Cell Biology

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Scientists map genetic changes controlling the immune sensor STING

The immune system depends on molecular alarms that detect danger inside cells. One of these alarms is STING, short for "stimulator of interferon genes".

24 Jun 2026

Microbes trigger cell death to boost cancer immunotherapy effectiveness

Traditional cancer treatments like chemotherapy and radiotherapy can induce immunogenic cell death (ICD), but their efficacy is often limited by drug resistance, severe off-target toxicity, and immune-related adverse events.

24 Jun 2026

Pioneering technique maps the proteome of individual cardiomyocytes

Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes-the cells responsible for heart contraction.

24 Jun 2026

Hidden protein linked to severe COVID-19 and lung disease risk

A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study.

24 Jun 2026

Cytoskeletal proteins in the cell nucleus influence brain development

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and the Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are also found in the cell nucleus, where they can influence developmental programs.

23 Jun 2026

New project aims to systematically map billion cellular interactions

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23 Jun 2026

Optimized proximity labeling platform tracks cellular protein communication networks

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these messages to organs throughout the body.

22 Jun 2026

New method generates renewable supply of progenitor immune cells

In a paper published in Cell, a USC Stem Cell-led team reports a new way of generating a renewable and expandable supply of the progenitor cells that give rise to macrophages.

19 Jun 2026

New optical technique uses light to reveal internal contents of chicken eggs

Scientists have demonstrated a non-invasive technique that uses light to reveal the hidden contents of chicken eggs, potentially helping to curb the meat industry's practice of killing billions of male chicks at birth.

19 Jun 2026

Gene deletion exposes hidden colon cancer cells to immunotherapy attack

A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy - a fundamental breakthrough.

18 Jun 2026

Early life stress leaves unique biological signatures in cells

New research links childhood adversity to mitochondrial bioenergetic changes later in life, underscoring the impact of stress in early life on cellular health.

18 Jun 2026

Key Alzheimer's protein actively protects neurons from nuclear damage

Researchers at Niigata University's Brain Research Institute have uncovered a new function of amyloid precursor protein (APP), a molecule long studied as the precursor to amyloid-β (Aβ) in Alzheimer's disease (AD).

17 Jun 2026

Developing brain cells routinely repair severe DNA damage during migration

Newborn nerve cells must squeeze through crowded, narrow spaces-through dense tissue, past other cells, between fibers-to reach the areas where they form neural circuits in the brain cortex.

17 Jun 2026

New pico-calorimeter detects antibiotic resistance via direct heat traces

When living cells grow, divide, or respond to drugs, they give off tiny amounts of heat that offer information about what the cells are doing. But since these heat signals are so vanishingly small, they have been traditionally impossible to measure directly.

17 Jun 2026

Researchers eliminate embryonic senescent cells, triggering severe neurovascular flaws

Among the body's most crucial protective features are the brain barrier systems, including the blood-brain and blood-cerebrospinal fluid (CSF) barriers. These barriers are made of highly specialized cells that allow essential nutrients to enter, yet repel dangerous toxins and pathogens that may be circulating in the bloodstream. Scientists have long known what these barriers do, but less about how they are built during development.

17 Jun 2026

Dual-target CAR T therapy triggers broad immune response in brain cancer

Dual-target CAR T cell therapy for recurrent glioblastoma (GBM), delivered directly into the cerebrospinal fluid (CSF), triggers a broad immune response, with natural killer (NK) cell activation linked to better patient outcomes and longer overall survival.

15 Jun 2026

Gut cell study discovers lasting molecular scars of Crohn's disease

A detailed cellular study of Crohn’s disease has mapped how gene activity changes across more than 50 cell types in the gut.

15 Jun 2026

Cellular process discovery may lead to new cancer treatments

A molecular geneticist at Montana State University has discovered a cellular process once believed impossible by scientists – the creation of the amino acid cysteine within a living cell when the cell's primary systems to do so fail. The discovery may one day lead to new cancer treatments.

12 Jun 2026

Ancient unicellular organism offers clues to animal origins

A recent study by Ruibao Li and Jennah Dharamshi published in Nature may help us understand the beginnings of animal evolution billions of years ago.

12 Jun 2026

Laser phase plate dramatically expands cryo-EM imaging capabilities

In a landmark achievement in biological imaging, researchers at the University of California, Berkeley and Biohub today announced the successful demonstration of the laser phase plate, a novel device that dramatically improves the contrast of images produced by cryo-electron microscopes, opening up an entirely new view of human biology.

11 Jun 2026