Cell Biology

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CRISPR-based Cellgorithm technology ushers in a new era of cell programming

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company's CRISPR-based Cellgorithm technology, which lays the groundwork for programmable control of gene activity in human stem cells and offers an alternative to the slow, variable manual processes researchers use today.

5 Dec 2025

Tenascin C as a key to restoring muscle regeneration in aging

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky.

5 Dec 2025

Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis

Leber Congenital Amaurosis (LCA) is an inherited retinal disease leading to severe vision impairment from early infancy, affecting 2-3 out of every 100,000 newborns. LCA is caused by variants in certain genes from which proteins essential for retinal cell function and survival are made.

3 Dec 2025

NeuMap unveils the hidden architecture and life-long patterns of human neutrophils

Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage.

3 Dec 2025

New method reveals how human cells initiate DNA replication

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, and genetic disorders. Therefore, understanding how cells replicate their DNA is crucial for elucidating fundamental biological processes, diseases, and even evolution.

3 Dec 2025

Stem cells reshape in response to electrical signals, study reveals

Scientists in Melbourne have discovered how tiny electrical pulses can steer stem cells as they grow, opening the door to new improved ways of creating new tissues, organs, nerves and bones.

3 Dec 2025

New study reveals how brain biology shapes thought and behavior

A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain's smallest components build the systems that shape thought, emotion and behavior.

2 Dec 2025

Cell nucleus shape plays a key role in cancer therapy outcomes

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden.

2 Dec 2025

Atelerix and Labskin partner to enable long-distance transport of advanced in vitro skin models

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced an agreement with Labskin, a global leader in laboratory-grown human skin models used for research, testing and product development.

2 Dec 2025

New technique helps understand how bacterial shapes contribute to disease

Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean has remained a major challenge, especially for species that can't be grown in the lab. Now, a new study led by Nina Wale, an Assistant Professor in MSU's Department of Microbiology, Genetics, & Immunology, introduces a groundbreaking method that could change how researchers study bacterial diversity.

1 Dec 2025

Neural stem cells drive lifelong eye growth in marine bristleworms

A new study, led by the University of Vienna and the Alfred Wegener Institute in Bremerhaven, shows how the eyes of adult marine bristleworms continue to grow throughout life – driven by a ring of neural stem cells reminiscent of vertebrate eyes.

1 Dec 2025

Innate immunity and metabolic stress drive a unique form of cell death

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together.

1 Dec 2025

Study reveals ATM kinase as the key driver of replicative senescence

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective caps at the chromosome ends-those caps eventually become too short to prevent chromosome ends from being recognized as DNA breaks.

1 Dec 2025

Machine learning tool identifies compounds that induce cancer cells into senescence

A new research paper featured on the cover of Volume 17, Issue 11 of Aging-US was published on October 30, 2025, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

1 Dec 2025