Cell Biology

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New technology unlocks secrets of bacterial gene expression

How do bacteria - harmless ones living in our bodies, or those that cause disease - organize their activities? A new study, combining powerful genomic-scale microscopy with a technical innovation, captured which genes bacteria turn on in different situations and in different spatial environments.

6 Feb 2025

MaxCyte® acquires SeQure Dx to broaden cell engineering offerings with on-target and off-target editing assessments

MaxCyte, Inc., a leading, cell-engineering focused company providing solutions to advance the discovery, development and commercialization of next-generation cell therapeutics announced today the acquisition of SeQure Dx, a market leader of on-target and off-target editing assessment services for cell and gene therapies.

From MaxCyte, Inc. 6 Feb 2025

Study reveals how healthy stem cells transform into cancer cells

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

5 Feb 2025

New study reveals how anticancer drugs enter cancer cells

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell.

5 Feb 2025

Researchers discover how RNA molecules influence multiple generations

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies.

4 Feb 2025

Study reveals surprising resilience of chromatin to aging

The way the body ages could be more resilient than previously thought, a new study suggests.

4 Feb 2025

Engineered fat cells starve tumors and prevent cancer growth

Scientists transformed energy-storing white fat cells into calorie-burning 'beige' fat. Once implanted, they outcompeted tumors for resources, beating back five different types of cancer in lab experiments.

4 Feb 2025

New discovery offers hope for stopping childhood brain tumors before they start

Scientists at The Hospital for Sick Children (SickKids) have discovered a way to stop tumour growth before it starts for a subtype of medulloblastoma, the most common childhood malignant brain cancer.

4 Feb 2025

Blocking a protein could halt the growth of fast-growing cancers

Preventing the cell's protein factories from making the notorious cancer-causing protein MYC could stop out-of-control tumors.

4 Feb 2025

New microscopy technique uncovers 'ribosome cooperativity' in difficult situations

Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells.

31 Jan 2025

New findings could make off-the-shelf CAR T cell therapy a reality

CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets on the surface of the cancer cell.

31 Jan 2025

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

31 Jan 2025

Researchers create random versions of human genomes to study disease

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

31 Jan 2025

Breakthrough model simulates human bone marrow function in the lab

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells.

31 Jan 2025

New light-controlled tools offer real-time protein control in living cells

A research group at Umeå University has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells.

30 Jan 2025

New research shines light on position-specific hallmarks of cancer

A team led by the Cancer Immunogenomics group at the Josep Carreras Leukaemia Research Institute, the Computational Biology group at the Barcelona Supercomputing Center and the Germans Trias i Pujol Research Institute shows, for the first time, that within a tumor, the expression of the different hallmarks of cancer is not cell-specific, but rather position-specific.

30 Jan 2025

Bioengineers create non-invasive way to control cells using temperature

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

29 Jan 2025

High-speed in-line force mapping unveils E. coli cell division dynamics

Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller features, and electron microscopy resolves small structures, but samples must be meticulously prepared, killing any live specimens.

29 Jan 2025

New approach unveiled to accurately predict and engineer protein metalation

Researchers at Durham University have achieved a major advancement in understanding how proteins bind metals inside cells, a process crucial to life.

29 Jan 2025

Exploring the interaction between cell death and cellular senescence in cancer

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

29 Jan 2025