Cell Biology

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Novel assay helps identify factors that can convert normal cells into liver cancer cells

Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients.

7 Sep 2021

Research project focusing on membraneless organelles receives funding from Volkswagen Foundation

As part of its "Life?" project, the Volkswagen Foundation is funding a research project that is placing membraneless organelles within cells in the spotlight as a way of understanding the fundamental processes that are essential to life.

6 Sep 2021

Researchers uncover underlying metabolic changes that are linked to COVID-19 severity

COVID-19 patients have differing immune responses that lead to disease outcomes ranging from asymptomatic SARS-CoV-2 infection to death.

6 Sep 2021

Cancer treatment with terpyridine platinum compounds induces telomere dysfunction, chromosome instability

Oncotarget published "Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells" which reported that this assay is based on the use of two isogenic HT1080 cell lines, one carrying a linear HAC and the other carrying a circular HAC.

6 Sep 2021

Neuroscientists visualize ultrastructural changes to dendritic spines during structural plasticity

Researchers at the Max Planck Florida Institute for Neuroscience have developed a new imaging technique capable of visualizing the dynamically changing structure of dendritic spines with unprecedented resolution.

6 Sep 2021

Researchers develop the smallest CRISPR to date for genome editing

A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells. The findings appear in a study publishing September 3 in the journal Molecular Cell.

4 Sep 2021

Scientists identify a critical checkpoint in transcription elongation

Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.

4 Sep 2021

Study uncovers new mechanism for memory transfer between individual roundworms

When an organism encounters a threat in its environment, it is to the species' advantage to warn others of the peril.

4 Sep 2021

Temperature variations could have driven the division of protocells

A simple mechanism could underlie the growth and self-replication of protocells-;putative ancestors of modern living cells-;suggests a study publishing September 3 in Biophysical Journal.

4 Sep 2021

Gut microbiome patterns provide clues to brain damage in extremely premature infants

Extremely premature infants are at a high risk for brain damage. Researchers at the University of Vienna and the Medical University of Vienna have now found possible targets for the early treatment of such damage outside the brain: Bacteria in the gut of premature infants may play a key role.

4 Sep 2021

Stem-like T cells within certain lymph nodes could be natural cancer fighters, study shows

In a new study by Yale Cancer Center, researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters.

3 Sep 2021

CAR T cells expressing a natural RNA can activate the body’s own T cells against solid tumors

Chimeric antigen receptor (CAR) T cell therapy, which uses engineered T cells to treat certain types of cancers, has often been a challenging approach to treating solid tumors. CAR T cells need to recognize a specific target on cancer cells to kill them.

2 Sep 2021

New computational approach may predict how individuals are likely to respond to vaccines

In an advance that sheds light on why certain vaccines may influence people differently, a new computational approach developed at the University of Michigan may predict how individual patients are likely to respond.

2 Sep 2021

Cryogenic storage of biological specimens

Ziath, a leading supplier of equipment, software and consumables to simplify your sample management process, offers a range of CryzoTraq™ tubes designed for high integrity cryogenic storage of biological specimens at temperatures down to -196°C.

From Ziath Ltd 2 Sep 2021

Study identifies how immune sensors launch a multi-faceted innate immune response to infections

St. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and launch a multi-faceted innate immune response to infections with live viruses and bacteria. The discovery appears today in Nature.

2 Sep 2021

Immune cells present in tumors from head and neck cancer patients, study reports

A new study from scientists at Emory Vaccine Center and Winship Cancer Institute of Emory University reports that the immune cells that are the major targets of immune checkpoint inhibitors are present in tumors from head and neck cancer patients.

2 Sep 2021

Uppsala researchers find solution to long-standing biological search enigma

How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university have now discovered the solution; it is easier to find a rope than a ball if you are blindfolded.

1 Sep 2021

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Human evolution has provided us a level of protection from the existential threat of cold temperature with the capacity to produce heat from fat stored in the body.

1 Sep 2021

New low-cost technique helps profile dynamic metabolic features from single isogenic cells

Researchers with the Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, have developed a fast, low-cost and high-throughput technique capable of profiling dynamic metabolic features from just one isogenic sample of cells.

1 Sep 2021

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of lung disease characterized by relentless scarring leading to death within an average of four years from the time of diagnosis.

31 Aug 2021

Cell Biology

Novel assay helps identify factors that can convert normal cells into liver cancer cells

Research project focusing on membraneless organelles receives funding from Volkswagen Foundation

Researchers uncover underlying metabolic changes that are linked to COVID-19 severity

Cancer treatment with terpyridine platinum compounds induces telomere dysfunction, chromosome instability

Neuroscientists visualize ultrastructural changes to dendritic spines during structural plasticity

Researchers develop the smallest CRISPR to date for genome editing

Scientists identify a critical checkpoint in transcription elongation

Study uncovers new mechanism for memory transfer between individual roundworms

Temperature variations could have driven the division of protocells

Gut microbiome patterns provide clues to brain damage in extremely premature infants

Stem-like T cells within certain lymph nodes could be natural cancer fighters, study shows

CAR T cells expressing a natural RNA can activate the body’s own T cells against solid tumors

New computational approach may predict how individuals are likely to respond to vaccines

Cryogenic storage of biological specimens

Study identifies how immune sensors launch a multi-faceted innate immune response to infections

Immune cells present in tumors from head and neck cancer patients, study reports

Uppsala researchers find solution to long-standing biological search enigma

Immune cell betrayal makes aging mice less tolerant of cold temperatures

New low-cost technique helps profile dynamic metabolic features from single isogenic cells

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Next-Gen Sequencing And The Diagnosis of Disease

In-depth sequencing of SARS-CoV-2 variants crucial in controlling outbreaks

Increasing your risk of IBD through processed food

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