Cell Biology

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ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

For more than two decades, University of Alabama at Birmingham researcher Susan Bellis, Ph.D., has studied how the addition of sialic acid to various proteins increases cancer resistance and oncogenicity.

22 Apr 2022

Single-cell atlas of non-hematopoietic cells provides insights into lymphoma stromal biology

Researchers from the University of Tsukuba identify gene expression signatures in different types of lymph nodes cells that play an active role in the development of lymphomas.

21 Apr 2022

Researchers develop a live imaging system to observe collagen synthesis

"Proteins are the building blocks of our body": You have probably heard this phrase before. Proteins are essential to the formation of our body's structures, and their functioning.

21 Apr 2022

New approach successfully differentiates between antibodies against influenza and SARS-CoV-2

A new study shows that it is possible to use the genetic sequences of a person's antibodies to predict what pathogens those antibodies will target.

21 Apr 2022

Cell division crucial for the success of macrophage infiltration

Researchers at ISTA discover a crucial process that enables immune cells to get to where they are needed. Study published in Science.

21 Apr 2022

Novel methods for inferring the movement of brain cells during fetal development

The making of a human brain remains a mostly mysterious process that races from an embryonic neural tube to more than 100 billion interconnected neurons in the brain of a newborn. To achieve this marvel of biological engineering, the developing fetal brain must grow, on average, at a rate of roughly 250,000 nerve cells per minute throughout the course of a pregnancy.

21 Apr 2022

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Despite the success of immunotherapy in helping many people with cancer, the majority of patients still do not respond to these treatments. There is need for continued research.

20 Apr 2022

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Alzheimer's disease is marked by a loss of functional neurons in the brain. But what causes this loss? Through single-cell genome sequencing, researchers at Boston Children's Hospital, Brigham and Women's Hospital, and the Broad Institute show that people with Alzheimer's have an abundance of newly acquired mutations in their neurons - more than people of the same age without Alzheimer's, and enough to disable genes important to brain function.

20 Apr 2022

Lab grown, self-renewing muscle stem cells can repair muscle tissue damage in mice

In proof-of-concept experiments, Johns Hopkins Medicine scientists say they have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice, potentially advancing efforts to treat muscle injuries and muscle-wasting disorders in people.

20 Apr 2022

Cells’ exosomes can be effective vehicles for delivering cancer treatments to tumors

A new study published in Cancer Medicine indicates that exosomes, or small bubbles that transport molecules from one cell to another, can be effective vehicles for delivering cancer treatments to tumors.

20 Apr 2022

New technology enables single-cell sorting based on functional outputs

For nearly 40 years, drugmakers have used genetically engineered cells as tiny drug factories. Such cells can be programmed to secrete compounds that yield drugs used to treat cancer and autoimmune conditions such as arthritis.

20 Apr 2022

High performance microplates for enhanced cell growth and survival

The Sero Krystal™ PDL range of coated microplates from Porvair Sciences set a new benchmark for reproducible cell culture even with challenging cell types.

From Porvair Sciences Limited 20 Apr 2022

Newly identified mechanism explains how fine air pollution particles may cause lung cancer

Scientists have identified a mechanism that explains how fine air pollution particles might cause lung cancer, according to a study published today in eLife.

19 Apr 2022

Immune cell responses to bacteria affect intrinsic excitability of neuronal subtypes differently

A new study reports that immune cell responses to bacteria affect the intrinsic excitability of rat neuronal subtypes differently.

19 Apr 2022

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

19 Apr 2022

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly.

18 Apr 2022

Researchers identify 16 distinct cell populations in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

Two strains of TB bacterium attack the lungs in completely different fashion, study finds

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

18 Apr 2022

Scientists unravel the complex workings of the circadian rhythm in cyanobacteria

Scientists want to increase their understanding of circadian rhythms, those internal 24-hour biological clock cycles of sleeping and waking that occur in organisms, ranging from humans to plants to fungi to bacteria.

18 Apr 2022

Cell Biology

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

Single-cell atlas of non-hematopoietic cells provides insights into lymphoma stromal biology

Researchers develop a live imaging system to observe collagen synthesis

New approach successfully differentiates between antibodies against influenza and SARS-CoV-2

Cell division crucial for the success of macrophage infiltration

Novel methods for inferring the movement of brain cells during fetal development

Newly discovered immune cell "soldier" could be a good target for immunotherapy

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Lab grown, self-renewing muscle stem cells can repair muscle tissue damage in mice

Cells’ exosomes can be effective vehicles for delivering cancer treatments to tumors

New technology enables single-cell sorting based on functional outputs

High performance microplates for enhanced cell growth and survival

Newly identified mechanism explains how fine air pollution particles may cause lung cancer

Immune cell responses to bacteria affect intrinsic excitability of neuronal subtypes differently

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

Using customized 'mini-antibodies' to mitigate chronic inflammation

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Researchers identify 16 distinct cell populations in a key brain region for substance use disorders

Two strains of TB bacterium attack the lungs in completely different fashion, study finds

Scientists unravel the complex workings of the circadian rhythm in cyanobacteria

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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