Cell Biology

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Scientists identify key role of T-bet in flu memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out.

11 Jul 2025

New discovery uncovers hidden drivers of DNA transcription errors

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

11 Jul 2025

Researchers create over 400 types of nerve cells from stem cells

Nerve cells are not just nerve cells. Depending on how finely we distinguish, there are several hundred to several thousand different types of nerve cell in the human brain according to the latest calculations.

11 Jul 2025

Mitochondria and peroxisomes work together to defend against cell damage

An international team led by researchers at The Hospital for Sick Children (SickKids), Princess Margaret Cancer Centre, Dalhousie University, the University of Exeter (UK) and the Medical University of Vienna (Austria) has uncovered a surprising way compartments within cells work together to defend themselves against oxidative stress, a finding that could shift how we understand age-associated conditions such as diabetes and neurodegenerative diseases.

10 Jul 2025

New type of algae offers breakthrough in cell cultivation

The time it takes to grow new skin for burns victims could be improved thanks to a new method of cell cultivation using algae, developed by University of Queensland researchers.

10 Jul 2025

Researchers uncover molecular switch controlling DNA packing in cell division

If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged.

10 Jul 2025

Sticky cell coating boosts liver repair without the need for transplants

A new process could help to treat liver disease without needing an organ transplant, a new study reveals.

10 Jul 2025

Chan Zuckerberg initiative unveils AI model to decode cellular behavior

Today, the Chan Zuckerberg Initiative (CZI) announced its latest AI model aimed at helping researchers better understand how cells behave by focusing on the key networks that control cell behavior, making complex biological problems, like cancer, easier to solve.

10 Jul 2025

Exercise improves cancer outcomes by shaping the gut microbiome

A new study from the University of Pittsburgh shows for the first time how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome.

9 Jul 2025

Energy waves on cancer cell surfaces linked to tumor growth and aggressiveness

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of power-generating waves on the covering, or membrane, of these cells.

9 Jul 2025

SPT Labtech and Semarion collaborate to advance automated cell-based assay workflows

SPT Labtech, a global leader in innovative laboratory automation, today announced a strategic collaboration with Semarion, a University of Cambridge spin-out company from the Cavendish Laboratory combining materials engineering and cell biology to tackle unmet drug screening needs.

9 Jul 2025

Stem cells transform into bone cells by squeezing through narrow spaces

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

8 Jul 2025

Scientists uncover hidden superfamily of lipid trapping proteins in bacteria

Scientists have identified a new type of protein in bacteria that could change our understanding of how these organisms interact with their environments.

8 Jul 2025

Smallest known protein-based enzyme HARP reveals dual role in tRNA processing

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the right amino acids to ribosomes, the cell's protein-making factories.

7 Jul 2025

New AI-informed method accelerates protein engineering

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences has developed a groundbreaking method that could transform the field of protein engineering.

7 Jul 2025

Innovative bispecific antibody targets LAG-3 to treat autoimmune diseases

Immune checkpoint pathways regulate T cell function and play pivotal roles in the treatment of both cancer and autoimmune diseases.

7 Jul 2025

Study provides a molecular snapshot of Tanshi constitution's immunological landscape

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional Chinese medicine (TCM)—using single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs).

7 Jul 2025

Mitochondria depletion in stem cells offers insights into cellular energy and evolution

By using a genetic technique developed at UT Southwestern Medical Center that forces cells to rid themselves of mitochondria, researchers are gaining new insights into the function of these critical organelles.

7 Jul 2025

Novel tool offers a glimpse into the black box of ALT in aggressive cancers

Each time a cell divides, a small section of each chromosome's protective cap - the telomere - is worn away. Most cells use an enzyme called telomerase to help mitigate this loss, but 10% to 15% of cancers have another mechanism called the alternative lengthening of telomeres (ALT) pathway.

4 Jul 2025

First large-scale stem cell bank created to investigate Alzheimer’s genetic risk factors

Alzheimer's disease (AD) is a common, debilitating neurodegenerative disease affecting about 10 percent of people over the age of 65 and one third of people aged 85 and above. Besides environmental factors, the genes have a strong influence on whether or not a person develops AD during their lifetime.

4 Jul 2025