Cell Biology

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Scientists create single-cell atlas of spinal neurons involved in motor coordination

Scientists at St. Jude Children's Research Hospital created a single-cell atlas of a key class of spinal neurons involved in motor coordination. From that resource, they identified a small subgroup of interneurons associated with the speed of rhythmic movements such as walking.

10 Aug 2026

New protein blueprint opens door for targeted Parkinson's disease therapies

Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state.

10 Aug 2026

New gene signature predicts immunotherapy success for bone marrow cancers

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow in cases of multiple myeloma and acute myeloid leukemia: A specific group of tumor-reactive T cells can recognize and, in principle, fight cancer cells, but is often not sufficiently activated.

10 Aug 2026

New pathway explains how zombie cells trigger chronic inflammation

Researchers have uncovered a previously unknown mechanism that helps aging cells drive the chronic inflammation linked to many age-related diseases.

10 Aug 2026

PRDM16 regulates the balance between proliferation and maturation in human cardiomyocytes

Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in cardiovascular biology.

7 Aug 2026

Researchers find a new genetic vulnerability in acute myeloid leukemia

A study published in Nature Cell Biology reports a new vulnerability in acute myeloid leukemia (AML) that might lead to novel therapies to treat this cancer while minimizing harm to normal cells.

7 Aug 2026

Fruit fly gut cells track hunger using internal cell viscosity

Researchers led by Sa Kan Yoo at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan have discovered that the natural turnover of gut cells in the fruit fly depends on how much food the flies get, rather than any specific nutrient.

7 Aug 2026

Exhausted T cells balance graft tolerance and infection risk

A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this dysfunctional immune state can both promote graft tolerance and create vulnerabilities to infection and malignancy.

7 Aug 2026

Phages explode bacteria to share vital vitamin B12 with microbes

Vitamin B12 is biological gold. All living organisms need a little bit of it to form red blood cells and DNA, as well as to build and support brain and nerve cells.

7 Aug 2026

Study uncovers how brain cells coordinate movement planning

Which neurons in the brain control movements, and how? This question was addressed by a team of researchers from the fields of neuroscience and artificial intelligence in a study conducted on an animal model at the interdisciplinary research centre BrainLinks-BrainTools at the University of Freiburg.

6 Aug 2026

LMU researchers reveal how different organs customize their internal clocks

LMU researchers have elucidated how different organs adapt the same clock machinery to regulate their individual needs over the course of a day.

6 Aug 2026

Localized biochemical halo of IL-10 suppresses immune rejection of pancreatic beta cells

A protein known as interleukin 10 (IL-10) is the lynchpin of a new method to protect transplanted cells from host immune system aggression.

6 Aug 2026

Hidden microbes inside tumors reshape cancer immunity and treatment

A growing body of evidence is reshaping how cancer is understood, placing the spotlight on intra-tumoral microbiota as powerful yet previously overlooked players within the tumor microenvironment.

6 Aug 2026

Neural stem cells split early into distinct neuron lineages

The cerebral cortex is densely packed with different nerve cells that enable us to perceive, think and act. Yet how these cell types arise while the brain develops is still not fully understood.

5 Aug 2026

Engineered spinal interneurons show promise for repairing spinal cord injuries

Spinal cord injuries affect an estimated 15 to 20 million people worldwide, often causing lasting impairments in movement, sensation, and independence.

5 Aug 2026

Cellular senescence drives progression of spinal disc degeneration and pain

A growing body of scientific insight is drawing attention to cellular senescence as a central force in the progression of intervertebral disc degeneration (IDD), a leading contributor to chronic low back pain worldwide.

5 Aug 2026

Review highlights the importance of miR-23b in shaping cancer development and progression

A new review highlights the growing importance of miR-23b, a small but powerful regulator of gene expression, in shaping the development and progression of a wide range of cancers.

5 Aug 2026

Versatile receptor protein plays critical role in regulating tissue repair

A comprehensive new review highlights the expanding importance of Lgr6, a member of the G protein-coupled receptor family, as a critical regulator of tissue homeostasis, injury repair, and disease development across multiple organ systems.

5 Aug 2026

Specialized selenoproteins play critical role in regulating cellular health

A new review highlights the remarkable importance of selenoproteins, a specialized group of molecules that, despite their small size, play a decisive role in shaping cellular fate and maintaining biological balance.

5 Aug 2026