Cell Biology

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LUC7 proteins play crucial role in efficient RNA splicing

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut out and the coding portions are spliced back together.

21 Feb 2025

New 3D lung model advances respiratory medicine research

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct dosage.

20 Feb 2025

Exploring how 25-hydroxycholesterol triggers ferroptosis in glial cells

Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis.

20 Feb 2025

New approach shows promise for treating fragile X syndrome

Building on more than two decades of research, a study by MIT neuroscientists at The Picower Institute for Learning and Memory reports a new way to treat pathology and symptoms of fragile X syndrome, the most common genetically-caused autism spectrum disorder.

20 Feb 2025

Blood immune cells found to impact cancer survival

The immune systems of cancer patients are highly disrupted, with those who have a higher number of immune cells in their blood having a better survival rate, finds a new study that uses a pioneering technique developed by researchers at UCL and the Francis Crick Institute.

20 Feb 2025

Cancer cells cooperate to source nutrients and support tumor growth

Cancer cells work together to source nutrients from their environment-a cooperative process that was previously overlooked by scientists but may be a promising target for treating cancer.

19 Feb 2025

Study uncovers molecular mechanisms behind insulin resistance in skeletal muscle

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide.

19 Feb 2025

New mRNA technique targets disease cells while sparing healthy ones

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

19 Feb 2025

SwRI develops computational method to track brain cell development

A team led by Southwest Research Institute (SwRI) developed a computational method to improve techniques to track brain cell development over time.

18 Feb 2025

ChromTR revolutionizes chromosome detection in metaphase cell images

ChromTR, a cutting-edge framework for chromosome detection in metaphase cell images, represents a significant advancement in the field of cytogenetics.

17 Feb 2025

Study sheds new light on brain evolution

In a new study published in Science, a Belgian research team explores how genetic switches controlling gene activity define brain cell types across species.

17 Feb 2025

Study shows how pituitary macrophages impact hormone regulation

Finnish researchers show in a new study that pituitary macrophages, the immune cells located in the pituitary gland, help regulate hormonal balance. It is possible that in the future, macrophage cells could be used to treat endocrine disorders that can lead, for example, to infertility.

17 Feb 2025

Researchers develop a way to treat muscular atrophy using regenerative medicine

Researchers from Tokyo Metropolitan University have developed a way to treat ageing-related muscular atrophy using regenerative medicine.

17 Feb 2025

New discovery on mitochondrial protein could transform Charcot-Marie-Tooth treatment

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading cause in the currently incurable neurological disease Charcot-Marie-Tooth (CMT).

14 Feb 2025

Dead bacteria offer nutrients to neighbors through evolved enzyme

Darwin's theory of natural selection provides an explanation for why organisms develop traits that help them survive and reproduce.

14 Feb 2025

New insight into gut stem cell aging

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signaling is essential for preserving the intestinal stem cell population during aging.

13 Feb 2025

New atlas reveals aging’s impact on breast tissue and cancer risk

Aging is a privilege, but it also brings risks-including an increased likelihood of developing age-related diseases including cancer.

13 Feb 2025

Study reveals key mechanisms behind cancer cells adapting to extra chromosomes

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

13 Feb 2025

Breakthrough discovery reveals key role of ovoid cells in object recognition memory

Take a look around your home and you'll find yourself surrounded by familiar comforts-photos of family and friends on the wall, well-worn sneakers by the door, a shelf adorned with travel mementos.

13 Feb 2025

Protein shuttling mechanism enables bacteria to survive exposure to antibiotics

A Cornell University-led collaboration has uncovered the equipment that enables bacteria to survive exposure to antibiotics: a shuttling mechanism that helps a complex of proteins pump out a wide spectrum of antibiotics along with other physiological substrates from the cell.

13 Feb 2025