Cell Biology

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Researchers elucidate the significance of birth in neural stem cell maintenance

A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Koya Kawase, a pediatric doctor at Nagoya City University Hospital, has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).

24 Jan 2025

Study reveals new mechanism behind gene expression regulation in animal cells

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem cells, and neural activation processes.

24 Jan 2025

Breakthrough study targets tumor cell clusters to prevent metastasis

Certain tumor types do not remain at their point of origin but spread throughout the body and form metastases.

24 Jan 2025

New machine learning approach improves single-cell data analysis

Our bodies are made up of around 75 billion cells. But what function does each individual cell perform and how greatly do a healthy person’s cells differ from those of someone with a disease?

23 Jan 2025

New technology tracks millions of cells simultaneously during organ development

Thanks to a new technology called Moscot ("Multi-Omics Single-Cell Optimal Transport"), researchers can now observe millions of cells simultaneously as they develop into a new organ-for example, a pancreas.

23 Jan 2025

FUJIFILM Irvine Scientific sells its medical media business to Astorg

FUJIFILM Irvine Scientific, Inc., a global leader in the innovation and manufacture of cell culture solutions for the life science and medical markets, today announced it entered into an agreement to sell its Medical Media Business Unit (MBU) to Astorg, a leading pan-European private equity firm with an extensive track record in global healthcare investments.

23 Jan 2025

Researchers discover how location affects immune cells' role in fighting disease

The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease.

22 Jan 2025

Study offers insight into how senescent cells survive after cancer treatment

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear.

22 Jan 2025

New insights into how cells clean and recycle waste

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste.

21 Jan 2025

Researchers uncover how PICH protein protects DNA during cell division

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer.

21 Jan 2025

Study finds anti-correlation of KLRG1 and PD-1 expression in tumor fighting T cells

A new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled "Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells."

21 Jan 2025

Research reveals sex differences in microglia response to injury

A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another "crew" of responders is busy clearing debris and repairing injured tissue.

21 Jan 2025

New imaging protocol enhances visualization of rare bone marrow cells

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to accurately identify rare LepR+ stromal cells.

21 Jan 2025

Ancient viral DNA plays crucial role in early embryo development

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life.

20 Jan 2025

Breakthrough reveals how DNA and RNA epigenetics work together to control genes

Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally.

17 Jan 2025

The diverse immunological functions of megakaryocytes

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

17 Jan 2025

New probes offer insight into cholesterol's role in Alzheimer's disease

The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry at Florida Atlantic University's Charles E. Schmidt College of Science, believes the key may lie in understanding how cholesterol and other lipids move through cells and affect their communication.

17 Jan 2025

RNA damage plays key role in sunburn reaction

Sunburn has traditionally been attributed to UV-induced DNA damage. However, a new study by the University of Copenhagen and Nanyang Technological University, Singapore, reveals that RNA, another vital cellular molecule, plays a major role in triggering acute sunburn reactions.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

Bidirectional movement drives DNA loop formation

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make loops into DNA could move in one direction only. The discovery, which is published in Cell, is key to understanding how these motors shape our genome and regulate our genes.

17 Jan 2025