Cell Biology

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New 3D model reveals hidden role of stem cells in sense of smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

11 Jun 2025

Maternal iron deficiency disrupts embryonic sex determination in mice

Developmentally expressed genes play a fundamental role in the formation of a wide range of organs. The Y chromosome-located mammalian sex-determining gene Sry, required for the formation of testis, is activated only within a narrow time window during embryogenesis.

11 Jun 2025

ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress.

11 Jun 2025

Scientists discover hundreds of new metabolites linked to the human microbiome

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us.

10 Jun 2025

Inhibiting cancer cells' energy source with natural acid ester

Looking to nature for answers to complex questions can reveal new and unprecedented results that can even affect cells on molecular levels.

10 Jun 2025

CN Bio introduces cross-species DILI services to enhance in vitro to in vivo extrapolation during preclinical drug development

CN Bio, a leading provider of Organ-on-a-chip (OOC) systems and solutions that accelerate drug discovery and development workflows, has introduced two new animal microphysiological system (MPS) models that enhance translatability in preclinical drug safety and toxicology assessments to its Contract Research Services (CRS). Building upon the Company's FDA-recognized drug induced liver injury (DILI) assay, the expanded offering enables rapid, comparative studies between commonly used animal and human models to flag interspecies differences early, and better informs in vivo study design.

10 Jun 2025

Patient-derived xenograft models may become an indispensable tool in precision oncology

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision medicine and targeted therapies have transformed treatment strategies, many patients still face drug resistance and disease recurrence.

10 Jun 2025

New insights into the physical principles behind embryo development

During embryonic development, thousands of cells divide and move collectively to sculpt the main body axes.

9 Jun 2025

Study offers new insights into how the body clears dead cells during stress

A new study from The University of Texas at Arlington details a novel strategy for how the body clears out dead cells during stress, revealing unexpected roles for well-known stress-response genes-a discovery that could help scientists better understand diseases affecting the immune system, brain and metabolism.

9 Jun 2025

Shift Bioscience identifies novel single-gene target for safer cellular rejuvenation therapeutics

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to develop new therapies for age driven diseases, today announced the publication of new research identifying a novel, single-gene target for cellular rejuvenation.

9 Jun 2025

New study maps how cells allocate space to organelles during growth

Picture a living cell as if it were a city. If you were the urban planner for this (very little, very alive) city, one of the things you would have to decide is how to allocate space for different functional uses.

6 Jun 2025

Electron microscopy study shows how two enzymes work in tandem to process proteins

Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, because they unravel proteins tagged for destruction or recycling.

6 Jun 2025

Unveiling the biological frontier: CRAIC Technologies Circular Dichroism Microspectrometers pioneer molecular insights

CRAIC Technologies is proud to introduce Circular Dichroism Microspectroscopy. The field of biology is witnessing a transformative leap forward with the advent of Circular Dichroism (CD) Microspectroscopy, an innovative analytical technique that bridges micron-scale precision with biological applications.

From CRAIC Technologies, Inc. 5 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Fujifilm rebrands Life Sciences Companies to strengthen position as strategic partners for life, offering end-to-end solutions

FUJIFILM Corporation's Life Sciences Group companies, a portfolio of businesses offering products, services and comprehensive solutions that span all stages of therapeutic development from discovery through to commercialization, today announced new names and identities as part of a strategic positioning effort.

3 Jun 2025

Waters introduces BioResolve Protein A Affinity Columns to accelerate antibody titer measurement, enhancing process agility and batch quality

Waters Corporation today announced the launch of the BioResolve™ Protein A Affinity Columns with MaxPeak™ Premier Technology, providing precise titer measurements.

From Waters Corporation 2 Jun 2025

Advanced organoid model recreates complex liver architecture

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct in the liver periportal region.

29 May 2025

Necrosis may hold the key to unlocking longevity and space health solutions

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human aging, disease and even space travel, according to a new study from researchers at UCL, drug discovery company LinkGevity and the European Space Agency (ESA).

29 May 2025

Study combines biology and mathematics to reveal new insights into cell migration

Imagine cells navigating through a complex maze, guided by chemical signals and the physical landscape of their environment.

28 May 2025

High fat diet disrupts metabolism and increases disease risk

Consuming a high-fat diet can lead to a variety of health problems - not only weight gain but also an increased risk of diabetes and other chronic diseases.

28 May 2025

Cell Biology

New 3D model reveals hidden role of stem cells in sense of smell

Maternal iron deficiency disrupts embryonic sex determination in mice

ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

Scientists discover hundreds of new metabolites linked to the human microbiome

Inhibiting cancer cells' energy source with natural acid ester

CN Bio introduces cross-species DILI services to enhance in vitro to in vivo extrapolation during preclinical drug development

Patient-derived xenograft models may become an indispensable tool in precision oncology

New insights into the physical principles behind embryo development

Study offers new insights into how the body clears dead cells during stress

Shift Bioscience identifies novel single-gene target for safer cellular rejuvenation therapeutics

New study maps how cells allocate space to organelles during growth

Electron microscopy study shows how two enzymes work in tandem to process proteins

Unveiling the biological frontier: CRAIC Technologies Circular Dichroism Microspectrometers pioneer molecular insights

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Fujifilm rebrands Life Sciences Companies to strengthen position as strategic partners for life, offering end-to-end solutions

Waters introduces BioResolve Protein A Affinity Columns to accelerate antibody titer measurement, enhancing process agility and batch quality

Advanced organoid model recreates complex liver architecture

Necrosis may hold the key to unlocking longevity and space health solutions

Study combines biology and mathematics to reveal new insights into cell migration

High fat diet disrupts metabolism and increases disease risk

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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