Cell Biology

RSS

Newly designed nanoparticles target the body’s immune cells to turn them against cancer

Scientists of the department of Advanced Organ Bioengineering and Therapeutics (Faculty of S&T, TechMed Centre) recently published a novel cancer immune therapy in the scientific journal Nature Communications.

11 Aug 2022

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Study finds genetic alterations in healthy cells that match with the tumor cells

A new study offers the possibility of unmasking genetic mutations in an organ well before commonly-used screening techniques detect signs of cancer.

10 Aug 2022

Next-generation sequencing system yields results comparable to traditional diagnostics

In the pursuit of accurate diagnoses for illnesses, doctors have traditionally used multiple methods — including culturing patient samples on a wide variety of media, reviewing countless medical records and analyzing clinical data using complex mathematical algorithms — to try to identify the bacterium, virus, fungus or other pathogen responsible for an infection.

10 Aug 2022

Neuronal cilia are important for dopamine receptor 1 signaling, study shows

A historically overlooked rod-like projection present on nearly every cell type in the human body may finally be getting its scientific due: A new study has found that these appendages, called cilia, on neurons in the brain have a key role in ensuring a specific dopamine receptor's signals are properly received.

9 Aug 2022

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Around 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in them being significantly smaller than the eyes of wild zebrafish.

9 Aug 2022

Researchers create the most bio-realistic and complex computer models of brain cells

Cedars-Sinai investigators have created the most bio-realistic and complex computer models of individual brain cells - in unparalleled quantity.

9 Aug 2022

Novel AI tools accurately predict the role of DNA’s regulatory elements

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

9 Aug 2022

Sustainable Science; What does the future look like?

We speak to Ali Safavi, CEO and Founder of Grenova about sustainable science, the impact life sciences research is having on our planet, and the solutions they offer for laboratories to help reduce their plastic waste.

From Grenova 8 Aug 2022

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

In the beginning, there was boredom. Following the emergence of cellular life on earth, some 3.5 billion years ago, simple cells lacking a nucleus and other detailed internal structure dominated the planet. Matters would remain largely unchanged in terms of evolutionary development in these so-called prokaryotic cells - the bacteria and archaea - for another billion and a half years.

8 Aug 2022

Researchers develop new method for visualizing single cell protein secretion with stunning resolution

We have recently witnessed the stunning images of distant galaxies revealed by the James Webb telescope, which were previously visible only as blurry spots.

5 Aug 2022

Locusts can differentiate between cancer cells and healthy cells, research shows

Researchers at Michigan State University have shown that locusts can not only "smell" the difference between cancer cells and healthy cells, but they can also distinguish between different cancer cell lines.

5 Aug 2022

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

A research team led by André Marques at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, has uncovered the profound effects of an atypical mode of chromosome arrangement on genome organization and evolution.

4 Aug 2022

KAIST researchers engineer a bacterial strain capable of producing lutein

A research group at KAIST has engineered a bacterial strain capable of producing lutein. The research team applied systems metabolic engineering strategies, including substrate channeling and electron channeling, to enhance the production of lutein in an engineered Escherichia coli strain.

4 Aug 2022

scRNA-seq of SARS-CoV-2 infected lung organoids finds NFKB Inhibitor Alpha increased in infected cells

Researchers develop a genetically modified airway organoid system, which overcomes challenges related to natural variations in ACE2 levels

4 Aug 2022

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Mitochondria are organelles found within most cells, best known for generating the chemical energy required to power cellular functions.

4 Aug 2022

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety of chronic human ailments, including obesity, type 2 diabetes, atherosclerosis, cancer, non-alcoholic fatty liver disease and inflammatory bowel disease.

4 Aug 2022

Scientists develop a novel, highly-efficient sample preparation method for single-cell proteomics

The proteins that make up our cells hold within an entire world of information, which, when unlocked, can give us insights into the origins of many essential biological phenomena.

4 Aug 2022

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

Cell Biology

Newly designed nanoparticles target the body’s immune cells to turn them against cancer

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Study finds genetic alterations in healthy cells that match with the tumor cells

Next-generation sequencing system yields results comparable to traditional diagnostics

Neuronal cilia are important for dopamine receptor 1 signaling, study shows

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Researchers create the most bio-realistic and complex computer models of brain cells

Novel AI tools accurately predict the role of DNA’s regulatory elements

Sustainable Science; What does the future look like?

Researchers challenge a popular scenario put forward to explain the arrival of the first eukaryotic organisms

Researchers develop new method for visualizing single cell protein secretion with stunning resolution

Locusts can differentiate between cancer cells and healthy cells, research shows

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

KAIST researchers engineer a bacterial strain capable of producing lutein

scRNA-seq of SARS-CoV-2 infected lung organoids finds NFKB Inhibitor Alpha increased in infected cells

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Scientists develop a novel, highly-efficient sample preparation method for single-cell proteomics

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

Latest Life Science News