Cell Biology

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Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule.

10 Oct 2022

KAUST research could open new avenues for cancer drug development

Precise details of how a master regulator of gene expression binds its activating partner could open new avenues for cancer drug development.

10 Oct 2022

Age plays a more important role than genetics in affecting gene expression profiles as we get older

Amid much speculation and research about how our genetics affect the way we age, a University of California, Berkeley, study now shows that individual differences in our DNA matter less as we get older and become prone to diseases of aging, such as diabetes and cancer.

7 Oct 2022

NEI researchers create a high-resolution map of retinal cell chromatin contract points

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus.

7 Oct 2022

Scientists develop an unprecedented animal model to investigate Ewing sarcoma

Ewing sarcoma is the second most frequent bone tumour in children, adolescents, and young adults. There is no specific treatment for this disease and current management is still limited to surgery, radiotherapy, and chemotherapy.

7 Oct 2022

Opioid receptor levels in brown fat found to be dependent on the length of daylight hours

Researchers from the Turku PET Centre, Finland, have observed that the length of daylight hours impacts opioid receptor levels in brown fat.

7 Oct 2022

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

A well-functioning immune system is essential for protection against infections. However, with increasing age, the functioning of the immune system diminishes, which is also due to age-related damage in hematopoietic (blood) stem cells.

7 Oct 2022

Researchers take new approach to studying the development of the human brain

Researchers at ETH Zurich are growing human brain-like tissue from stem cells and are then mapping the cell types that occur in different brain regions and the genes that regulate their development.

7 Oct 2022

Research shows highly disturbed metabolic pathways in people with type 2 diabetes

Using state of the art techniques, researchers from Uppsala University have shown that the metabolism in patients with type 2 diabetes and prediabetes was much more disturbed than previously known, and that it varied between organs and severity of the disease.

7 Oct 2022

Discovery could play an important role in future medicines to heal damaged hearts

Scientists at the UNC School of Medicine have made a significant advance in the promising field of cellular reprogramming and organ regeneration, and the discovery could play a major role in future medicines to heal damaged hearts.

6 Oct 2022

Scientists discover a new drug-resistance mechanism in breast cancer

Scientists from Università Cattolica in Rome, together with colleagues from the IIGM Foundation (part of Candiolo Institute at Turin), have discovered a new drug-resistance mechanism in breast cancer that leads to the formation of cancer stem cells, (the cells that feed the tumor and cause relapse and metastasis).

6 Oct 2022

Improved brain organoids provide cellular and molecular insights into autism

Whatever you do, don't call them "mini-brains," say University of Utah Health scientists. Regardless, the seed-sized organoids - which are grown in the lab from human cells - provide insights into the brain and uncover differences that may contribute to autism in some people.

6 Oct 2022

The involvement of minor intron-containing gene-encoded proteins in viral infections

Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

6 Oct 2022

Labskin to develop new revolutionary approach to testing for radiation exposure

Labskin is delighted to announce our selection by The Intelligence Advanced Research Projects Activity (IARPA), part of the US Office of the Director of National Intelligence, to join a team of experts to develop new ways to evaluate radiation exposure in civilians and military personnel.

6 Oct 2022

Cell Biology

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

KAUST research could open new avenues for cancer drug development

Age plays a more important role than genetics in affecting gene expression profiles as we get older

NEI researchers create a high-resolution map of retinal cell chromatin contract points

Scientists develop an unprecedented animal model to investigate Ewing sarcoma

Opioid receptor levels in brown fat found to be dependent on the length of daylight hours

Study uncovers how the TAZ protein protects hematopoietic stem cells from aging

Researchers take new approach to studying the development of the human brain

Research shows highly disturbed metabolic pathways in people with type 2 diabetes

Discovery could play an important role in future medicines to heal damaged hearts

Scientists discover a new drug-resistance mechanism in breast cancer

Improved brain organoids provide cellular and molecular insights into autism

The involvement of minor intron-containing gene-encoded proteins in viral infections

Labskin to develop new revolutionary approach to testing for radiation exposure

Stanford researchers create new technique for controlling protein production

PSI researchers optimize a method for tumor diagnosis using radionuclides

Antibody escape mutations of SARS-CoV-2 BA.2.75

Immune cell defect tied to the risk of developing rare bacterial infection

Novel technique helps to detangle how phosphorylation regulates cellular events

Research sheds light on how the cell selects suitable protein fragments for robust T-cell response

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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