Cell Biology

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Johns Hopkins Medicine researchers challenge the prevailing belief on how nasal cells process scent

Johns Hopkins Medicine researchers say they have evidence to potentially overturn a prevailing belief in a type of important signaling within cells.

18 Aug 2022

Researchers visualize antigen-bound T-cell receptor at atomic resolution

T cells are our immune system’s customized tools for fighting infectious diseases and tumor cells. On their surface, these special white blood cells carry a receptor that recognizes antigens.

18 Aug 2022

Key gene sheds light on how people develop tolerance to pain-relievers over time

UF Scripps Biomedical Research scientists have a discovered a key gene that is shedding light on how people develop tolerance to pain-relievers over time, a problem that raises risk of addiction and overdose.

18 Aug 2022

Immune cells preferentially use cellular waste products to power their function

The immune cells that protect us from infection and cancer seek out a wide array of fuel sources to power their function - including some long thought to be cellular waste products.

17 Aug 2022

Researchers create novel mouse model for mapping protein communication between organs

Our many different organ systems are in constant communication with each other. During exercise, for example, muscles send out signals to fat and liver tissue to release their energy sources.

17 Aug 2022

Research suggests a new model of how beige fat biogenesis is controlled

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

17 Aug 2022

Innovative technology revels the impact of environmental conditions on RNA structures in living cells

The impact of environmental conditions on the dynamic structures of RNAs in living cells has been revealed by innovative technology developed by researchers at the John Innes Centre.

17 Aug 2022

New technique keeps the cells alive during RNA extraction

RNA sequencing allows scientists to study the expression of genes in a cell. Since messenger RNA (mRNA) is generated from a DNA gene, that information can be used to identify the original gene sequence and thus measure the activity of thousands of genes (i.e. the transcriptome) in these cells.

17 Aug 2022

Scientists unravel the development of main immune cell population residing in the brain

New research published today by the University of Southampton shows new insight in how our brain develops, that can pave the way for treating neurological disorders.

16 Aug 2022

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Peter Adams, Ph.D., and Bing Ren, Ph.D., have been awarded a new grant from the National Institutes of Health (NIH) to join a multi-institution initiative studying the process of aging.

16 Aug 2022

Scientists turn toward artificial intelligence for unraveling cell biology

For our cells to proliferate, differentiate or migrate, the nucleus needs the help of its cytoskeleton, the scaffold surrounding the nucleus which provides cells with shape and solid structure.

16 Aug 2022

UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation.

16 Aug 2022

KAUST bioscientists develop new method to study the bone marrow microenvironment in greater detail

Deep molecular analysis of the bone marrow microenvironment reveals that the cells regulating blood stem cell maintenance are more diverse than expected and have features likely to be conserved between species.

16 Aug 2022

Intestinal tissue-resident lymphocytes regulate their activity depending on glucose availability

A new study led by Marc Veldhoen, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Associate Professor at Faculdade de Medicina de Lisboa (FMUL) and published today in the scientific journal PNAS (Proceedings of the National Academy of Sciences of the United States of America) discovered that white blood cells that reside in the intestines, a specific group of immune cells called tissue-resident lymphocytes, use sugar as an energy source and have a faster metabolism than lymphocytes that circulate in the blood.

15 Aug 2022

Study paves new way to develop a predictive biomarker for TRAIL therapy

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Therefore, various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, but a certain population of cancer patients does not respond to the therapy.

15 Aug 2022

Researchers engineer artificial replicas of G protein-coupled receptors

How do signals from outside the cell cause a response inside it? Such outside signals could be hormones or neurotransmitters. To notice them, the cell's surface possesses receptors. One of the key classes of such receptors are so-called G protein-coupled receptors, or in short GPCRs.

15 Aug 2022

Cell Biology

Johns Hopkins Medicine researchers challenge the prevailing belief on how nasal cells process scent

Researchers visualize antigen-bound T-cell receptor at atomic resolution

Key gene sheds light on how people develop tolerance to pain-relievers over time

Immune cells preferentially use cellular waste products to power their function

Researchers create novel mouse model for mapping protein communication between organs

Research suggests a new model of how beige fat biogenesis is controlled

Innovative technology revels the impact of environmental conditions on RNA structures in living cells

New technique keeps the cells alive during RNA extraction

Scientists unravel the development of main immune cell population residing in the brain

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Scientists turn toward artificial intelligence for unraveling cell biology

UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

KAUST bioscientists develop new method to study the bone marrow microenvironment in greater detail

Intestinal tissue-resident lymphocytes regulate their activity depending on glucose availability

Study paves new way to develop a predictive biomarker for TRAIL therapy

Researchers engineer artificial replicas of G protein-coupled receptors

Why is COVID-19 more severe in people older than 50?

Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

New method for 3D culture accurately quantifies how cancer cells generate forces to spread within tissue

New evidence explains why thinking hard makes one feel worn out

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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