Cell Biology

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Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Having shown that diet can influence gene expression, science is starting to find out more about how this happens.

15 Jun 2022

Study sheds light on inhibition of awn elongation in sorghum

Over the years, the domestication of grasses like wheat, rice, barley, and sorghum for consumption has resulted in certain modifications to their morphology. One such modification is the partial or complete elimination of the 'awns', which are the bristle- or needle-like appendages extending from the tip of the lemma in grass spikelets.

15 Jun 2022

UIC scientists identify a dynamic duo of cells in lung blood vessels

Scientists at the University of Illinois Chicago have analyzed gene expression data from more than 35,000 blood vessel cells from the lungs of mice and identified two subtypes.

14 Jun 2022

Emory researchers identify key immune cell type that drives the transition from early to late COVID-19

Determining how SARS-CoV-2, the virus causing COVID-19, moves from an early stage of infection, when patients are largely asymptomatic, into a later stage when people may experience life-threatening inflammation in the lungs, is a critical step in understanding how to target and treat the disease more efficiently.

14 Jun 2022

SARS-CoV-2 Omicron breakthrough infection less immunogenic than Delta

Scientists investigate the sequence and dynamics of recalled immune memory in convalescent individuals who have been vaccinated against COVID-19.

14 Jun 2022

Taking valproic acid during pregnancy can cause birth defects, study shows

Valproic acid - a drug used to treat epilepsy, migraine, and bipolar disorder - can cause birth defects when taken during pregnancy.

14 Jun 2022

New protocol can develop safe, efficient pluripotent stem cell-based therapies for macular degeneration

As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems.

14 Jun 2022

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.

14 Jun 2022

OSU researchers study quorum sensing in a gram-negative bacterium that displays social behaviors

Oregon State University scientists have identified proteins that prevent a bacterial cell from becoming misguided by its own messaging, allowing it to instead wait for collective communication from its group.

13 Jun 2022

RNA exosomes play a key role in B cell development, UTSW study suggests

New research from UT Southwestern suggests that RNA exosomes – the cellular machines that degrade old molecules of RNA – play a key role in the development of B cells, which are critical to the immune system's ability to protect against infection.

13 Jun 2022

Study demonstrates a potential way to stimulate the formation of new insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.

13 Jun 2022

Treatment with immunity-boosting protein enhances the function of CAR-T cells in fighting blood cancers

Advances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers.

13 Jun 2022

Evosep One enables robust, high throughput, single cell proteomics

Today, at the 70th Conference on Mass Spectrometry and Allied Topics, Evosep demonstrates new applications for standardization of high throughput single cell proteomics, higher throughput clinical analysis, and improved diabetes monitoring.

From Evosep 13 Jun 2022

New machine learning algorithm finds a gene signature characteristic of tumors

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors.

10 Jun 2022

Stress protein in fibroblasts appears to be an attractive cancer drug target

A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future cancer treatments, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

10 Jun 2022

Naturally-produced antibodies in mothers may enhance infants' immunity against bacterial pathogens

Researchers have known for some time that maternal breast milk provides critical nutrients for newborns, and antibodies from mothers vaccinated against a specific disease-causing bacterium or virus can be transferred via breast milk to babies.

10 Jun 2022

Deciphering the structure of nuclear pore complex piece by piece

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work.

10 Jun 2022

Creating CAR T cells without an immune brake

T cells are usually very good at eliminating diseased cells. But they seem to fail when it comes to tumor cells.

10 Jun 2022

Brain area communication changes over much faster timescales than previously thought

Understanding how brain areas communicate is one of the oldest questions in neuroscience. Researchers at the Sainsbury Wellcome Centre at UCL used causal techniques to uncover how two neocortical areas in the brain communicate with one another and found that their influence on each other changes over much faster-timescales than previously thought.

10 Jun 2022

New, tiny probe for long-lasting and minimally invasive interfacing with neural circuits

Researchers at the University of California San Diego and the Salk Institute for Biological Studies have developed a tiny neural probe that can be implanted for longer time periods to record and stimulate neural activity, while minimizing injury to the surrounding tissue.

9 Jun 2022

Cell Biology

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Study sheds light on inhibition of awn elongation in sorghum

UIC scientists identify a dynamic duo of cells in lung blood vessels

Emory researchers identify key immune cell type that drives the transition from early to late COVID-19

SARS-CoV-2 Omicron breakthrough infection less immunogenic than Delta

Taking valproic acid during pregnancy can cause birth defects, study shows

New protocol can develop safe, efficient pluripotent stem cell-based therapies for macular degeneration

New project seeks to develop a microscopy system for making drug interactions in the liver visible

OSU researchers study quorum sensing in a gram-negative bacterium that displays social behaviors

RNA exosomes play a key role in B cell development, UTSW study suggests

Study demonstrates a potential way to stimulate the formation of new insulin-producing cells

Treatment with immunity-boosting protein enhances the function of CAR-T cells in fighting blood cancers

Evosep One enables robust, high throughput, single cell proteomics

New machine learning algorithm finds a gene signature characteristic of tumors

Stress protein in fibroblasts appears to be an attractive cancer drug target

Naturally-produced antibodies in mothers may enhance infants' immunity against bacterial pathogens

Deciphering the structure of nuclear pore complex piece by piece

Creating CAR T cells without an immune brake

Brain area communication changes over much faster timescales than previously thought

New, tiny probe for long-lasting and minimally invasive interfacing with neural circuits

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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