Cell Biology

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Low oxygen triggers regenerative programs in mammalian limb cells

Some animals can regrow lost body parts. Salamanders and frog tadpoles can rebuild entire limbs after amputation. Mammals cannot. For decades, biologists have tried to understand why.

9 Apr 2026

Study maps DNA methylation changes driving MDS stem cell dysfunction

Published on April 01, 2026, in Volume 2, article number 19 of the journal Immunity & Inflammation, a collaborative team led by Prof. Cao at the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, along with Dr. Liangding Hu at the Fifth Medical Center of Chinese PLA General Hospital, and Professors Qian Zhang and Yanmei Han at the National Key Laboratory of Immunity and Inflammation, Naval Medical University, has generated the first base-resolution DNA methylome of human MDS HSCs.

9 Apr 2026

The FDA has released draft guidance for NAMs Validation – Now what?

On March 18th, the FDA published draft guidance on validating new approach methodologies (NAMs), including complex in vitro models (CIVMs).

From Hanson Wade Group - 11th 3D Tissue Models Summit 2026 9 Apr 2026

Virica Biotech and FUJIFILM Biosciences collaborate under the Canada-Japan Co-Innovation Program to advance AAV production enhancers

Virica Biotech ("Virica"), a cell enhancer company specializing in Viral Sensitizers (VSE™) for viral vector manufacturing, today announced it is receiving advisory services and funding from the National Research Council of Canada Industrial Research Assistance Program (NRC IRAP), under the Canada-Japan Corporate Co-Innovation Program for a collaboration with FUJIFILM Biosciences.

From Virica Biotech 9 Apr 2026

Stem cell study identifies universal checkpoint controlling cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages.

8 Apr 2026

New cell atlas reveals biological links to pregnancy complications

The biological connection between a pregnant woman and her developing baby has been mapped in unprecedented detail by UC San Francisco scientists, revealing new cell types and insights into conditions such as preeclampsia, preterm birth, and miscarriage.

8 Apr 2026

Study reveals how hyperdiploidy creates rare pre-leukemic clones in children

B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood cells, one of the most common abnormalities is the presence of cells with an excess of chromosomes (hyperdiploidy), a condition that leads to chromosomal instability.

8 Apr 2026

CIPHER-seq technology reveals how immune cells communicate during treatment

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

8 Apr 2026

RNA barcoding maps neural connections with unprecedented resolution

By tagging neurons with molecular "barcodes," researchers mapped connections among thousands of neurons in the mouse brain with unprecedented speed and resolution.

7 Apr 2026

Study reveals how Bcl-2 protein blocks cancer cell death

Researchers at Umeå University have contributed new insights into how cancer cells protect themselves from cell death.

7 Apr 2026

CiQUS researchers develop flexible chemical strategy to create biomimetic synthetic cells

A team at the Center for Research in Biological Chemistry and Molecular Materials (CiQUS) at the University of Santiago de Compostela has developed a more flexible chemical strategy to create biomimetic structures—artificial systems that mimic cellular functions.

7 Apr 2026

New strategy exploits specific genetic vulnerability in colorectal cancer patients

Researchers have identified a novel therapeutic approach for colorectal cancer by exploiting a specific genetic vulnerability found in a majority of patients.

6 Apr 2026

Deep UV microscopy enables label-free T cell characterization

A team of researchers at the Georgia Institute of Technology and Emory University has developed a deep-ultraviolet (UV) microscopy method that can rapidly assess T cell viability, activation state, and subtype-all without the need for fluorescent labels or cell destruction.

3 Apr 2026

Nanotube membrane injector enables precise transfer of cytoplasmic contents between cells

Cells are not isolated units; they continuously exchange proteins, genetic material, and even entire organelles with their neighbors.

3 Apr 2026

International researchers set new standards for studying tumor microbiota

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

2 Apr 2026

PRISM ALS: A new global collaboration to expand patient-derived stem cell models and accelerate treatments

A new global initiative launched today aims to close a critical gap in ALS/MND drug discovery - current cell models used for testing treatments do not currently reflect the diverse nature of the disease - that affects both researchers developing therapies and the people urgently waiting for them.

From ALS Therapy Development Institute (ALS TDI) 1 Apr 2026

Study reveals molecular control of tooth root formation and growth

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to control signaling and differentiation in dental progenitor cells.

1 Apr 2026