Cell Biology

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Mitochondrial activity keeps dendritic cells ready to fight disease

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" state, linking cellular metabolism to gene regulation and T-cell activation.

15 Apr 2026

New model advances study of cardiac fibroblasts and fibrosis

Fibroblasts are an essential component of the heart, as they play key roles in its structure, development and response to cardiac damage.

15 Apr 2026

New research reveals how parasites break out of host cells

Parasites are a major global health problem, underlying many human diseases worldwide. For example, Plasmodium falciparum, the parasite responsible for malaria, plays a well-established; however, its complex life cycle is not yet fully understood.

15 Apr 2026

ORGAPRED selects CYTOQUBE® from Hamamatsu Photonics for personalized oncology research and therapeutic discovery

ORGAPRED, a France-based core facility specializing in Patient-Derived Tumor Organoid (PDTO) research, has selected the CYTOQUBE high-throughput 3D imaging system from Hamamatsu Photonics France to support personalized oncology drug screening and therapeutic discovery.

From Hamamatsu Photonics Europe 15 Apr 2026

VALANX Biotech establishes Scientific Advisory Board to advance ADC therapeutics

VALANX Biotech (VALANX), a biotech company developing novel technology for site-specific protein conjugation in drug discovery, today announced the formation of its Scientific Advisory Board (SAB), appointing John Lambert as Chair, with Morris Rosenberg and Peter de Waele serving alongside.

From VALANX Biotech 15 Apr 2026

Bayer receives MHRA approval for Kerendia® (finerenone) in adults with heart failure with LVEF ≥ 40 %

The Medicines and Healthcare products Regulatory Agency (MHRA) has granted approval for Kerendia® (finerenone), a non-steroidal, selective mineralocorticoid receptor antagonist (nsMRA), for the treatment of symptomatic chronic heart failure (HF) with left ventricular ejection fraction (LVEF) ≥ 40 %, in adults in the UK.

From Bayer PLC 13 Apr 2026

Pseudogene lncRNAs regulate cancer stem cell behavior and signaling

Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, and resistance to therapy due to their innate capacity for self-renewal and differentiation.

11 Apr 2026

Lung tumors shift identity making treatment more difficult

A new study co-led by the Institute for Systems Biology (ISB) shows that some lung cancers can change identity as they evolve, shifting from one cancer type to another in ways that may make them more aggressive and harder to treat.

10 Apr 2026

Researchers discover how motor proteins selectively transport neuronal cargo

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations.

10 Apr 2026

Revvity unveils its Signals BioDesign offering to advance biologic research workflows

Revvity, Inc. announced that its Revvity Signals Software business is launching Signals BioDesign™, a cloud-native molecular cloning solution that streamlines biologics research workflows.

From Revvity Signals Software Inc. 10 Apr 2026

New CellCelector CLD takes you from thousands of candidates to the top clone, faster

Sartorius announces the launch of the CellCelector CLD, an automated imaging and cell isolation platform designed to simplify and accelerate monoclonal cell line development (CLD).

From Sartorius 10 Apr 2026

Low oxygen triggers regenerative programs in mammalian limb cells

Some animals can regrow lost body parts. Salamanders and frog tadpoles can rebuild entire limbs after amputation. Mammals cannot. For decades, biologists have tried to understand why.

9 Apr 2026

Study maps DNA methylation changes driving MDS stem cell dysfunction

Published on April 01, 2026, in Volume 2, article number 19 of the journal Immunity & Inflammation, a collaborative team led by Prof. Cao at the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, along with Dr. Liangding Hu at the Fifth Medical Center of Chinese PLA General Hospital, and Professors Qian Zhang and Yanmei Han at the National Key Laboratory of Immunity and Inflammation, Naval Medical University, has generated the first base-resolution DNA methylome of human MDS HSCs.

9 Apr 2026

The FDA has released draft guidance for NAMs Validation – Now what?

On March 18th, the FDA published draft guidance on validating new approach methodologies (NAMs), including complex in vitro models (CIVMs).

From Hanson Wade Group - 11th 3D Tissue Models Summit 2026 9 Apr 2026

Virica Biotech and FUJIFILM Biosciences collaborate under the Canada-Japan Co-Innovation Program to advance AAV production enhancers

Virica Biotech ("Virica"), a cell enhancer company specializing in Viral Sensitizers (VSE™) for viral vector manufacturing, today announced it is receiving advisory services and funding from the National Research Council of Canada Industrial Research Assistance Program (NRC IRAP), under the Canada-Japan Corporate Co-Innovation Program for a collaboration with FUJIFILM Biosciences.

From Virica Biotech 9 Apr 2026

Stem cell study identifies universal checkpoint controlling cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages.

8 Apr 2026

New cell atlas reveals biological links to pregnancy complications

The biological connection between a pregnant woman and her developing baby has been mapped in unprecedented detail by UC San Francisco scientists, revealing new cell types and insights into conditions such as preeclampsia, preterm birth, and miscarriage.

8 Apr 2026

Study reveals how hyperdiploidy creates rare pre-leukemic clones in children

B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood cells, one of the most common abnormalities is the presence of cells with an excess of chromosomes (hyperdiploidy), a condition that leads to chromosomal instability.

8 Apr 2026

CIPHER-seq technology reveals how immune cells communicate during treatment

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

8 Apr 2026

RNA barcoding maps neural connections with unprecedented resolution

By tagging neurons with molecular "barcodes," researchers mapped connections among thousands of neurons in the mouse brain with unprecedented speed and resolution.

7 Apr 2026