Cell Biology

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Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

In studies in mice, Johns Hopkins Medicine researchers say they have identified a chemical compound that stops the final events in the pathway linked to the death of brain cells in Parkinson's disease.

1 Jun 2022

New findings reveal potential mechanisms for cellular defects in human laminopathies

A Northwestern Medicine study has uncovered distinct roles for major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics, according to findings published in the Proceedings of the National Academy of Sciences.

1 Jun 2022

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

A new University of California, Irvine-led study identifies sex-specific circuits of muscle signaling to other tissues and that the organs and processes muscle impacts are markedly different between males and females.

31 May 2022

Aging does not influence liver renewal, research shows

The liver has a unique ability to regenerate after damage. However, it was unknown whether this ability decreases as we age.

31 May 2022

Researchers discover how a workhorse protein keeps protein production on track

Cells produce proteins like little factories. But if they make too much at the wrong times it can lead to diseases like cancer, so they control production with a process called RNA interference (RNAi).

31 May 2022

Scientists discover a new role for protein complex at the center of Bardet-Biedl syndrome

Scientists have identified a new role for a protein complex at the center of a human genetic disorder called Bardet-Biedl syndrome, or BBS, for which there is currently no cure.

31 May 2022

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Single-cell RNA-sequencing (scRNA-seq) shows which genes are turned on in a cell and what their level of transcription is. This allows in-depth assessment of the biology of individual cells, and detection of changes that may indicate disease.

31 May 2022

Interactive web portal details the extent of splicing events in noncoding sequences

An online tool reveals the extent of gene-restructuring events in noncoding sequences.

30 May 2022

Gene linked to severe learning disabilities plays a key role in cells' response to environmental stress

A gene that has been associated with severe learning disabilities in humans has been found to also play a vital role in cells' response to environmental stress, according to a Duke University study appearing May 24 in the journal Cell Reports.

27 May 2022

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

Research of the laboratories led by Dr. Silvia de Santis and Dr. Santiago Canals, both from the Institute of Neurosciences UMH-CSIC (Alicante, Spain), has made it possible to visualize for the first time and in great detail brain inflammation using diffusion-weighted Magnetic Resonance Imaging.

27 May 2022

T cells can die without rest and maintenance, scientists say

T cells, biology textbooks teach us, are the soldiers of the immune system, constantly on the ready to respond to a variety of threats, from viruses to tumors.

27 May 2022

Researchers identify a gene that plays vital role in the innate human immune system

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body's white blood cells to go on the attack against a foreign presence.

27 May 2022

Research offers entirely new ways to visualize cell membranes

Research from the lab of Matthew Lew at Washington University in St. Louis offers entirely new ways to see the very small.

27 May 2022

Study shows how synchronization contributes to transmission, processing of information in the brain

In the early 20th century scientists began to record brain activity using electrodes attached to the scalp. To their surprise, they saw that brain activity is characterized by slow and rapid ascending and descending signals which were subsequently called "brain waves".

26 May 2022

Researchers focus on how bacterial cells adapt and resist antibiotics

Treatment of severe infections caused by pathogenic bacteria relies on ‘last resort’ antibiotics, but rising resistance by ‘superbugs’ to most clinically approved drugs leaves patients exposed to possible fatalities.

26 May 2022

UCLA researchers discover key molecular mechanism behind memory linking

Our brains rarely record single memories - instead, they store memories into groups so that the recollection of one significant memory triggers the recall of others connected by time.

25 May 2022

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

Investigators have discovered the mechanisms underlying a T-cell receptor's immunosuppressive function, according to a study published Nature Immunology, findings that may provide insight into the development of novel precision therapeutics for chronic diseases, including cancer.

25 May 2022

Researchers identify the genetic causes of three mitochondrial diseases using new approach

When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, and vision problems.

25 May 2022

New imaging approach helps scientists build a complete picture of brain networks

Researchers at the Francis Crick Institute have developed an imaging technique to capture information about the structure and function of brain tissue at subcellular level – a few billionth of a metre, while also capturing information about the surrounding environment.

25 May 2022

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

A research team at the School of Biological Sciences, the University of Hong Kong, has revealed novel cellular and molecular interactions between cancer cells and tumor-associated macrophages that promote peritoneal metastasis of ovarian cancer.

25 May 2022

Cell Biology

Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

New findings reveal potential mechanisms for cellular defects in human laminopathies

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

Aging does not influence liver renewal, research shows

Researchers discover how a workhorse protein keeps protein production on track

Scientists discover a new role for protein complex at the center of Bardet-Biedl syndrome

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Interactive web portal details the extent of splicing events in noncoding sequences

Gene linked to severe learning disabilities plays a key role in cells' response to environmental stress

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

T cells can die without rest and maintenance, scientists say

Researchers identify a gene that plays vital role in the innate human immune system

Research offers entirely new ways to visualize cell membranes

Study shows how synchronization contributes to transmission, processing of information in the brain

Researchers focus on how bacterial cells adapt and resist antibiotics

UCLA researchers discover key molecular mechanism behind memory linking

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

Researchers identify the genetic causes of three mitochondrial diseases using new approach

New imaging approach helps scientists build a complete picture of brain networks

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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