Cell Biology

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Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

UCLouvain discovery could counter SARS-CoV-2 virus independently of the mutations

Despite the effectiveness of vaccination campaigns worldwide, the threat posed by Covid-19 still exists. First of all, a new SARS-CoV-2 variant could very well emerge that may not respond to current vaccines.

10 May 2022

T cell behavior informs metastatic melanoma outcomes

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why.

9 May 2022

Scientists identify the role of phospholipid in maintaining epithelial cellular adhesion

Cells have certain proteins that help them adhere to each other while covering body surfaces and organs. Loss of these identifying proteins could result in cellular progression towards cancer and, subsequently, metastasis.

9 May 2022

Research opens the door to novel therapies for cancer induced by hedgehog signaling pathway

A research led by Hong Kong University of Science and Technology has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that plays an important role in cancer progression, in mammals, opening the door to novel therapeutic strategies for cancer induced by the hedgehog signaling pathway.

9 May 2022

COVID-19 mortality among elderly may be due to genetically predetermined limit on the immune system

Your immune system's ability to combat COVID-19, like any infection, largely depends on its ability to replicate the immune cells effective at destroying the SARS-CoV-2 virus that causes the disease.

9 May 2022

Researchers confirm the existence of 36-mer cellulose synthase supercomplex in cotton fiber

About 180 billion tons of celluloses are produced by the world's vegetation annually, making this polysaccharide the most abundant biological macromolecule on earth.

6 May 2022

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term includes conditions such as unstable angina and acute myocardial infarction (heart attack)).

6 May 2022

Mitosis in moss plants could be far more similar to animal cell division than previously thought

For a new plant to grow from a seed, cells need to divide numerous times. Daughter cells can each take on different tasks and sometimes vary in size. How plants determine the plane of cell division in this process, known as mitosis, is being researched by Prof. Dr. Ralf Reski and Dr. Elena Kozgunova from the University of Freiburg in a joint effort with Prof. Dr. Gohta Goshima from Nagoya University.

6 May 2022

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

Immune checkpoint inhibitors are widely used to treat a variety of cancers; however, one serious side effect is the onset of type 1 diabetes.

6 May 2022

SARS-CoV-2 develops partial resistance to the antiviral drug remdesivir in cell culture

The virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism.

5 May 2022

Fecal microbiota transplant can reverse hallmarks of aging in mice

In the search for eternal youth, poo transplants may seem like an unlikely way to reverse the aging process.

5 May 2022

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

Mitochondria serve as the main source of energy production in our cells, and endurance exercise is generally known to improve the function of mitochondria.

4 May 2022

New insights into the cellular and molecular mechanisms of absence seizures

Bochum researchers have gained new insights into the cellular and molecular mechanisms of absence seizures and potential therapy options.

4 May 2022

Researchers overcome a major hurdle to reverse hearing loss due to aging

Hearing loss due to aging, noise and certain cancer therapy drugs and antibiotics has been irreversible because scientists have not been able to reprogram existing cells to develop into the outer and inner ear sensory cells -- essential for hearing – once they die.

4 May 2022

Experts develop new method to control gene expression using electrical signals

Researchers have created an improved method for turning genes on and off using electrical signals.

4 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

Using silk proteins for tendon repair

Just mentioning a ruptured Achilles tendon would make anyone wince. Tendon injuries are well known for their lengthy, difficult and often incomplete healing processes.

3 May 2022

Researchers design and engineer artificial photosynthetic life-forms through endosymbiosis

Every plant, animal or other nucleus-containing cell also harbors an array of miniature "organs" that perform essential functions for the cell. In plants, for example, organelles called chloroplasts photosynthesize to generate energy for the organism.

3 May 2022

Researchers discover how Acinetobacter baumannii can survive on hospital surfaces without water

The pathogen Acinetobacter baumannii can survive on hospital surfaces - without water - for months, an ability that has helped it become a leading cause of hospital-acquired infections.

2 May 2022

Cell Biology

Tumors release lactate to force neighboring cells into supporting cancer growth

UCLouvain discovery could counter SARS-CoV-2 virus independently of the mutations

T cell behavior informs metastatic melanoma outcomes

Scientists identify the role of phospholipid in maintaining epithelial cellular adhesion

Research opens the door to novel therapies for cancer induced by hedgehog signaling pathway

COVID-19 mortality among elderly may be due to genetically predetermined limit on the immune system

Researchers confirm the existence of 36-mer cellulose synthase supercomplex in cotton fiber

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Mitosis in moss plants could be far more similar to animal cell division than previously thought

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

SARS-CoV-2 develops partial resistance to the antiviral drug remdesivir in cell culture

Fecal microbiota transplant can reverse hallmarks of aging in mice

Benefits of endurance exercise in primary mitochondrial disease depend on the underlying mutation

New insights into the cellular and molecular mechanisms of absence seizures

Researchers overcome a major hurdle to reverse hearing loss due to aging

Experts develop new method to control gene expression using electrical signals

Researchers create models to study brain metastases that recapitulate the disease

Using silk proteins for tendon repair

Researchers design and engineer artificial photosynthetic life-forms through endosymbiosis

Researchers discover how Acinetobacter baumannii can survive on hospital surfaces without water

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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