide Library or Standard Peptide Library	Overlapping Library and Truncated Library	Crude or ≥70%
Vaccine Development	Standard Peptide Library	Overlapping Library or Alanine Scanning Library	High Purity (≥90%)
Cancer Research	Standard Peptide Library	Overlapping Library	Crude or ≥70%
Antibody and T-cell Epitope Mapping	Standard Peptide Library	Overlapping Library, Positioning Scanning Library or Truncated Library	Crude or ≥70%
Proteomics	Micro-scale Peptide Library	Overlapping Library	Crude
Biological Assays	Micro-scale Peptide Library or Standard Peptide Library	Overlapping Library or Scrambled Peptide Library	≥70% or higher

Technology and quality

Utilizing the proprietary PepHTS™ Peptide Library Technology, peptide libraries are created and rigorous quality control is performed before delivery to prevent cross-contamination.