Cell Biology

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Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth.

1 Sep 2022

Researchers demonstrate improved culture of primate induced pluripotent stem cells

The following study transplanted iPSCs derived from two NHP species, chimpanzee and pigtailed macaque, into blastocysts from another NHP species – the rhesus macaque.

1 Sep 2022

Cell Counting Without Slides to Reduce Waste and Cost

Until recently, cells were typically counted on a reusable quartz hemocytometer.

From DeNovix Inc. 1 Sep 2022

Scientists uncover how a build-up of harmful protein starts to happen in Parkinson's disease

Scientists at the Francis Crick Institute, UCL and the University of Edinburgh have uncovered how a build-up of harmful protein starts to happen within neurons in Parkinson's disease, ultimately causing nerve cell death.

30 Aug 2022

Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

All normal human tissues acquire mutations over time. Some of these mutations may be driver mutations that promote the development of cancer through increased proliferation and survival, while other mutations may be neutral passenger mutations that have no impact on cancer development.

30 Aug 2022

Research provides a major step forward to growing human kidney in a dish

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world.

30 Aug 2022

Study reveals a vital route through which fascin promotes cancer development

The study reveals an important route through which fascin promotes cancer development and provides insights into potential pathways that could block its action.

30 Aug 2022

Study reinforces the potential of Huntington’s treatments that target glia cells

Huntington's disease – a hereditary and fatal genetic disorder – has long been considered a neuronal disease due to the permanent loss of medium spiny motor neurons, the death of which over time is responsible for the clinical hallmarks of the disease: involuntary movements, problems with coordination, cognitive decline, depression, and psychosis.

30 Aug 2022

New labeling technique helps analyze the contents of exosomes from cells

Our cells are constantly communicating, and scientists have developed an efficient way to find out what messages they are sending in protein-packed biological suitcases called exosomes.

30 Aug 2022

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial mutations to observe these tiny organelles.

30 Aug 2022

Intracellular bacteria protect their host against giant viruses, research shows

Amoebae receive surprising support in defense against viruses: The bacteria they are infected with prevent them from being destroyed by giant viruses.

29 Aug 2022

Viruses modify host cellular machinery to produce high amounts of viral progeny

The study, published in Nature Communications, shows a new mechanism whereby viruses modify cellular machinery so that it can better read the instructions in the genome of the invading virus.

29 Aug 2022

Study shows how the brain's tool for waste clearance malfunctions during bacterial meningitis

Bacterial meningitis is a life-threatening infectious disease of the brain that leaves many survivors with long-lasting neurological impairments.

29 Aug 2022

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't wedge themselves in between the molecules.

29 Aug 2022

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

Neurodegenerative disorders such as Alzheimer's and Parkinson's disease are associated with atypical proteins that form tangles in the brain, killing neurons.

29 Aug 2022

UB study reveals a mechanism of gene evolution generating mucin function

From the slime coating slugs to the saliva in our mouths, many slippery bodily fluids contain mucus. So how did this marvel of biology evolve?

26 Aug 2022

Researchers develop a protein thermal shift chip for COVID-19

Announcing a new publication for Acta Materia Medica journal. Traditional protein chips are based on solid chips and cannot enable drug and target screening in a label-free manner.

26 Aug 2022

Beckman Coulter Life Sciences partners with Flownamics on bioprocess culture monitoring solution

Beckman Coulter Life Sciences, a global leader in laboratory automation and biotechnology innovation, announces a partnership with Flownamics to create an automated, on-line solution for bioprocess culture monitoring and control. This delivers a critical and practical update to the significant unmet need for automated, real-time cell analysis in the current bioprocessing environment.

From Beckman Coulter Life Sciences 26 Aug 2022

UC Davis research reveals a novel role for how tau functions in healthy nerve cells

In Alzheimer's Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons wither and die.

25 Aug 2022

Mouse embryoids offer a promising model system to spur research into embryonic development and disease

Scientists funded in part by the National Institutes of Health have generated a mouse embryo model, or embryoid, that develops beyond neurulation—formation of the neural tube, which gives rise to the central nervous system—and closely mirrors natural mouse embryos 8.5 days after fertilization.

25 Aug 2022

Cell Biology

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers demonstrate improved culture of primate induced pluripotent stem cells

Cell Counting Without Slides to Reduce Waste and Cost

Scientists uncover how a build-up of harmful protein starts to happen in Parkinson's disease

Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

Research provides a major step forward to growing human kidney in a dish

Study reveals a vital route through which fascin promotes cancer development

Study reinforces the potential of Huntington’s treatments that target glia cells

New labeling technique helps analyze the contents of exosomes from cells

Researchers create first mouse model carrying a disease-associated mitochondrial mutation

Intracellular bacteria protect their host against giant viruses, research shows

Viruses modify host cellular machinery to produce high amounts of viral progeny

Study shows how the brain's tool for waste clearance malfunctions during bacterial meningitis

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

UB study reveals a mechanism of gene evolution generating mucin function

Researchers develop a protein thermal shift chip for COVID-19

Beckman Coulter Life Sciences partners with Flownamics on bioprocess culture monitoring solution

UC Davis research reveals a novel role for how tau functions in healthy nerve cells

Mouse embryoids offer a promising model system to spur research into embryonic development and disease

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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