Cell Biology

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Brown researchers develop an advanced way to isolate single cells from complex tissues

In cancer research, it all comes down to a single cell. Over the last decade, cancer researchers have homed in on the fact that an individual cell from a tumor can be used to perform molecular analyses that reveal important clues about how the cancer developed, how it spreads and how it may be targeted.

14 Jul 2022

Evonik now offers enteric protected ready to fill capsules EUDRACAP® in IPEC-GMP quality

Evonik’s EUDRACAP® enteric easy-to-handle capsules are now globally available produced under IPEC-GMP. Launched last year, EUDRACAP® enteric are functional, ready-to-fill capsules that help pharmaceutical companies bring complex oral drug products to market faster.

From Evonik Health Care 14 Jul 2022

Study describes the evolution of gut microbes causing chronic inflammation and pathologies

Gut microbes have been linked to both good health and the promotion of diseases such as autoimmune disorders, inflammatory bowel diseases, metabolic syndrome, and even neuropsychiatric disorders.

14 Jul 2022

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and well-being.

13 Jul 2022

New high-throughput genomic array offers an in-depth view of the mouse epigenome

A new high-throughput genomic array offers an unprecedented look into the mouse epigenome, giving researchers an in-depth view into the basis of health and disease in a vital model organism.

13 Jul 2022

Researchers discover new stem cell mechanism in the gut

Your gut is a wondrous place. A special layer of cells that coats the insides of your small and large intestines takes in nutrients and water from what you ate while keeping anything bad out of your system.

13 Jul 2022

Study identifies a protein that plays key role in protecting the gastrointestinal tract from inflammation

A protein called Zbtb46, expressed by specialized immune cells, has a major role in protecting the gastrointestinal tract from excessive inflammation, according to a study from researchers at Weill Cornell Medicine.

13 Jul 2022

Study reveals tiny gene fragments as crucial new players in retinal development and vision

Researchers at the Centre for Genomic Regulation in Barcelona reveal that Srrm3 is a master regulator gene crucial for the development of photoreceptors, cells in the back of the retina which capture and process light, sending signals to the brain that enable vision.

13 Jul 2022

MaxCyte signs strategic platform license with LG Chem to advance its allogeneic CAR-T programs

MaxCyte, Inc., a leading commercial cell-engineering company focused on providing enabling platform technologies to advance innovative cell-based research as well as next-generation cell therapeutic discovery, development and commercialization, today announces the signing of a strategic platform license (SPL) with LG Chem Ltd., a globally diversified chemical company established in petrochemical, advanced materials and bio-technology, aiming to create new value for its customers based on science.

From MaxCyte, Inc. 13 Jul 2022

Study reveals a specific metabolic adaptation in some patients with acute myeloid leukemia

An article published in the journal Nature Communications describes a specific metabolic adaptation in some patients with acute myeloid leukemia affected by tandem mutations in the FLT3 gene.

13 Jul 2022

Researchers gain unexpected insights into activation mechanism of flaviviruses

A collaboration between researchers at the Center for Virology of the Medical University of Vienna and the Pasteur Institute in Paris has provided unexpected insights into the atomic interactions of the tick-borne encephalitis (TBE) virus in infected cells.

13 Jul 2022

Ancestral molecule from bacteria-like cells may offer evolutionary insight on sexual reproduction

A study from Karolinska Institutet in Sweden, among others, presents the theory that egg-sperm fusion, a crucial feature of sexual reproduction in plants and animals, may have originated from an ancient form of genetic exchange that involved the fusion of bacteria-like microorganisms called archaea.

12 Jul 2022

Cancer cells can gravitate toward certain mechanical 'sweet spot' environments, study finds

An international team of researchers led by University of Minnesota Twin Cities engineers have found that cancer cells can gravitate toward certain mechanical "sweet spot" environments, providing new insights into how cancer invades the body.

12 Jul 2022

Study offers insight into cancer cell migration and opens new possibilities for stopping it

An international research group has investigated the mechanisms of cell migration and the impact of tissue rigidity on cell positioning and steering. The research sheds light on e.g. cancer cell migration and opens new possibilities for stopping and directing it.

12 Jul 2022

Stinging nettle extract inhibits SARS-CoV-2 cell fusion

In a recent study posted to the bioRxiv* preprint server, researchers at Ghent University and KU Leuven, Belgium, demonstrated that Urtica dioica agglutinin (UDA), a monomeric lectin extracted from stinging nettle rhizomes, inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) cell to cell fusion.

12 Jul 2022

Persistence of SARS-CoV-2 in tissues leads to long COVID

PASC is likely the result of long-term persistence of SARS-CoV-2 in various tissues

11 Jul 2022

Scientists capture a clear picture of the nuclear pore complex using X-rays

Your body is made of close to 100 trillion cells that keep you healthy and alive. Each cell has billions of parts of its own, all of them working in tandem to keep life's processes moving.

11 Jul 2022

DNA must be enormously compressed in sperm cells, study says

If you are moaning once again about your suitcase being far too small as your vacation approaches, you should take human sperm cells as an inspiration.

11 Jul 2022

UT Southwestern researchers reveal the physical mechanism behind a neurological autoimmune disease

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers for the first time have captured images of an autoantibody bound to a nerve cell surface receptor, revealing the physical mechanism behind a neurological autoimmune disease.

11 Jul 2022

Researchers unravel how epithelial cells become invasive and cancerous

Epithelial cells, which line the surfaces and organs of the body, can protect themselves against cancer by removing unhealthy or abnormal cells through a mechanism known as "apical extrusion," where the damaged cells are forcibly removed from the cell layer by the surrounding healthy cells.

11 Jul 2022

Cell Biology

Brown researchers develop an advanced way to isolate single cells from complex tissues

Evonik now offers enteric protected ready to fill capsules EUDRACAP® in IPEC-GMP quality

Study describes the evolution of gut microbes causing chronic inflammation and pathologies

Study describes biochemical pathway that leads to inflammation characteristic of autoimmune diseases

New high-throughput genomic array offers an in-depth view of the mouse epigenome

Researchers discover new stem cell mechanism in the gut

Study identifies a protein that plays key role in protecting the gastrointestinal tract from inflammation

Study reveals tiny gene fragments as crucial new players in retinal development and vision

MaxCyte signs strategic platform license with LG Chem to advance its allogeneic CAR-T programs

Study reveals a specific metabolic adaptation in some patients with acute myeloid leukemia

Researchers gain unexpected insights into activation mechanism of flaviviruses

Ancestral molecule from bacteria-like cells may offer evolutionary insight on sexual reproduction

Cancer cells can gravitate toward certain mechanical 'sweet spot' environments, study finds

Study offers insight into cancer cell migration and opens new possibilities for stopping it

Stinging nettle extract inhibits SARS-CoV-2 cell fusion

Persistence of SARS-CoV-2 in tissues leads to long COVID

Scientists capture a clear picture of the nuclear pore complex using X-rays

DNA must be enormously compressed in sperm cells, study says

UT Southwestern researchers reveal the physical mechanism behind a neurological autoimmune disease

Researchers unravel how epithelial cells become invasive and cancerous

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