Cell Biology

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Oxytocin induces epicardial cell proliferation, study finds

The neurohormone oxytocin is well-known for promoting social bonds and generating pleasurable feelings, for example from art, exercise, or sex. But the hormone has many other functions, such as the regulation of lactation and uterine contractions in females, and the regulation of ejaculation, sperm transport, and testosterone production in males.

30 Sep 2022

Study reveals the role of autophagy in competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process “autophagy.”

30 Sep 2022

Love hormone can activate heart repair mechanisms after cardiac injury, study finds

Researchers show for the first time that the neurohormone oxytocin has a previously unsuspected function in both zebrafish and human cell cultures: it stimulates mature cells in the epicardium of the heart to become stem-like cells, which can replace heart cells lost after damage.

30 Sep 2022

Tufted cells are better at recognizing smells than mitral cells, researchers say

Since their discovery over 100 years ago, neurons in the brain's olfactory bulb called tufted cells have been difficult to study.

29 Sep 2022

Researchers propose guidelines and methods for consistently generating high-quality brain organoids

By using stem cells to grow miniature brain-like organs in the lab, scientists have opened a new avenue for studies of neurological development, disease and therapies that can't be conducted in living people.

29 Sep 2022

“Mystery gene” matures a main component of the cell skeleton

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to remain elusive for as long as forty years.

29 Sep 2022

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Despite recent advancements in our knowledge of the pathogenic mechanisms of ulcerative colitis, there is still a considerable unmet medical need for the treatment of ulcerative colitis.

29 Sep 2022

Cancer cells 'hijack' a process used by healthy cells to spread around the body, research finds

Cancer Research UK-funded scientists have discovered that cancer cells 'hijack' a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.

29 Sep 2022

UAB study finds distinct kidney resident macrophage subpopulations located in spatially discrete microenvironments

Macrophages are immune cells that engulf and digest pathogens, cancer cells or cellular debris. The kidneys - like other tissues in the body - contain kidney resident macrophages, or KRMs, from the time of birth.

28 Sep 2022

UMass Amherst scientists delve into the mysteries of how cells manage stress

In new research recently published in the journal Cell Reports, a team of scientists from the University of Massachusetts Amherst delved into the mysteries of how cells weather stress.

28 Sep 2022

Study reveals how pathogens exploit a key cellular process to intoxicate cells

What our work shows is how a complex in the center of the cell, the ER-Golgi interaction region, controls plasma membrane cholesterol, which is essential for many cellular functions, if not essential for multicellular life.

28 Sep 2022

Scientists visualize antibiotics in action inside a pathogenic bacterium

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival.

28 Sep 2022

Insights into the biology of virtual memory CD8+ T cells

Virtual memory CD8+ T cells (TVM) are a relatively recent discovery in humans. A new review discusses what is known about them from mouse models and their cellular equivalents in humans, as described in the peer-reviewed Journal of Interferon & Cytokine Research.

28 Sep 2022

UArizona researchers discover new protein that is responsible for controlling cell growth in yeasts

Like bacteria, yeasts are found everywhere, even in and around our bodies. And, as with bacteria, you can become infected by yeasts and become ill. Yeasts infect about 150 million people a year and kill about 1.7 million, especially those who are immunocompromised.

28 Sep 2022

Shape-shifting mitochondria influence Th17 cells’ propensity for autoimmune activity

A new study focused on the immune system's Th17 cells suggests that the shape and function of their mitochondria (the powerhouse of cells) is important in autoimmune and inflammatory disorders, such as multiple sclerosis.

28 Sep 2022

Live imaging and cellular barcoding reveal how new stem cells are vetted for quality

Using live imaging and cellular barcoding, researchers in the Stem Cell Program at Boston Children's Hospital have glimpsed how new stem cells - in this case, blood stem cells - are vetted for quality soon after they're born.

28 Sep 2022

How the gut microbiome could affect COVID-19 severity

Researchers review the potential role of the gut microbiome in determining severe COVID-19.

27 Sep 2022

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Researchers from Barts Cancer Institute (BCI) at Queen Mary University of London, the Italian Institute for Genomic Medicine, and the University of Milan have identified a novel role for a cancer-causing gene in controlling an important genetic process that underpins genetic variation in prostate cancer.

27 Sep 2022

UVA researchers solve a decades-old mystery about how bacteria can move

University of Virginia School of Medicine researchers and their collaborators have solved a decades-old mystery about how E. coli and other bacteria are able to move.

27 Sep 2022

Novel CRISPR-based method benefits further cancer studies

Researchers have identified a mechanism by which an oncogene commonly activated in cancer patients affects the growth rate of cells.

27 Sep 2022

Cell Biology

Oxytocin induces epicardial cell proliferation, study finds

Study reveals the role of autophagy in competitive elimination of cancer cells

Love hormone can activate heart repair mechanisms after cardiac injury, study finds

Tufted cells are better at recognizing smells than mitral cells, researchers say

Researchers propose guidelines and methods for consistently generating high-quality brain organoids

“Mystery gene” matures a main component of the cell skeleton

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Cancer cells 'hijack' a process used by healthy cells to spread around the body, research finds

UAB study finds distinct kidney resident macrophage subpopulations located in spatially discrete microenvironments

UMass Amherst scientists delve into the mysteries of how cells manage stress

Study reveals how pathogens exploit a key cellular process to intoxicate cells

Scientists visualize antibiotics in action inside a pathogenic bacterium

Insights into the biology of virtual memory CD8+ T cells

UArizona researchers discover new protein that is responsible for controlling cell growth in yeasts

Shape-shifting mitochondria influence Th17 cells’ propensity for autoimmune activity

Live imaging and cellular barcoding reveal how new stem cells are vetted for quality

How the gut microbiome could affect COVID-19 severity

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

UVA researchers solve a decades-old mystery about how bacteria can move

Novel CRISPR-based method benefits further cancer studies

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