Cell Biology

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Unusual type of thymocyte cells capable of transforming into blood cancer discovered

Dysfunction involving an unusual type of thymocyte cell found in small amounts in every person may be the reason why some people develop a form of leukemia called T-cell acute lymphoblastic leukemia (T-ALL) that affects more than 6,000 Americans each year.

28 Jun 2022

New tissue model helps trace the steps involved in liver regeneration

The human liver has amazing regeneration capabilities: Even if up to 70 percent of it is removed, the remaining tissue can regrow a full-sized liver within months.

27 Jun 2022

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Columbia and MIT researchers are revealing the surprising reasons why cancer cells are often forced to rely on fat imports, a finding that could lead to new ways to understand and slow down tumor growth.

27 Jun 2022

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

More than 62,000 people in the United States will be diagnosed with pancreatic cancer by the end of this year, with the vast majority having a deadly and aggressive subtype known as pancreatic ductal adenocarcinoma (PDA).

27 Jun 2022

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Need another reason to think twice before ordering that extra helping of fries? It could lead to a higher risk of developing liver cancer.

24 Jun 2022

Researchers determine optimal conditions to perform impedance cytometry

Having a good eye for detail is an essential skill for many professions. In particular, biologists use special techniques and advanced technology to analyze individual cells with unprecedented precision.

24 Jun 2022

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult.

24 Jun 2022

"Founder events" that reduced genetic diversity found to be common throughout human history

Human populations have waxed and waned over the millennia, with some cultures exploding and migrating to new areas or new continents, others dropping to such low numbers that their genetic diversity plummeted.

23 Jun 2022

Bacterium discovery helps to solve the puzzle of what factors limit cell size

On sunken leaves in the waters of a Caribbean mangrove swamp, researchers discovered a bacterium that challenges the prevailing view of bacterial cell size; counter to the notion that microbes are only visible with a microscope, this one – named Thiomargarita magnifica – is larger than all other known giant bacteria by ~50-fold, and can be seen by the naked eye, the study's authors say.

23 Jun 2022

Study unveils a precise model for the stinging organelle of starlet sea anemone

Summertime beachgoers are all too familiar with the painful reality of a jellyfish sting. But how do the stinging cells of jellyfish and their coral and sea anemone cousins actually work? New research from the Stowers Institute for Medical Research unveils a precise operational model for the stinging organelle of the starlet sea anemone, Nematostella vectensis.

23 Jun 2022

Researchers model a complex childhood disease on-a-chip

Millions of children in low- and middle-income nations suffer from environmental enteric dysfunction (EED), a chronic inflammatory disease of the intestine that is the second leading cause of death in children under five years old.

23 Jun 2022

Study provides better understanding of the brain pathways that control nausea

Nausea is a bit of a catchall sensation for the human body: the unpleasant sick feeling can hit us as a result of everything from pregnancy or a migraine to eating spoiled food or undergoing chemotherapy.

22 Jun 2022

Disrupting tuft cell development may be a new way to treat deadly lung cancer

Cold Spring Harbor Laboratory Professor Christopher Vakoc's team discovered in 2018 a new type of small-cell lung cancer. The cancer originates from cells known as tuft cells.

22 Jun 2022

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T–cell therapy for treatment of solid tumors.

22 Jun 2022

Study shows molecular details of HIV-1 assembly and viral envelope protein incorporation

Assembly of HIV-1, which causes AIDS, takes place on the inner plasma membrane leaflet of infected cells, a geometric building process that creates hexamers out of trimers of the viral Gag protein, as guided by Gag's N-terminal matrix domain.

21 Jun 2022

Researchers investigate the cell adhesion behavior on spider silk for medical use

Silk has been cultivated for centuries by domesticated silkworms, but it has been difficult to commercially produce spider silk in bulk due to their cannibalistic tendencies.

21 Jun 2022

Protein produced by soft-tissue sarcomas makes immune cells ‘go bad’

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting.

21 Jun 2022

Researchers discover the skin's natural protection from nighttime bacterial invasion in mice

Researchers at Kyoto University have discovered the skin's natural protection from nighttime bacterial invasion in mice, which may provide a basis for eventually developing a drug treatment.

21 Jun 2022

A class of protein-cleaving enzymes suspected to play a role in hereditary brain disease

Similar to Alzheimer's disease, the hereditary disease spinocerebellar ataxia type 17 (SCA17) leads to the destruction of brain nerve cells and the premature death of patients.

21 Jun 2022

Study offers new insight into the growth of blood vessels

Blood vessels must adapt their growth to the nutrients available in their surroundings so that they can keep organs adequately supplied. A team led by Michael Potente has identified two proteins that are important for this process and published their findings in Nature Metabolism.

20 Jun 2022

Cell Biology

Unusual type of thymocyte cells capable of transforming into blood cancer discovered

New tissue model helps trace the steps involved in liver regeneration

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Researchers determine optimal conditions to perform impedance cytometry

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

"Founder events" that reduced genetic diversity found to be common throughout human history

Bacterium discovery helps to solve the puzzle of what factors limit cell size

Study unveils a precise model for the stinging organelle of starlet sea anemone

Researchers model a complex childhood disease on-a-chip

Study provides better understanding of the brain pathways that control nausea

Disrupting tuft cell development may be a new way to treat deadly lung cancer

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Study shows molecular details of HIV-1 assembly and viral envelope protein incorporation

Researchers investigate the cell adhesion behavior on spider silk for medical use

Protein produced by soft-tissue sarcomas makes immune cells ‘go bad’

Researchers discover the skin's natural protection from nighttime bacterial invasion in mice

A class of protein-cleaving enzymes suspected to play a role in hereditary brain disease

Study offers new insight into the growth of blood vessels

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