Cell Biology

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Lung cells generated from mouse embryonic fibroblasts in just 7 to 10 days

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology.

3 Jul 2025

Cornell scientists use natural cell proteins to track molecular behavior

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living cells - using the cells' own components as built-in sensors.

2 Jul 2025

New strategy enhances immunotherapy effectiveness against glioblastoma by utilizing gut microbes

Advanced treatments, known as immunotherapies that activate T cells—our body's immune cells—to eliminate cancer cells, have shown limited efficacy as standalone therapies for glioblastoma, the most lethal form of brain tumor.

2 Jul 2025

Fidelio Capital partners with Alphalyse to accelerate the global roll-out of LC-MS host cell protein analytics

Alphalyse, a fast-growing Danish specialist contract research organization (CRO) that has developed GMP‑validated liquid‑chromatography mass‑spectrometry (LC‑MS) assays for host‑cell‑protein (HCP) impurity testing in biologic drugs, today announces that Fidelio Capital has acquired a majority stake in the company.

From Alphalyse A/S 2 Jul 2025

Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to develop new therapies for age driven diseases, today announced the results of a new study detailing an improved approach to ranking virtual cell models for gene discovery.

1 Jul 2025

Improving RNA drug delivery through intracellular traffic control

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of RNA-based drugs can significantly enhance their effectiveness.

1 Jul 2025

Study uncovers how inflammation in brain blood vessels exacerbates damage in vascular dementia

A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional recovery in mice.

1 Jul 2025

Expanding the genetic code in mammalian cells using pseudouridine modified codons

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of Chemistry and Molecular Engineering and Yi Chengqi from School of Life Sciences have developed a novel codon expansion strategy that enables precise incorporation of noncanonical amino acids (ncAAs) without perturbing natural genetic codes.

27 Jun 2025

Proteome imbalance from aneuploidy linked to mitochondrial dysfunction

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances.

27 Jun 2025

Protein cleavage mechanism sheds light on severe childhood ciliopathies

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, Joubert syndrome and other ciliopathies is cut in half to perform two separate functions, both of which are fundamental to the healthy development of children.

27 Jun 2025

New study reveals how diverse brain cells unite to guide decisions

Every decision begins invisibly. Long before someone acts, the brain is already hard at work gathering evidence, weighing options, and gradually committing to a choice.

27 Jun 2025

LMU researchers uncover mechanism for metabolism without cell membranes

LMU researchers have demonstrated a possible mechanism for metabolic processes without cell membranes in water-filled pores.

27 Jun 2025

New center in Copenhagen to pioneer the future of protein design

Proteins are the workhorses of biology. They perform virtually every important function in living organisms. They store, copy and protect our DNA, digest food to give us energy, and harness this energy to make our cells and muscles work.

27 Jun 2025

Yeast cell division found to begin inside the nucleus

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought.

26 Jun 2025

Unknown organelle discovery could open the door to new treatments for inherited diseases

The discovery of an unknown organelle inside our cells could open the door to new treatments for devastating inherited diseases.

26 Jun 2025

LINE-1 elements found essential for early embryonic development

A new review from Genes and Diseases sheds light on the pivotal role of LINE-1 elements in preimplantation development and totipotency, revealing their essential contributions to early mammalian embryogenesis.

25 Jun 2025

Scientists create ALS on a chip to uncover disease clues

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

24 Jun 2025

New technology unlocks cellular ancestry with DNA barcodes

A landmark study by WEHI scientists has shed new light on one of the most fundamental mysteries of biology: how cells divide and grow into the complex structures that make up our bodies.

24 Jun 2025

Using machine learning to map brain aging at the cellular level

In a comprehensive Genomic Press interview, Stanford University researcher Eric Sun reveals how machine learning is revolutionizing our understanding of brain aging at an unprecedented cellular resolution.

24 Jun 2025

Newly evolved genes reveal surprising role in human cell division

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria.

23 Jun 2025