Cell Biology

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Researchers discover how Rift Valley fever virus enters cells

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle.

24 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses-;from oxygen deprivation to chemotherapy-;that would kill any ordinary cell.

23 Sep 2021

Study provides novel insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

23 Sep 2021

Bubble and droplet formation theory inspires a framework for engineering living cells

The heady math that describes how bubbles form in a glass of Champagne has inspired a framework for engineering living cells.

23 Sep 2021

Immune cells in the brain join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Adhesive protein facilitates cluster formation in circulating tumor cells

Circulating tumor cells (CTCs) with stem cell features use the adhesive protein ICAM1 to facilitate formation of CTC clusters, which can travel from primary tumors to other organs in the body, according to a Northwestern Medicine study published in Nature Communications.

22 Sep 2021

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Researchers seek to identify the role of hypoxia on red blood cell aging

Red blood cells are the most abundant cell type in blood, carrying oxygen throughout the human body. In blood circulation, they repetitively encounter various levels of oxygen tension.

22 Sep 2021

Study paves the way for development of novel delivery systems to suppress HIV

In a new study supported by the National Institutes of Health, researchers used exosomes, tiny nanoparticles capable of being taken up by cells, to deliver novel protein into the cells of mice infected with HIV. The protein attached to HIVs' genetic material and prevented it from replicating, resulting in reduced levels of HIV in the bone marrow, spleen, and brain.

21 Sep 2021

Researchers provide structural insights into HCV receptor binding and entry

In a new paper published in Nature, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, describe the structure of a key protein on the surface of the hepatitis C virus (HCV) and how it interacts with its receptor found on some human cells.

21 Sep 2021

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Researchers at the University of Liverpool have shown how SARS-CoV-2 viral proteases attack the host cell, and how this can be targeted to stop virus replication in cell culture using existing drugs.

21 Sep 2021

Careful pipetting reduces the stress on cells in culture

Cell viability, defined as the proportion of live cells in a sample, is a fundamental consideration in all cell culture techniques.

From INTEGRA Biosciences 21 Sep 2021

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system.

21 Sep 2021

Differences in DNA methylation could accurately predict progression of liver disease

Findings of a national study led by the Translational Genomics Research Institute, an affiliate of City of Hope, identify potential biomarkers that might eventually be used to diagnose progressive stages of liver disease.

20 Sep 2021

Researchers develop new method to track the development of cancer cells

Changes in individual cancer cells over time may explain why brain tumours develop so differently, and why some cancer cells are resistant to certain treatments.

20 Sep 2021

Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

A large international collaboration led by researchers from the Johns Hopkins Kimmel Cancer Center has identified promising new targets for pancreatic cancer treatment and early diagnosis after examining various aspects of these tumors' genes and proteins.

20 Sep 2021

Cell Biology

Researchers discover how Rift Valley fever virus enters cells

New discovery offers clues to overcoming resistance to cancer therapies

Study provides novel insights into how KLF4 influences gene expression

Bubble and droplet formation theory inspires a framework for engineering living cells

Immune cells in the brain join together to break down toxic proteins more quickly

Adhesive protein facilitates cluster formation in circulating tumor cells

Repeated injury to the epithelial tissue of airways causes "biological aging" of stem cells

Researchers seek to identify the role of hypoxia on red blood cell aging

Study paves the way for development of novel delivery systems to suppress HIV

Researchers provide structural insights into HCV receptor binding and entry

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Careful pipetting reduces the stress on cells in culture

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

Differences in DNA methylation could accurately predict progression of liver disease

Researchers develop new method to track the development of cancer cells

Two proteins work in tandem to build lifelines to cancer cells, study finds

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

New discovery reveals how immune 'sentinel' cells are maintained

Study highlights the usefulness of organoids for basic research into coronaviruses

Researchers discover new mechanism used by a simple yeast cell to acquire its shape

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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