Cell Biology

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Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

RIT scientist receives $1.7 million NIH award to study how cells control the size of organelles

A Rochester Institute of Technology scientist hopes that a better understanding of how living cells maintain the size of their organelles can lead to therapies for neurodegenerative diseases.

16 Sep 2022

Deep AI models fail to capture the configural nature of human shape perception

Deep convolutional neural networks (DCNNs) don't see objects the way humans do – using configural shape perception – and that could be dangerous in real-world AI applications, says Professor James Elder, co-author of a York University study published today.

16 Sep 2022

U of M researchers receive grant to map senescent cells in preclinical studies and human tissues

Researchers at the University of Minnesota Medical School and the Institute on the Biology of Aging and Metabolism were awarded a total of $19.3 million in grants from the National Institutes of Health Common Fund to map senescent cells in preclinical studies and human tissues as part of the SenNet Consortium.

16 Sep 2022

Researchers use sea anemone to understand how behavior impacts body shape during early development

As humans, we know that an active lifestyle gives us some control over our form. When we hit the pavement, track our steps, and head to the gym, we can maintain muscle development and reduce body fat.

16 Sep 2022

Study evaluates how rapid tests will perform when challenged with future SARS-CoV-2 variants

The availability of rapid antigen tests has significantly advanced efforts to contain the spread of COVID-19, but every new variant of concern raises questions about whether diagnostic tests will still be effective.

15 Sep 2022

Study investigates link between plasma miRNAs and cognitive function among cognitively normal men

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 17, entitled, "Extracellular microRNA and cognitive function in a prospective cohort of older men: The Veterans Affairs Normative Aging Study."

15 Sep 2022

New mechanism may prevent the natural aging of immune cells

A new mechanism that slows down and may even prevent the natural aging of immune cells – one of the nine 'hallmarks of aging' – has been identified by an international team led by UCL scientists.

15 Sep 2022

Scientists unravel the molecular origin of rare genetic disease cystinosis

The rare genetic disease cystinosis is caused by mutations in the gene for a protein called cystinosin. A team of scientists has now solved the structure of cystinosin and determined how mutations interfere with its normal function, providing insights into the underlying mechanisms and suggesting a way to develop new treatments for the disease.

15 Sep 2022

Disruption of actin cytoskeleton is key to triggering human immune response, research finds

Researchers from Cleveland Clinic's Florida Research and Innovation Center (FRIC) found that disruption of a cellular structure, known as the actin cytoskeleton, is a "priming signal" for the body to respond to a virus.

15 Sep 2022

New method evaluates how mutations to SARS-CoV-2 can affect antibody recognition in rapid antigen tests

A research team funded by the National Institutes of Health has shown that commercially available rapid antigen tests can detect past and present variants of concern and has identified potential mutations that may impact test performance in the future.

15 Sep 2022

Mechanical forces generated by T cells influence the destruction of cancer cells

As a part of our immune defenses, cytotoxic T cells – or killer T cells – seek out and destroy cells that are infected or cancerous. This process is essential for the body's defense against diseases.

15 Sep 2022

Large molecules glom together into dense droplets to create squishy circuits in cells

An emerging field explores how groups of molecules condense together inside cells, the way oil droplets assemble and separate from water in a vinaigrette.

14 Sep 2022

Study reveals cellular underpinnings of motor memory acquisition and consolidation

When you are first learning how to ride a bicycle or play a musical instrument, your physical movements are uncoordinated at best.

14 Sep 2022

Scientists harness the potential of bacteria to help create synthetic cells with lifelike functionality

Scientists have harnessed the potential of bacteria to help build advanced synthetic cells which mimic real life functionality.

14 Sep 2022

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration.

14 Sep 2022

MIT researchers use new technique to gather insight into repetitive protein sequences

About 70 percent of all human proteins include at least one sequence consisting of a single amino acid repeated many times, with a few other amino acids sprinkled in. These "low-complexity regions" are also found in most other organisms.

13 Sep 2022

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

Through extensive single-cell analysis, researchers at The University of Texas MD Anderson Cancer Center have created a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, highlighting previously unappreciated roles these immune cells play in tumor development and treatment outcomes.

13 Sep 2022

New drug marks cancer cells for destruction by the immune system

Tumor cells are notoriously good at evading the human immune system; they put up physical walls, wear disguises and handcuff the immune system with molecular tricks.

13 Sep 2022

Gut commensal bacteria promote the development of virus-induced cancer by suppressing the immune system

Gut bacteria have a profound impact on health by aiding digestion, providing nutrients and metabolites, and working with the immune system to fend off pathogens.

13 Sep 2022

Cell Biology

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

RIT scientist receives $1.7 million NIH award to study how cells control the size of organelles

Deep AI models fail to capture the configural nature of human shape perception

U of M researchers receive grant to map senescent cells in preclinical studies and human tissues

Researchers use sea anemone to understand how behavior impacts body shape during early development

Study evaluates how rapid tests will perform when challenged with future SARS-CoV-2 variants

Study investigates link between plasma miRNAs and cognitive function among cognitively normal men

New mechanism may prevent the natural aging of immune cells

Scientists unravel the molecular origin of rare genetic disease cystinosis

Disruption of actin cytoskeleton is key to triggering human immune response, research finds

New method evaluates how mutations to SARS-CoV-2 can affect antibody recognition in rapid antigen tests

Mechanical forces generated by T cells influence the destruction of cancer cells

Large molecules glom together into dense droplets to create squishy circuits in cells

Study reveals cellular underpinnings of motor memory acquisition and consolidation

Scientists harness the potential of bacteria to help create synthetic cells with lifelike functionality

NIH researchers identify specific network of proteins critical to restore hearing in zebrafish

MIT researchers use new technique to gather insight into repetitive protein sequences

Study highlights role of tumor-infiltrating B cells, plasma cells in cancer development and treatment outcomes

New drug marks cancer cells for destruction by the immune system

Gut commensal bacteria promote the development of virus-induced cancer by suppressing the immune system

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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