Cell Biology

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Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

In the beginning, there was boredom. Following the emergence of cellular life on earth, some 3.5 billion years ago, simple cells lacking a nucleus and other detailed internal structure dominated the planet. Matters would remain largely unchanged in terms of evolutionary development in these so-called prokaryotic cells - the bacteria and archaea - for another billion and a half years.

8 Aug 2022

Researchers develop new method for visualizing single cell protein secretion with stunning resolution

We have recently witnessed the stunning images of distant galaxies revealed by the James Webb telescope, which were previously visible only as blurry spots.

5 Aug 2022

Locusts can differentiate between cancer cells and healthy cells, research shows

Researchers at Michigan State University have shown that locusts can not only "smell" the difference between cancer cells and healthy cells, but they can also distinguish between different cancer cell lines.

5 Aug 2022

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

A research team led by André Marques at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, has uncovered the profound effects of an atypical mode of chromosome arrangement on genome organization and evolution.

4 Aug 2022

KAIST researchers engineer a bacterial strain capable of producing lutein

A research group at KAIST has engineered a bacterial strain capable of producing lutein. The research team applied systems metabolic engineering strategies, including substrate channeling and electron channeling, to enhance the production of lutein in an engineered Escherichia coli strain.

4 Aug 2022

scRNA-seq of SARS-CoV-2 infected lung organoids finds NFKB Inhibitor Alpha increased in infected cells

Researchers develop a genetically modified airway organoid system, which overcomes challenges related to natural variations in ACE2 levels

4 Aug 2022

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Mitochondria are organelles found within most cells, best known for generating the chemical energy required to power cellular functions.

4 Aug 2022

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety of chronic human ailments, including obesity, type 2 diabetes, atherosclerosis, cancer, non-alcoholic fatty liver disease and inflammatory bowel disease.

4 Aug 2022

Scientists develop a novel, highly-efficient sample preparation method for single-cell proteomics

The proteins that make up our cells hold within an entire world of information, which, when unlocked, can give us insights into the origins of many essential biological phenomena.

4 Aug 2022

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

Researchers identify a component in the intestine that plays key role in repairing damaged tissue

Investigators at Cedars-Sinai and the University of California, San Francisco have identified a component in the intestine that plays a critical role in repairing damaged tissue.

4 Aug 2022

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

We are increasingly being exposed to endocrine-disrupting chemicals (EDCs) that interfere with the normal functioning of our hormones. Bisphenol A (BPA) and phthalates, which are widely used in consumer products including plastics, aluminum cans, pharmaceuticals, and cosmetics, are well-known EDCs.

4 Aug 2022

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

A team of researchers at Tohoku University has reported on a novel function of vitamin K, which is generally known for its importance in blood clotting.

4 Aug 2022

Researchers unravel mechanism of action of bacterial Tc toxin in fatal attacks

A harmful and often deadly substance made by bacteria, a bacterial toxin manipulates host cell functions and disrupts vital cell processes in a living organism.

3 Aug 2022

Cold exposure could make it harder for cancer cells to grow, mice study shows

Turning down the thermostat seems to make it harder for cancer cells to grow, according to a study in mice by researchers at Karolinska Institutet in Sweden.

3 Aug 2022

DeNovix launches nuclei counting apps for CellDrop Automated Cell Counters

DeNovix Inc, the manufacturer of the award-winning CellDrop Automated Cell Counter, has developed two dedicated nuclei counting apps capable of differentiating isolated nuclei and intact cells from debris.

From DeNovix Inc. 3 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN Bio Innovations Ltd 3 Aug 2022

Experiments and mathematical modeling help study the role of morphogens in tissue patterning

Morphogens are molecules that travel from biological cell to cell to pattern tissues in the embryo. These molecules are important not only for the embryo during development, but also for the adult during tissue repair.

2 Aug 2022

Novel algorithm provides rich, detailed information on protein location and function within a cell

Humans are good at looking at images and finding patterns or making comparisons. Look at a collection of dog photos, for example, and you can sort them by color, by ear size, by face shape, and so on. But could you compare them quantitatively? And perhaps more intriguingly, could a machine extract meaningful information from images that humans can't?

2 Aug 2022

Neurons show rhythmic activity at different frequencies in the desynchronized state

In the 17th century, the Dutch scientist Christiaan Huygens hanged two of his recently invented pendulum clocks on a wooden beam and observed that as time passed, the clocks aligned their beats.

2 Aug 2022

Cell Biology

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

Researchers develop new method for visualizing single cell protein secretion with stunning resolution

Locusts can differentiate between cancer cells and healthy cells, research shows

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

KAIST researchers engineer a bacterial strain capable of producing lutein

scRNA-seq of SARS-CoV-2 infected lung organoids finds NFKB Inhibitor Alpha increased in infected cells

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Scientists develop a novel, highly-efficient sample preparation method for single-cell proteomics

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

Researchers identify a component in the intestine that plays key role in repairing damaged tissue

Mice study reveals hepatic consequences of exposure to endocrine disrupting chemical mixtures

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

Researchers unravel mechanism of action of bacterial Tc toxin in fatal attacks

Cold exposure could make it harder for cancer cells to grow, mice study shows

DeNovix launches nuclei counting apps for CellDrop Automated Cell Counters

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Experiments and mathematical modeling help study the role of morphogens in tissue patterning

Novel algorithm provides rich, detailed information on protein location and function within a cell

Neurons show rhythmic activity at different frequencies in the desynchronized state

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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