Cell Biology

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Stress protein in fibroblasts appears to be an attractive cancer drug target

A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future cancer treatments, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

10 Jun 2022

Naturally-produced antibodies in mothers may enhance infants' immunity against bacterial pathogens

Researchers have known for some time that maternal breast milk provides critical nutrients for newborns, and antibodies from mothers vaccinated against a specific disease-causing bacterium or virus can be transferred via breast milk to babies.

10 Jun 2022

Deciphering the structure of nuclear pore complex piece by piece

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work.

10 Jun 2022

Creating CAR T cells without an immune brake

T cells are usually very good at eliminating diseased cells. But they seem to fail when it comes to tumor cells.

10 Jun 2022

Brain area communication changes over much faster timescales than previously thought

Understanding how brain areas communicate is one of the oldest questions in neuroscience. Researchers at the Sainsbury Wellcome Centre at UCL used causal techniques to uncover how two neocortical areas in the brain communicate with one another and found that their influence on each other changes over much faster-timescales than previously thought.

10 Jun 2022

New, tiny probe for long-lasting and minimally invasive interfacing with neural circuits

Researchers at the University of California San Diego and the Salk Institute for Biological Studies have developed a tiny neural probe that can be implanted for longer time periods to record and stimulate neural activity, while minimizing injury to the surrounding tissue.

9 Jun 2022

Genomic analysis provides a deeper understanding of DCIS biology

A new study led by the global Cancer Grand Challenges PRECISION team, including researchers from The University of Texas MD Anderson Cancer Center, shifts the long-held belief that all invasive breast cancers following ductal carcinoma in situ (DCIS) arise from the original DCIS lesion.

9 Jun 2022

Aspirin changes the way colorectal cancer cells evolve over time, study reveals

Cancer starts when cells start dividing uncontrollably. Scientists have known that taking aspirin can help protect against the development of colorectal cancer – cancer afflicting the colon or rectum – but the exact reason aspirin has this effect has been mostly a mystery.

9 Jun 2022

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

9 Jun 2022

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.

9 Jun 2022

Researchers reveal important factor behind cancer therapy resistance and a way to counter it

Why doesn't every cancer patient respond to immunotherapy? That's the question that researcher Daniel Peeper is looking to answer.

9 Jun 2022

Research reveals how highly proliferative leukemia cells turn into normal harmless ones

A new research describes how highly proliferative leukemia cells end up becoming normal cells that no longer multiply, by changing the chemical modifications -the so-called epigenetics- of a type of its genetic material: the messenger RNA.

9 Jun 2022

Researchers create first comprehensive functional map of genes expressed in human cells

The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including Whitehead Institute, and was finally completed in 2003.

9 Jun 2022

Study sheds new light on the role of transcription factors in bone marrow microenvironments

In your home, storing books on a bookshelf, tools in a tool box, and a broom in a broom cupboard makes it easy to access these items whenever you need them.

9 Jun 2022

Olympus Provi™ CM20 wins highest honor in world-renowned design competition

Evident, a wholly owned subsidiary of Olympus Corporation, is proud to announce that its Olympus Provi™ CM20 incubation monitoring system is the 2022 recipient of the prestigious "Best of the Best" award in the Product Design category of the Red Dot Design Award. This Award is bestowed on a product that the Red Dot Jury deems as groundbreaking and is the highest honor given in this world-renowned design competition.

From Evident Corporation 9 Jun 2022

Stem cell models help determine previously unknown genetic markers of glaucoma

Stem cell models of the retina and optical nerve have been used to identify previously unknown genetic markers of glaucoma, in research jointly led by scientists from the Garvan Institute of Medical Research, the University of Melbourne, and the Centre for Eye Research Australia.

9 Jun 2022

Most synonymous genetic mutations are strongly harmful, study shows

In the early 1960s, University of Michigan alumnus Marshall Nirenberg and a few other scientists deciphered the genetic code of life, determining the rules by which information in DNA molecules is translated into proteins, the working parts of living cells.

8 Jun 2022

Synthetic IL-9 receptor allows T cells to fight cancer without the need for chemo or radiation

Before a patient can undergo T cell therapy designed to target cancerous tumors, the patient's entire immune system must be destroyed with chemotherapy or radiation. The toxic side effects are well known, including nausea, extreme fatigue and hair loss.

8 Jun 2022

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Using advanced microscopy techniques, researchers at Karolinska Institutet and Stockholm University in Sweden have visualized in unprecedented detail the machinery that the cells' powerhouses, the mitochondria, use to form their proteins.

8 Jun 2022

Detailed genetic roadmap of glaucoma will help develop new drugs to combat the disease

A new, detailed genetic roadmap of glaucoma – the world's leading cause of irreversible blindness – will help researchers develop new drugs to combat the disease, by identifying potential target areas to stall or reverse vision loss.

8 Jun 2022

Cell Biology

Stress protein in fibroblasts appears to be an attractive cancer drug target

Naturally-produced antibodies in mothers may enhance infants' immunity against bacterial pathogens

Deciphering the structure of nuclear pore complex piece by piece

Creating CAR T cells without an immune brake

Brain area communication changes over much faster timescales than previously thought

New, tiny probe for long-lasting and minimally invasive interfacing with neural circuits

Genomic analysis provides a deeper understanding of DCIS biology

Aspirin changes the way colorectal cancer cells evolve over time, study reveals

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers reveal important factor behind cancer therapy resistance and a way to counter it

Research reveals how highly proliferative leukemia cells turn into normal harmless ones

Researchers create first comprehensive functional map of genes expressed in human cells

Study sheds new light on the role of transcription factors in bone marrow microenvironments

Olympus Provi™ CM20 wins highest honor in world-renowned design competition

Stem cell models help determine previously unknown genetic markers of glaucoma

Most synonymous genetic mutations are strongly harmful, study shows

Synthetic IL-9 receptor allows T cells to fight cancer without the need for chemo or radiation

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

Detailed genetic roadmap of glaucoma will help develop new drugs to combat the disease

Combining AI and Zebrafish to Accelerate Drug Discovery

Connecting Health and Social Care to Improve Community Health

Just like magic; automated solutions for NGS library preparation

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