Cell Biology

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Mapping cell structure by fusing protein images and interactions

If cells were "countries", the proteins would be their citizens organized into inter-connected towns and villages.

25 Nov 2021

Mtb's exotoxin secretion and trafficking mechanism revealed

Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years.

25 Nov 2021

MIT scientists discover how molecular clusters interact with chromosomes in the nucleus

A cell stores all of its genetic material in its nucleus, in the form of chromosomes, but that's not all that's tucked away in there. The nucleus is also home to small bodies called nucleoli -; clusters of proteins and RNA that help build ribosomes.

25 Nov 2021

Scientists use the synchrotron to better understand structure of cancer cells

A team of scientists led by the University of Surrey have used a special particle accelerator facility known as a synchrotron to better understand the structure of cancer cells.

25 Nov 2021

Treatment with antihistamines associated with improved responses to immunotherapy

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

24 Nov 2021

Context-dependent, untangled persistency facilitates value signal coding across the brain

In 2019 University of California San Diego researchers discovered the area of the brain where "value decisions" are made.

24 Nov 2021

New technique may be a significant leap forward in the understanding of human cells

Most human diseases can be traced to malfunctioning parts of a cell — a tumor is able to grow because a gene wasn't accurately translated into a particular protein or a metabolic disease arises because mitochondria aren't firing properly, for example. But to understand what parts of a cell can go wrong in a disease, scientists first need to have a complete list of parts.

24 Nov 2021

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

When something disrupts hormone binding to the receptor, such as environmental compounds or pollutants, called endocrine disrupting chemicals (EDCs), the results can be harmful and, in some cases, lead to certain forms of cancer.

24 Nov 2021

The antimicrobial properties of the lungfish cocoon

Researchers investigate if the immune system of lungfish plays a role in estivation.

24 Nov 2021

Irregular body clock plays key role in driving inflammation in the immune cells, research shows

New research from RCSI has demonstrated the significant role that an irregular body clock plays in driving inflammation in the body's immune cells, with implications for the most serious and prevalent diseases in humans.

24 Nov 2021

Study offers insights into how Shigella delivers bacterial proteins into our cells

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells.

24 Nov 2021

Vaping linked to dysregulation of mitochondrial genes and immune response genes

Since they hit the market, e-cigarettes have been touted as a safe alternative to tobacco cigarettes for adult smokers.

24 Nov 2021

New "image analysis pipeline" provides insight into how disease changes the body

A new "image analysis pipeline" is giving scientists rapid new insight into how disease or injury have changed the body, down to the individual cell.

24 Nov 2021

New virtual reality platform could revolutionize the way single-cell omics data is analyzed

Science has the technology to measure the activity of every gene within a single individual cell, and just one experiment can generate thousands of cells worth of data.

23 Nov 2021

Study identifies key factor sustaining malignant tumor state

In a study published in Nature Cancer, researchers led by Prof. Cedric Blanpain, WELBIO investigator, Director of the Laboratory of Stem Cells and Cancer and Professor at the Université libre de Bruxelles, Belgium, demonstrated that NR2F2 is an essential regulator of malignant tumor state by controlling cancer stem cell and tumor maintenance in mouse and human cancers.

22 Nov 2021

Clearing old, dysfunctional cells in fat alleviates diabetes

Eliminating old, dysfunctional cells in human fat also alleviates signs of diabetes, researchers from UConn Health report. The discovery could lead to new treatments for Type 2 diabetes and other metabolic diseases.

22 Nov 2021

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists from Nagoya University, Japan, led by Associate Professor Akio Masuda, have recently identified the mechanism behind regulated splicing of large constitutive exons which are rich in disordered regions, and their potential involvement in the assembly of transcription factors.

21 Nov 2021

Study explores connections between COVID-19 severity and gene expression in immune cells

New research shows how genetic variations linked to severe cases of COVID-19 affect our immune cells.

21 Nov 2021

Researchers discover new type of cell that may help regulate heart rate

Researchers at the University of Notre Dame discovered a new type of cell in the heart that may help regulate heart rate, and could be an important key in understanding certain types of congenital heart defects and other diseases that involve the heart.

21 Nov 2021

New study uncovers a mechanism of sleep in zebrafish

Why do humans spend a third of their lives sleeping? Why do animals sleep? Throughout evolution sleep has remained universal and essential to all organisms with a nervous system, including invertebrates such as flies, worms, and even jellyfish.

21 Nov 2021

Cell Biology

Mapping cell structure by fusing protein images and interactions

Mtb's exotoxin secretion and trafficking mechanism revealed

MIT scientists discover how molecular clusters interact with chromosomes in the nucleus

Scientists use the synchrotron to better understand structure of cancer cells

Treatment with antihistamines associated with improved responses to immunotherapy

Context-dependent, untangled persistency facilitates value signal coding across the brain

New technique may be a significant leap forward in the understanding of human cells

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

The antimicrobial properties of the lungfish cocoon

Irregular body clock plays key role in driving inflammation in the immune cells, research shows

Study offers insights into how Shigella delivers bacterial proteins into our cells

Vaping linked to dysregulation of mitochondrial genes and immune response genes

New "image analysis pipeline" provides insight into how disease changes the body

New virtual reality platform could revolutionize the way single-cell omics data is analyzed

Study identifies key factor sustaining malignant tumor state

Clearing old, dysfunctional cells in fat alleviates diabetes

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

Study explores connections between COVID-19 severity and gene expression in immune cells

Researchers discover new type of cell that may help regulate heart rate

New study uncovers a mechanism of sleep in zebrafish

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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